Re: [Freesurfer] Pial Surfaces Cutting off Gyri

2010-04-07 Thread Sherri Novis
Thank you Bruce. I've had this prob randomly before - but recently it's been 
each of the last 10 datasets - so I think its a process issue that I introduced 
- but would love help from any direction.

If I use the upload site - which files to you need?  will send wm.mgz, ?h.orig 
surface - any others?

Thank you -
Sherri



-Original Message-
>From: Bruce Fischl 
>Sent: Apr 7, 2010 1:15 PM
>To: Sherri Novis 
>Cc: Sita Kakunoori , freesurfer@nmr.mgh.harvard.edu
>Subject: Re: [Freesurfer] Pial Surfaces Cutting off Gyri
>
>Hi Sherri,
>
>you may also have a topological defect near those control points, which 
>is causing the surfaces to lose the wm (and hence the gm also). What does 
>the wm.mgz look like there? Is the wm segmented correctly but not 
>included in the ?h.orig surface? If you upload this data we can take a 
>look, if you want.
>Bruce
>
>
>On Wed, 7 Apr 2010, Sherri Novis wrote:
>
>> Thanks Sita. I have struggled with how to capture very ghostly gray matter.  
>> Sometimes throwing a CP in it works (I understand now this may be hosing it 
>> sometimes) - if AR2-cp w/CPs in white matter is not driving the pial 
>> surfaces to capture all the gray - is the only way to capture the ghostly 
>> gray matter to directly edit the pial surface?
>>
>> I was trying to avoid that. I was told don't ever edit the pial surfaces - 
>> not sure why though.  Will manual edits of the pial surfaces cause other 
>> problems in getting surface segmentation stats?
>>
>> Thank you -
>> Sherri
>>
>> -Original Message-
>>> From: Sita Kakunoori 
>>> Sent: Apr 7, 2010 12:55 PM
>>> To: Sherri Novis 
>>> Cc: freesurfer@nmr.mgh.harvard.edu
>>> Subject: Re: [Freesurfer] Pial Surfaces Cutting off Gyri
>>>
>>>
>>> Hi Sherri,
>>>
>>> one of the control points seems to be in gray matter, which is probably
>>> causing this. Please try deleting it and rerunning autorecon2-cp.
>>>
>>> Sita.
>>>
>>>
>>> On Tue, 6 Apr 2010, Sherri Novis wrote:
>>>
>>>> Hello brilliant and generous FS people,
>>>>
>>>> I have introduced a problem I cannot solve.   I am simply trying to 
>>>> capture as much gray matter as possible.  We have some very bad constrast 
>>>> images (ghostly edeges where the gray matter should be).  I'm adding 
>>>> control points to try to capture - however, now when I run AR2-cp, the 
>>>> pial surfaces go haywire on the superior borders of the slices.
>>>>
>>>> Attached are two images displaying the problem.
>>>>
>>>> I have edited wm.mgz to fill in the ventricles because I was getting 
>>>> islands, and I manually edited the brainmask to remove some vasculature 
>>>> that was being included in the pial surfaces.
>>>>
>>>> Can you tell me where I introduced this instability?
>>>>
>>>> Best Regards,
>>>> Sherri
>>>
>>>
>>> The information in this e-mail is intended only for the person to whom it is
>>> addressed. If you believe this e-mail was sent to you in error and the 
>>> e-mail
>>> contains patient information, please contact the Partners Compliance 
>>> HelpLine at
>>> http://www.partners.org/complianceline . If the e-mail was sent to you in 
>>> error
>>> but does not contain patient information, please contact the sender and 
>>> properly
>>> dispose of the e-mail.
>>>
>>
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>>
>>

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Re: [Freesurfer] Pial Surfaces Cutting off Gyri

2010-04-07 Thread Sherri Novis
Thanks Sita. I have struggled with how to capture very ghostly gray matter.  
Sometimes throwing a CP in it works (I understand now this may be hosing it 
sometimes) - if AR2-cp w/CPs in white matter is not driving the pial surfaces 
to capture all the gray - is the only way to capture the ghostly gray matter to 
directly edit the pial surface?

