Hi Bruce,

Sorry, I had a last follow up question. I just realized that the resulting
bins will be in the fsaverage space, and hence I wouldn't be able to use
mris_anatomical_stats to calculate the average thickness of the bins,
since the fsaverage "subject" does not have a wm.mgz file. Did you have
another way in mind to calculate the thickness of each bin, or do you
believe that mris_anatomical stats should do the trick with a specific
flag?

Thanks a ton,
Panos

> Hi Bruce,
>
> I see, that's really helpful, thank you!
>
> Best,
> Panos
>
>
>> Hi Panos
>>
>> I would make an average thickness map in fsaverage space, then in matlab
>> divvy up the a-p direction into bins (say 100 of them) and compute the
>> average in each bin based on the a/p coordinate
>>
>> cheers
>> Bruce
>> On Tue, 13 May 2014,
>> pfot...@nmr.mgh.harvard.edu wrote:
>>
>>> Hi Bruce,
>>>
>>> Just to clarify, when you say "average the thickness along each A/P
>>> coordinate" do you mean by looking up at the average cortical thickness
>>> of
>>> each parcellation and then calculating their average from P->A, or is
>>> there another way to find the average thickness of each slice and then
>>> see
>>> how that average changes from P->A?
>>> Thanks again for your time,
>>> Panos
>>>
>>>> I see. Then measure the thickness normally, then see how it changes in
>>>> those directions. You could average the thickness along each A/P
>>>> coordinate
>>>> - that wouldn't be a problem. You just don't want to measure it that
>>>> way
>>>>
>>>> cheers
>>>> Bruce
>>>>
>>>>
>>>> On Mon, 12 May 2014,
>>>> pfot...@nmr.mgh.harvard.edu wrote:
>>>>
>>>>> Hi Bruce,
>>>>>
>>>>> Thank you for your reply. I was interested in looking how the
>>>>> thickness
>>>>> changes from the posterior to the anterior side of the brain and vice
>>>>> versa (the thickness gradient).
>>>>>
>>>>> Thank you again for your time!
>>>>> Panos
>>>>>
>>>>>
>>>>>> Hi Panos
>>>>>>
>>>>>> it would certainly be possible to make that measurement, but it
>>>>>> wouldn't
>>>>>> tell you anything biologically interesting. Why would you want to do
>>>>>> such
>>>>>> a
>>>>>> thing? It will reflect the (arbitrary) image slice orientation and
>>>>>> not
>>>>>> the
>>>>>> brain.
>>>>>>
>>>>>> cheers
>>>>>> Bruce
>>>>>>
>>>>>>
>>>>>> On Mon, 12 May 2014, pfot...@nmr.mgh.harvard.edu wrote:
>>>>>>
>>>>>>> Hi FS experts,
>>>>>>>
>>>>>>> I was wondering whether it would be possible to measure the average
>>>>>>> cortical thickness at a specific slice (either axial, coronal, or
>>>>>>> sagittal). I read in Bruce's paper: "Measuring the thickness of the
>>>>>>> human
>>>>>>> cerebral cortex from magnetic resonance images" that "Measuring the
>>>>>>> thickness from the coronal slice at the point indicated by the
>>>>>>> green
>>>>>>> cross
>>>>>>> would result in an estimate in excess of 1 cm." Is that always the
>>>>>>> case,
>>>>>>> or has there been a way to bypass that issue?
>>>>>>>
>>>>>>> Thank you for your time,
>>>>>>> Panos
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>>>>>>>
>>>>>>>
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>>>>>>
>>>>>>
>>>>>
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