Without going into detail, it involves power analysis, and I remember
darned little of the matrix algebra course I took years ago.

On Wednesday, February 15, 2012, Dana <dana.tier...@gmail.com> wrote:
>
> ok thanks realized after I sent the email that you were talking to Tim,
but
> i am glad to hear that I do indeed semi-remember this stuff. I m kinda
> curious about the calculation they did a thousand times if you are able to
> formulate a description. But it doesn't need to be right now. Take your
> time, and hey :) fifty words even.
>
> On Wed, Feb 15, 2012 at 6:59 PM, Larry C. Lyons <larrycly...@gmail.com
>wrote:
>
>>
>> You are not the only one. On my desk at home is a notebook with all my
>> notes for the next version of my meta-analysis application. 150 pages and
>> counting - most of which are botched formulae for calculating statistical
>> power effect sizes and converting obtained probability values to effect
>> sizes. Makes me wish at times I stayed with single case designs.
>>
>> 10 word or less that is really difficult. Can I go for 30?
>>
>> But you've essentially got the idea. I left out a lot, range estimation
and
>> correction for error andthat sort of thing, but yes.
>>
>> On Wednesday, February 15, 2012, Dana <dana.tier...@gmail.com> wrote:
>> >
>> > what not really -- the meaning of standard deviations? If so yeah you
are
>> > right, I think but what Maureen and  I said is an .... ok 10 words or
>> less
>> > version.
>> >
>> > In this case p=0.011 so theoretically if they did everything else
right,
>> > these results should replicate 99% of the time. And not, 1%.
>> >
>> > I realize that's it's not a given that the 1% is random or that it
won't
>> > occur the next time you repeat the experiment, but I think that is a
>> rather
>> > fine distinction for our purposes. Kinda like the difference between
>> > Springfield and Tyson's Corner, as seen from California, yanno? If I
>> don't
>> > have that right then fine, tell me,  but if you're going to crank up
your
>> > statistical powers I'd rather hear an explanation of that leave one out
>> > thing they did a thousand times, because that part I do not understand
at
>> > ALL.
>> >
>> > On Wed, Feb 15, 2012 at 6:21 PM, Larry C. Lyons <larrycly...@gmail.com
>> >wrote:
>> >
>> >>
>> >> Not really. It depends on the stats that are used. When looking at
>> >> statistical results, the way to interpret statistical significance is
as
>> >> follows. Let's say the researchers found the two groups showed a
>> >> significant difference of p &lt; 0.05 . This means that if you
>> replicated
>> >> the study an infinite number of times, 95% of these results would fall
>> very
>> >> close to the difference found in the first study. How meaningful that
>> >> spread is depends on the standard error of the studies, and other
>> factors.
>> >>  It also mean that in order to show a significant difference with a
>> smaller
>> >> sample you'd need a much larger difference to achieve statistical
>> >> significance.
>> >>
>> >> So you can make very accurate predictions based on fairly small
samples.
>> It
>> >> all depends on the statistical power of your experiment. I'm too
burned
>> out
>> >> to really discuss it now, but if interested Wikipedia has a pretty
good
>> >> explanation of it   - http://en.wikipedia.org/wiki/Statistical_power
>> >>
>> >> On Wednesday, February 15, 2012, LRS Scout <lrssc...@gmail.com> wrote:
>> >> >
>> >> > The sampling of 90 people is really really small.
>> >> >
>> >> > On Wed, Feb 15, 2012 at 7:29 PM, Dana <dana.tier...@gmail.com>
wrote:
>> >> >
>> >> >>
>> >> >> feel free to run away, Sam, but you still haven't showed me any
basis
>> at
>> >> >> all for the crap you've been talking.
>> >> >>
>> >> >> On Wed, Feb 15, 2012 at 4:18 PM, Sam <sammyc...@gmail.com> wrote:
>> >> >>
>> >> >> >
>> >> >> > I give up and feel the fool for not heeding this advice sooner:
>> >> >> >
>> >> >> > Don’t argue with idiots. They drag you down to their level and
beat
>> >> >> > you with experience
>> >> >> >
>> >> >> > .
>> >> >> >
>> >> >> > On Wed, Feb 15, 2012 at 7:07 PM, Dana <dana.tier...@gmail.com>
>> wrote:
>> >> >> > >
>> >> >> > >>
>> >> >> > >> Yes it is. It's the same study done three times. Two people,
90
>> >> people
>> >> >> > >> and 28 people.
>> >> >> > >>
>> >> >> > >
>> >> >> > > Ah, here's the heart of the problem. No, Sam, it isn't. It's --
>> I'd
>> >> >> call
>> >> >> > it
>> >> >> > > two studies and an experiment I guess -- that tested the same
>> >> >> hypothesis.
>> >> >> > > According to your nomenclature here, all trials for the same
drug
>> >> are a
>> >> >> > > single study. And mutually responsible for one another's
>> >> methodology.
>> >> >> > And,
>> >> >> > > according to you, everything anyone remotely affiliated with
them
>> >> may
>> >> >> > have
>> >> >> > > said in an interview...
>> >> >> > >
>> >> >> > >
>> >> >> > >> PURE BS!
>> >> >> > >> If a scientist ever made nickle form an oil company everything
>> they
>> >> >> > >> ever say for the rest of their lives is bunk in your mind.
>> >> >> > >>
>> >> >> > >
>> >> >> > > I don't recall ever saying this...  I'd get into what I might
>> have
>> >> said
>> >> >> > if
>> >> >> > > I had participated in whatever thread you are talking about,
but
>> >> let's
>> >> >> > cut
>> >> >> > > to the chase. You have no clue.  You just know you don't like
it.
>> I
>> >> >> > suppose
>> >> >> > > you're entitled to this position, but don't ask me to take it
(or
>> >> you)
>> >> >> > > seriously at this point.
>> >> >> > >
>> >> >> > > NOW, you say the science is sound even though you know it was
the
>> >> >> > >> equivalent of Bill Maher saying if you don't agree you're
>> inferior.
>> >> >> > >
>> >> >> > >
>> >> >> > > Whatever, dude, you're still talking about something that's
>> >> completely
>> >> >> > > beside the point. Concentrate on Larry's journal article. What
is
>> >> wrong
>> >> >> > >
>> with
>>
>>
>
> 

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