Hi Bruce,

Just to clarify, when you say "average the thickness along each A/P
coordinate" do you mean by looking up at the average cortical thickness of
each parcellation and then calculating their average from P->A, or is
there another way to find the average thickness of each slice and then see
how that average changes from P->A?
Thanks again for your time,
Panos

> I see. Then measure the thickness normally, then see how it changes in
> those directions. You could average the thickness along each A/P
> coordinate
> - that wouldn't be a problem. You just don't want to measure it that way
>
> cheers
> Bruce
>
>
> On Mon, 12 May 2014,
> pfot...@nmr.mgh.harvard.edu wrote:
>
>> Hi Bruce,
>>
>> Thank you for your reply. I was interested in looking how the thickness
>> changes from the posterior to the anterior side of the brain and vice
>> versa (the thickness gradient).
>>
>> Thank you again for your time!
>> Panos
>>
>>
>>> Hi Panos
>>>
>>> it would certainly be possible to make that measurement, but it
>>> wouldn't
>>> tell you anything biologically interesting. Why would you want to do
>>> such
>>> a
>>> thing? It will reflect the (arbitrary) image slice orientation and not
>>> the
>>> brain.
>>>
>>> cheers
>>> Bruce
>>>
>>>
>>> On Mon, 12 May 2014, pfot...@nmr.mgh.harvard.edu wrote:
>>>
>>>> Hi FS experts,
>>>>
>>>> I was wondering whether it would be possible to measure the average
>>>> cortical thickness at a specific slice (either axial, coronal, or
>>>> sagittal). I read in Bruce's paper: "Measuring the thickness of the
>>>> human
>>>> cerebral cortex from magnetic resonance images" that "Measuring the
>>>> thickness from the coronal slice at the point indicated by the green
>>>> cross
>>>> would result in an estimate in excess of 1 cm." Is that always the
>>>> case,
>>>> or has there been a way to bypass that issue?
>>>>
>>>> Thank you for your time,
>>>> Panos
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>>>>
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>>
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