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Thank you Douglas for this clarification.

So, correction of inhomogeneities and intensity normalization would have no 
positive effect on the PET/MR coregistration ?

Best,
Matt

> Le 3 janv. 2019 à 20:04, Greve, Douglas N.,Ph.D. <dgr...@mgh.harvard.edu> a 
> écrit :
> 
> I doubt it would make much difference. If your PET has lots of 
> extracerebral uptake, then I might use something that has not been skull 
> stripped (eg, orig.mgz, T1.mgz, nu.mgz). If it does not  have much 
> extracerebral, then using brain.mgz is probably better.
> 
> On 12/31/18 10:53 AM, Bruce Fischl wrote:
>> HI Matt
>> 
>> yes, I would agree, but Doug will give you the definitive answer
>> 
>> cheers
>> Bruce
>> On Fri, 28 Dec 2018, Matthieu Vanhoutte wrote:
>> 
>>>        External Email - Use Caution
>>> 
>>> Dear Freesurfer’s experts,
>>> 
>>> I used mri_coreg command to coregister PET image onto T1 volume. 
>>> Basically, this command coregister PET image onto orig.mgz volume 
>>> (default target). However, I wonder if T1.mgz wouldn’t be a better 
>>> target since it has been corrected for inhomogeneities and intensity 
>>> normalized ?
>>> 
>>> Thanks for helping !
>>> 
>>> Best,
>>> Matt
>>> 
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>> 
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