Bayesian reasoning: Given the observation of the complete identity of the 2
reports, what is the likelyhood that Bing & ChatGPT arrived at the same result
vs. the null hypothesis that Bernhard made a simple "cut & paste" mistake.
Philippe Dumas
De: "Bruno KLAHOLZ"
À: "CCP4BB"
Envoyé: V
It seems to me that it is legitimate to refer to what you describe as
"twinning". That's the difference between merohedral and non-merohedral
twinning. What you describe is non-merohedral twinning.
In fact twinning has been (re)discovered by most of the biological community
after the remarkable
Monika
Did you try ITC experiments at different temperatures ?
Delta H may be null, or close to zero, at some temperature without implying
that there is no binding !
Philippe Dumas
De: "monika chandravanshi"
À: "CCP4BB"
Envoyé: Samedi 1 Août 2020 09:57:24
Objet: [ccp4bb] Regarding diffe
I got a good advice about it: inject WhiteHouse disinfectant right into the cpu.
Good to repeat it a couple of times, but wear mask and gloves against possible
Cotrump-16-20 last attacks !
Hope it will be helpful.
Philippe Dumas
(#SupportFauci)
- Mail original -
De: "Jurgen Bosch"
À:
Relevant to the discussion:
* Cell, Vol. 110, 551–561, September 6, 2002, Copyright 2002 by Cell Press
An RNA Thermosensor Controls Expression of Virulence Genes in Listeria
monocytogenes
* Bacterial RNA thermometers: molecular zippers and switches
Jens Kortmann and Franz Narberhaus
NATURE
Dear Angshu
The answer to your question requires to define precisely the term of
"stoichiometry".
*If you consider the hexamer as "the molecule B", then the expected
stoichiometric ratio is 1/1 (one molecule A should bind to 1 hexamer B).
*But if you consider the monomer of B as "the molecule"
Dear Bernhard
I share your intuition: we should expect to observe different shapes of
titration curves depending on whether A or B2 is in the syringe (titration and
reverse titration).
I suppose that you want to test your hypothesis that, eventually, you get A2B2.
Independently of any kinetic
Le Jeudi 28 Mars 2019 12:03 CET, jai mohan
<0cab66323371-dmarc-requ...@jiscmail.ac.uk> a écrit:
A friend of mine (Angel Piñeiro) just suggested to me the "Maragoni effect",
which is likely active in the dancing droplets from Stanford and might explain
the "explosion" into separate bubbles.
Le Mercredi 27 Mars 2019 19:44 CET, Beatriz Gomes Guimaraes
a écrit:
In four days from now, I (everyone) would have taken this as a Photoshop joke...
Quite amazing! Is it reproducible?
What is the protein? Tubulin ? ::))
Philippe Dumas
> Dear all,
>
>
> I would like to share with you a surpri
Le Mardi 12 Mars 2019 19:55 CET, Dale Tronrud a écrit:
Dale
Good to have the opportunity of going back to the crystallography of the
fifties in these post-modern times...
There is an essential argumentation that should be recalled. The only reason
for the fact that one ignores low-resolution d
Le Mardi 5 Mars 2019 10:41 CET, "Roversi, Pietro (Dr.)"
a écrit:
Many years ago I did teaching on diffraction by illustrating the major aspects
of crystal structure determination with 2D crystals on 24x36 films. The crystal
was an 80x60 repeats of the famous Einstein's tongue and MIR was illu
cell, so I would also try molecular replacement
> with the ensemble of molecules you got in the small unit cell.
>
> My two cents,
> Herman
>
>
> -Ursprüngliche Nachricht-
> Von: DUMAS Philippe (IGBMC) [mailto:p.du...@ibmc-cnrs.unistra.fr]
> Gesendet: Freitag, 11
Le Vendredi 11 Janvier 2019 09:07 CET, herman.schreu...@sanofi.com a écrit:
Dear Herman,
As far as I understood the twinning problem, what you say is only true in some
occasions, and not in others.
If the "macroscopic" domains are so small that they are smaller than the X-rays
coherence length,
otein
> > (tyrosine ring). Is it possible that the hydrophobic substituent could
> > facilitate the formation of this pi-pi interaction but not necessary
> > to involve in the interaction? Thanks.
> >
> > Kind regards,
> > Wenhe
> >
> >> On Ap
Le Jeudi 26 Avril 2018 16:50 CEST, WENHE ZHONG a
écrit:
Just to be sure: how was the nM affinity evaluated ? By in vitro measurements,
or by obtaining an IC50 by tests on cells ?
Of course, if you are mentioning an IC50, you may have a measurement of the
efficacy of drug entrance in the cells
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