If it can run PC software, then it can handle DOS disk I/O. But BIOS and/or direct hardware access may be totally incompatible.

On Tue, 27 Dec 2022, Chris via cctalk wrote:

All I can say with some certainty is this thing will read ms-dos formatted 
floppies. How else could it run ibm pc software if it didn't. The individual 
jumbo isa card-motherboards are doled out their rations internally from the 
server departmemt. No drices excwpt what tje server itself has.

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