I have always found this angle independence difficult. Why, if the anomalous scattering is truly angle-independent, don't we just put the detector at 90 or 180deg and solve the HA substructure by Patterson or direct methods using the pure anomalous scattering intensities? Or why don't we see pure "anomalous spots" at really high resolution? I think Bart Hazes' B-factor idea is right, perhaps, but I think the lack of pure anomalous intensities needs to be explained before understanding the angle-independence argument.
JPK
