Garnet, Is this gene exclusive to dogs, or is it found in humans also? Sally
Garnet <garnetri...@earthlink.net> wrote: On Thu, 2004-10-21 at 00:10, David W Kenney wrote: > No...one person did go blind and almost caused DMSO to be taken off the > market totally. This all happened when they first learned of its > properties to relieve inflammation (and pain) in arthritis which is how it > was usually used. People would rub it on sore joints. It wasn't rabbits. > However since there have been few if any problems with DMSO in the last 30 > years it suggests that DMSO wasn't the etiology of the blindness anyway. Rabbits are the medical model for study eye effects of pharmaceutical agents. Problem is that they are uniquely sensitive to DMSO so are not consider a valid model for humans in this instance. Dogs too have been reported to have some occular effects with prolonged use. I still use DMSO and CS in my dogs eyes, just cleared up a case of conjunctivities in a puppy this week by spraying 20% DMSO and CS several hourly -- it cleared in less than 10 hours! I did use a bit of Gentocin ointment, maybe two applications in between the DMSO CS spray. My 5 mo old puppy was so happy when her eye stopped hurting and was obviously grateful for the assitance. > > This is much like the study of Ivomectin in animals. In the studies of > 10,000 or so dogs...1 collie died. So it is not approved for collies. > However...the average age of the whole group was higher than that expected > for the number of animals studied and the length of the study...so in effect > they could have added the wording "Extends lifespan" if they so desired and > would have been correct as far as the research was concerned. And, the > collie might well have died a natural death rather than it being caused by > the drug. This is a problem with any study, is it not? We own Australian Shepherds, a collie derived breed that sometimes exhibits this sensitivity. It is due to the MDR1 gene, and individuals with this gene are also sensitive to anesthetics, chemo therapy agents and other drugs. There is an inexpensive genetic test. Something that most well intenetioned pet owners should have done if they have a breed that is known to sometimes exhibit the effects of this gene. One certainly needs to know if a dog is sensitive to anesthetics before something comes up. Garnet -- The Silver List is a moderated forum for discussing Colloidal Silver. Instructions for unsubscribing are posted at: http://silverlist.org To post, address your message to: silver-list@eskimo.com Silver List archive: http://escribe.com/health/thesilverlist/index.html Address Off-Topic messages to: silver-off-topic-l...@eskimo.com OT Archive: http://escribe.com/health/silverofftopiclist/index.html List maintainer: Mike Devour --------------------------------- Do you Yahoo!? Yahoo! Mail - Helps protect you from nasty viruses.