I was trying to avoid that. I was told don't ever edit the pial surfaces - not 
sure why though.  Will manual edits of the pial surfaces cause other problems 
in getting surface segmentation stats?

Thank you -
Sherri

-Original Message-
>From: Sita Kakunoori 
>Sent: Apr 7, 2010 12:55 PM
>To: Sherri Novis 
>Cc: freesurfer@nmr.mgh.harvard.edu
>Subject: Re: [Freesurfer] Pial Surfaces Cutting off Gyri
>
>
>Hi Sherri,
>
>one of the control points seems to be in gray matter, which is probably 
>causing this. Please try deleting it and rerunning autorecon2-cp.
>
>Sita.
>
>
>On Tue, 6 Apr 2010, Sherri Novis wrote:
>
>> Hello brilliant and generous FS people,
>>
>> I have introduced a problem I cannot solve.   I am simply trying to capture 
>> as much gray matter as possible.  We have some very bad constrast images 
>> (ghostly edeges where the gray matter should be).  I'm adding control points 
>> to try to capture - however, now when I run AR2-cp, the pial surfaces go 
>> haywire on the superior borders of the slices.
>>
>> Attached are two images displaying the problem.
>>
>> I have edited wm.mgz to fill in the ventricles because I was getting 
>> islands, and I manually edited the brainmask to remove some vasculature that 
>> was being included in the pial surfaces.
>>
>> Can you tell me where I introduced this instability?
>>
>> Best Regards,
>> Sherri
>
>
>The information in this e-mail is intended only for the person to whom it is
>addressed. If you believe this e-mail was sent to you in error and the e-mail
>contains patient information, please contact the Partners Compliance HelpLine 
>at
>http://www.partners.org/complianceline . If the e-mail was sent to you in error
>but does not contain patient information, please contact the sender and 
>properly
>dispose of the e-mail.
>

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Re: [Freesurfer] Skull Stripping extra dura & vasculature

2010-02-09 Thread Sherri Novis
Thanks Bruce.  Is there anyway to address it in the intensity normalization 
phase?


-Original Message-
>From: Bruce Fischl 
>Sent: Feb 9, 2010 12:29 PM
>To: Sherri Novis 
>Cc: freesurfer@nmr.mgh.harvard.edu
>Subject: Re: [Freesurfer] Skull Stripping extra dura & vasculature
>
>Hi Sherry,
>
>that's pretty tough. The dura is very bright and quite close to the gm. 
>You may need to erase more of the dura
>
>Bruce
>
>On Tue, 9 Feb 2010, Sherri Novis 
>wrote:
>
>> Hello,
>>
>> I have a series of datasets with skull stripping issues - namely left over 
>> dura/vasculature in the occipital cortex, and some in frontal 
>> areas.(Attached is a jpeg of the type of issue.  It's pervasive throughout 
>> the slices, across a handful of subject data.)
>>
>> I have rerun skull stripping changing the watershed value, however it's not 
>> making the distinction between dura and gray matter. (recon-all -skullstrip 
>> -wsthresh [tried 0..35] -clean-bm -no-wsgcaatlas -subjid [subject_id] - FS 
>> version: freesurfer-Linux-centos4-stable-pub-v4.3.0)
>>
>> I also attempted to edit 50% of the slices by erasing voxels to make a clear 
>> boundary between the dura and cortex and then re-ran autorecon2 to see if it 
>> would at least adjust the pial surfaces - however that did not work (pial 
>> surfaces still crossed the one pixel boundary I made into the dura).
>>
>> Can you recommend any other flags or things to try before I edit/erase the 
>> excess by hand?
>>
>> Thanks for your time -
>> Sherri

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[Freesurfer] Skull Stripping extra dura & vasculature

2010-02-09 Thread Sherri Novis
Hello,

I have a series of datasets with skull stripping issues - namely left over 
dura/vasculature in the occipital cortex, and some in frontal areas.(Attached 
is a jpeg of the type of issue.  It's pervasive throughout the slices, across a 
handful of subject data.)

