Hi Bruce,

I see, that's really helpful, thank you!

Best,
Panos


> Hi Panos
>
> I would make an average thickness map in fsaverage space, then in matlab
> divvy up the a-p direction into bins (say 100 of them) and compute the
> average in each bin based on the a/p coordinate
>
> cheers
> Bruce
> On Tue, 13 May 2014,
> pfot...@nmr.mgh.harvard.edu wrote:
>
>> Hi Bruce,
>>
>> Just to clarify, when you say "average the thickness along each A/P
>> coordinate" do you mean by looking up at the average cortical thickness
>> of
>> each parcellation and then calculating their average from P->A, or is
>> there another way to find the average thickness of each slice and then
>> see
>> how that average changes from P->A?
>> Thanks again for your time,
>> Panos
>>
>>> I see. Then measure the thickness normally, then see how it changes in
>>> those directions. You could average the thickness along each A/P
>>> coordinate
>>> - that wouldn't be a problem. You just don't want to measure it that
>>> way
>>>
>>> cheers
>>> Bruce
>>>
>>>
>>> On Mon, 12 May 2014,
>>> pfot...@nmr.mgh.harvard.edu wrote:
>>>
>>>> Hi Bruce,
>>>>
>>>> Thank you for your reply. I was interested in looking how the
>>>> thickness
>>>> changes from the posterior to the anterior side of the brain and vice
>>>> versa (the thickness gradient).
>>>>
>>>> Thank you again for your time!
>>>> Panos
>>>>
>>>>
>>>>> Hi Panos
>>>>>
>>>>> it would certainly be possible to make that measurement, but it
>>>>> wouldn't
>>>>> tell you anything biologically interesting. Why would you want to do
>>>>> such
>>>>> a
>>>>> thing? It will reflect the (arbitrary) image slice orientation and
>>>>> not
>>>>> the
>>>>> brain.
>>>>>
>>>>> cheers
>>>>> Bruce
>>>>>
>>>>>
>>>>> On Mon, 12 May 2014, pfot...@nmr.mgh.harvard.edu wrote:
>>>>>
>>>>>> Hi FS experts,
>>>>>>
>>>>>> I was wondering whether it would be possible to measure the average
>>>>>> cortical thickness at a specific slice (either axial, coronal, or
>>>>>> sagittal). I read in Bruce's paper: "Measuring the thickness of the
>>>>>> human
>>>>>> cerebral cortex from magnetic resonance images" that "Measuring the
>>>>>> thickness from the coronal slice at the point indicated by the green
>>>>>> cross
>>>>>> would result in an estimate in excess of 1 cm." Is that always the
>>>>>> case,
>>>>>> or has there been a way to bypass that issue?
>>>>>>
>>>>>> Thank you for your time,
>>>>>> Panos
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>>>>>>
>>>>>>
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>>>>>
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