Yes - if you've used the -bigventricles flag, you should always include it with the recon-all command.
Bram ________________________________ From: freesurfer-boun...@nmr.mgh.harvard.edu <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Matthieu Vanhoutte <matthieuvanhou...@gmail.com> Sent: Tuesday, September 18, 2018 12:45:23 PM To: Freesurfer support list Subject: Re: [Freesurfer] Troubles to determine the type of recon editing needed External Email - Use Caution Ok I will test it on normal subjects. Do I have to put this -bigventricles flag on all recon-all commands following manual editing of brainmask, white matter,...etc or just once at the first recon-all -all command ? Best, Matthieu Le mar. 18 sept. 2018 à 18:03, Bruce Fischl <fis...@nmr.mgh.harvard.edu<mailto:fis...@nmr.mgh.harvard.edu>> a écrit : I think it should be ok. It will be a bit slower, but shouldn't reduce accuracy I don't think. Try it and see Bruce On Tue, 18 Sep 2018, Matthieu Vanhoutte wrote: > > External Email - Use Caution > > Hi Bruce, > > Thanks, but in this case will recon-all with -bigventricles flag work well on > normal patients > without big ventricles ? > > Best, > Matthieu > > 2018-09-18 15:56 GMT+00:00 Bruce Fischl > <fis...@nmr.mgh.harvard.edu<mailto:fis...@nmr.mgh.harvard.edu>>: > Hi Matthieu > > yes, you will want to run all of your subjects with it > > cheers > Bruce > On Tue, 18 Sep 2018, Matthieu Vanhoutte wrote: > > > External Email - Use Caution > > Dear Bram, > > It looks like the -bigventricles flag fixed my problem with my > specific > subject. Not only, this took > into account large ventricles but also corrected grey matter > segmentation > from extra Dura tissue > that was erroneously segmented in GM. > > I understand the first point of amelioration allowed by the flag > but don't > understand where the > second point come from ? > > If I used the -bigventricles flag for all my atrophied and large > ventricles > patients and not for my > healthy patients, wouldn't it introduce a bias when further > statistically > comparing groups between > them ? > > Best, > Matthieu > > 2018-09-14 15:35 GMT+00:00 Diamond, Bram Ryder > <brdiam...@mgh.harvard.edu<mailto:brdiam...@mgh.harvard.edu>>: > If you haven't already, you may want to run the subject > through > recon-all with the > -bigventricles flag since it looks like the lateral > ventricle was > significantly > mislabeled in the aseg. If using the -bigventricles flag > doesn't fix > your problem, you > can edit the aseg.mgz manually by following the directions > in this > tutorial. Then run > the following command (again, substituting <subj_id> for > your > subject's id): > recon-all -autorecon2-noaseg -autorecon3 -subjid <subj_id> > > I would try this before doing the wm.mgz edits I suggested in my > previous > email. > > Best, > Bram > > ___________________________________________________________________________________________________ > _ > From: > freesurfer-boun...@nmr.mgh.harvard.edu<mailto:freesurfer-boun...@nmr.mgh.harvard.edu> > > <freesurfer-boun...@nmr.mgh.harvard.edu<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>> > on > behalf of Diamond, Bram Ryder > <brdiam...@mgh.harvard.edu<mailto:brdiam...@mgh.harvard.edu>> > Sent: Friday, September 14, 2018 11:07:42 AM > To: > matthieuvanhou...@gmail.com<mailto:matthieuvanhou...@gmail.com> > Cc: > freesurfer@nmr.mgh.harvard.edu<mailto:freesurfer@nmr.mgh.harvard.edu>; > astev...@nmr.mgh.harvard.edu<mailto:astev...@nmr.mgh.harvard.edu> > Subject: [Freesurfer] Troubles to determine the type of recon > editing needed > > > Hi Matthieu, > > > I've taken a look through the files you shared with us and I see > the poor > surfaces in the > posterior right hemisphere you were referring to in your message. > It looks > like your subject > has a combination of abnormally large ventricles and significant > wm > abnormalities, so I'm > surprised FreeSurfer did as well as it did. > > > As for the recon editing - I would recommend editing the wm.mgz > to more > accurately represent > the wm from slice 84 to 39. You can take a look at the white > matter edits > tutorial for details > on how to do that. Then run the following command (substituting > <subj_id> > for your > subject's id): > > > recon-all -autorecon2-wm -autorecon3 -subjid <subj_id> > > > The surface reconstruction may also benefit from labeling the > right lateral > ventricle in the > wm.mgz (as an intensity of 250) - but I'm not certain since you > didn't send > us the surfaces > for the left hemisphere. Before you do that, edit the wm.mgz as > explained in > the tutorial and > tell us how that goes. > > > All the best, > > Bram > > > Bram R. Diamond, BSc > Research Technician II > Laboratory for Computational Neuroimaging > Martinos Center for Biomedical Imaging > Massachusetts General Hospital > 149 13th Street > Charlestown, MA 02129 > (p): 617-726-6598 > > The information in this e-mail is intended only for the person to > whom it is > addressed. 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