I have rerun skull stripping changing the watershed value, however it's not 
making the distinction between dura and gray matter. (recon-all -skullstrip 
-wsthresh [tried 0..35] -clean-bm -no-wsgcaatlas -subjid [subject_id] - FS 
version: freesurfer-Linux-centos4-stable-pub-v4.3.0)

I also attempted to edit 50% of the slices by erasing voxels to make a clear 
boundary between the dura and cortex and then re-ran autorecon2 to see if it 
would at least adjust the pial surfaces - however that did not work (pial 
surfaces still crossed the one pixel boundary I made into the dura).
 
Can you recommend any other flags or things to try before I edit/erase the 
excess by hand?

Thanks for your time -
Sherri<>___
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[Freesurfer] WM.mgz corrections in the ventricles & Individual Normalization

2010-01-19 Thread Sherri Novis
Hello -

I have two questions:

1) I noticed on wm.mgz volumes that were segmented properly, that even when the 
ventricles were 
automatically filled in, on some slices they are somewhat patchy (partially 
filled in with white, with some black/blank voxels).

Do these patchy wm fill-ins require manual fill-ins to make them entirely 
opaque?

I went through the tutorial, and it was not clear whether a patchy fill-in 
required a correction or not.

2) What is the best automated measurement that can be used to normalize an 
individual's cortical segmentation volumes for between subject comparison?  We 
have been using gray+white volumes (why we need the ventrical volume processing 
to be consistent) - but not sure if ICV would be better individual normalizer.

Thank you for your time -
Sherri
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[Freesurfer] How do Control Points and Pial Surfaces Interact?

2009-09-22 Thread Sherri Novis
Hello -

I am trying to compare normalized segmentation stats across groups.   We are 
adding control points to the white matter in an attempt to push out the pial 
surfaces when it appears grey matter has been clipped or cut short.I am 
loading the following:

tkmedit [SubjectID] brainmask.mgz lh.white -aux wm.mgz -aux-surface rh.white.

The CPs are being saved, and after running autorecon-all the CPs are referenced 
in the recon-all.log file - however the pial surfaces are not redrawn around 
the control points.

Should the white matter CPs force new pial surfaces?   Am I missing a step in 
here?

I checked the archive for the last year without luck - so I apologize if this 
is a repeat question.

Thanks much for your help -
Sherri

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[Freesurfer] Aparc Stats & Different versions of Freesurfer

2009-07-14 Thread Sherri Novis
Hello -

I am comparing aparc stats across several groups of data, and just noticed that 
recently processed groups do not have corpus callosum values...   which made me 
wonder if different versions of freesurfer will produce different aparc data...

Can aparc stats from an older version of freesurfer be compared to aparc stats 
from a more recent version?   Or do they all have to be processed with the same 
version?

Also - we noticed that the aparc areas do not extract in the same order...  is 
this also because of the different version used to process the data?  

Thanks much,
Sherri


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[Freesurfer] Details about aseg Stats

2009-06-11 Thread Sherri Novis
Hello - can anyone tell me where I can find details on what aseg stats include 
and exclude from each measurement?   The ones I need in particular are:  
Left-Cerebral-White-Matter  Left-Cerebral-Cortex and IntraCranialVol.   I'd 
like to understand if L-Cereb-Cortex means just gray matter, and/or if it 
includes ventricles & subcortical structures.   I'm also trying to find out if 
IntraCanial Volume means the space of the skull cavity, or if it means 
something different.   

Thanks much in advance -
Sherri

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