I forgot to mention the role Candida Overgrowth has in chemical sensitivity. Many are much improved if not cured by getting rid of the dysbiosis in their gut. I know I was.
Candida makes the gut wall leaky. When partically digested food enters the peritoneal cavity the body regards it as a foreign substance and responds with antibody formation and subsequent sensitivity. Garnet On Thu, 2004-10-21 at 15:58, Sally Khanna wrote: > Hmmm, this is very interesting. > > Sally > > Garnet <garnetri...@earthlink.net> wrote: > It may not be called the MDR1 or be a single gene but there is > a proven > genetic component (Irish, English Native American populations) > to > multiple chemical sensitivity which could be said, in a broad > sense to > cover this type of sensitivity. MCS is a condition with many > factors, > some of which are the porphyrin enzyme systems or lack there > of a > component to be more correct -- this is thought to be genetic, > could be > induced and also may be sex linked with women showing greater > tendencies. Also MCS relates to liver function, total load, > Kindling > (sensitivity in brain centers to molecule quantities of VOC > that access > the brain directly through the Olfactory and Trigeminal > cranial nerves > in the nasal septum, Bell et al). Also complicated by IgE > mediated Type > I Allergy, and poorly functioning or sensitized immune > systems. > > In the case of the MD! R1 gene it likely involves the ability > to > metabolize the agent. We know that sight hounds are very > sensitive to > anesthetics, however, this is due to their lack of body fat > where the > agents depot from the systemic circulation -- less body fat > means higher > blood levels. I am not sure though if they have shown a slower > metabolism in sight hounds for these agents as well. > > Garnet > > On Thu, 2004-10-21 at 11:26, Sally Khanna wrote: > > Garnet, > > > > Is this gene exclusive to dogs, or is it found in humans > also? > > > > Sally > > > > Garnet wrote: > > On Thu, 2004-10-21 at 00:10, David W Kenney wrote: > > > No...one person did go blind and almost caused DMSO to be > > taken off the > > > market totally. This all happened when they first learned > of > > its > > > properties to relieve inflammation (and pain) in arthritis > > which is how it > > > was usually used! . People would rub it on sore joints. It > > wasn't rabbits. > > > However since there have been few if any problems with > DMSO > > in the last 30 > > > years it suggests that DMSO wasn't the etiology of the > > blindness anyway. > > > > Rabbits are the medical model for study eye effects of > > pharmaceutical > > agents. Problem is that they are uniquely sensitive to DMSO > so > > are not > > consider a valid model for humans in this instance. Dogs too > > have been > > reported to have some occular effects with prolonged use. I > > still use > > DMSO and CS in my dogs eyes, just cleared up a case of > > conjunctivities > > in a puppy this week by spraying 20% DMSO and CS several > > hourly -- it > > cleared in less than 10 hours! I did use a bit of Gentocin > > ointment, > > maybe two applications in between the DMSO CS spray. My 5 mo > > old puppy > > was so happy when her eye stopped ! hurting and was > obviously > > grateful for > > the assitance. > > > > > > > > This is much like the study of Ivomectin in animals. In > the > > studies of > > > 10,000 or so dogs...1 collie died. So it is not approved > for > > collies. > > > However...the average age of the whole group was higher > than > > that expected > > > for the number of animals studied and the length of the > > study...so in effect > > > they could have added the wording "Extends lifespan" if > they > > so desired and > > > would have been correct as far as the research was > > concerned. And, the > > > collie might well have died a natural death rather than it > > being caused by > > > the drug. This is a problem with any study, is it not? > > > > We own Australian Shepherds, a collie derived breed that > > sometimes > > exhibits this sensitivity. It is due to the MDR1 gene, and > > individuals > > with this gene are also sensitive to anesthetics, chemo > > therapy agents > > and other drugs. There is an inexpensive genetic test. > > Something that > > most well intenetioned pet owners should have done if they > > have a breed > > that is known to sometimes exhibit the effects of this gene. > > One > > certainly needs to know if a dog is sensitive to anesthetics > > before > > something comes up. > > > > > > Garnet > > > > > > -- > > The Silver List is a moderated forum for discussing > Colloidal > > Silver. > > > > Instructions for unsubscribing are posted at: > > http://silverlist.org > > > > To post, address your message to: silver-list@eskimo.com > > Silver List archive: > > http://escribe.com/health/thesilverlist/index.html > > > > Address Off-Topic messages to: > > silver-off-topic-l...@eskimo.com > > OT Archive: > > http://escribe.com/health/silverofftopiclist/index.html > > > > Li! st maintainer: Mike Devour > > > > > > > ______________________________________________________________________ > > Do you Yahoo!? > > Yahoo! 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