for those who may be interested.
--- "Jonathan B. Britten" wrote:
> List,
>
> Many members know about big Pharm fraud, but few
> examples are as
> compelling at the L-Tryptophan scam, which I recall
> very, very well.
> BROJON, although being rather uneven in my opinion,
> has a great piece
> which I am pasting below.
> THE INSIDER'S STORY OF AN L-TRYPTOPHAN
> RESEARCHER
> A Response To
> Reader's Requests
>
> I have received a number of letters to the editor
> asking about which
> L-tryptophan is the best and where to buy it. Many
> readers want to
> start using it each morning to maintain their
> circadian rhythms. For
> almost 20 years it has been impossible to purchase
> L-tryptophan. So
> where did I buy my tryptophan for my research for
> the last 20 years?
>
> During the 1980's when I started my circadian rhythm
> experiments, I
> used the common L-tryptophan found in stores. I
> soon found there were
> two types --one with B6 and one without any B6. I
> tried several brands
> of each and found that the ones with B6 did not work
> at all in my
> experiments for shifting or controlling the
> circadian rhythms. Thus
> proving that B6 prevents tryptophan from getting
> into the brain. Using
> B6 will definitely disrupt your normal circadian
> rhythms.
>
> I later found that almost all the L-tryptophan in
> all brands was made
> from the same bulk raw product from Japan. The
> Showa Denko company had
> developed a method of using genetically modified
> bacteria to extract
> copious amounts of L-tryptophan from milk. Since
> the bacteria was
> removed and reused, what remained was pure, cheap
> L-tryptophan. It is
> now the same method used for making all the other
> amino acid products.
>
> In November 1989, the CDC made the false claim that
> L-tryptophan was
> causing a new disease or disorder called
> Eosinophilia Myagia Syndrome
> (EMS). The symptoms of EMS were exactly the same
> as trichinosis.
> Trichinosis is a parasite which comes from eating
> improperly cooked
> pork. My research found that about half of all
> American's have
> contracted the trichinosis parasite. But for most
> people it is
> sub-clinical, meaning most people don't even know
> that they have
> trichinosis. This sub-clinical form of the disease
> is the primary
> reason for most autoimmune disorders such as
> fibromyagia and chronic
> fatique syndrome. The body immune system attacks
> itself in an attempt
> to get rid of the parasite. The disease is caused
> by microscopic worms
> embedding by the millions into your muscles. Then
> they form a tiny
> impenetrable cyst which protects them from
> medication and from your own
> immune system. No effective medication has been
> found for ridding the
> body of trichinosis.
>
> For most people the original symptoms were a slight
> fever like the flu,
> and achy muscles as the trichinella enter the
> muscles and become
> encysted. It takes about a week and later those
> early symptoms go
> away and are forgotten. Those were exactly the same
> symptoms which
> were identified as EMS by the CDC. In the first
> week after the CDC
> alert for EMS, the doctors before reporting EMS
> needed to perform a
> trichinosis test. In the second week after the CDC
> alert, the
> trichinosis test requirement was strangely dropped,
> so all the usual
> hundreds of thousands of cases of trichinosis were
> then falsely
> reported to the CDC as the new tryptophan disorder,
> EMS.
>
> The CDC also changed the reporting requirement to
> include: observe the
> symptoms and also, secondly interview the patient
> for having previously
> or still using L-tryptophan. Thus, suddenly this
> became an
> L-tryptophan disease. But it wasn't at all. It was
> just the common
> trichinosis. I was using L-tryptophan in my
> research studies but I
> never had any symptoms. Something was very wrong
> with the CDC story
> about EMS and the ban on sales of L-tryptophan.
>
> I suspected then that this was a fraudulent story
> and I have kept in my
> files, several years worth of all the CDC reports
> and university
> research reports into the suspected causes for EMS.
> The CDC even
> blamed Showa Denko for making a contaminated product
> and forced them
> out of business. But NO cause of EMS was ever found
> and the story was
> quietly dropped, but the ban for local drug stores
> to sell L-tryptophan
> has remained. Mysteriously and quietly the ban on
> sales has been
> dropped in the last year and now many small sellers
> are using the
> Internet to push L-tryptophan. Why? What has
> suddenly changed?
>
> The original reason for banning the sale of
> L-tryptophan is still a
> mystery. I suspected the illegal ban was bought and
> paid for by Eli
> Lilly which made nearly a trillion dollars by
> selling Prozac, which was
> designed to replace L-tryptophan as a means to raise
> the level of
> serotonin in the brain. Of course the reason for
> the "brain chemical
> imbalance" or low level of serotonin in the first
> place was the
> over-abundance of B6 in the diet which eliminates
> L-tryptophan from the
> body. That strange relationship is why I have
> studied and done
> experiments with both L-tryptophan and B6 for the
> last 20 years.
>
> Right after the sales ban in November 1989, I looked
> for alternate
> sources for L-tryptophan. I did find a source, a
> company called BIOS
> Biochemical, which was continuing to sell
> L-tryptophan, not for people,
> but to farmers who added the product to cattle feed.
> Since about 10
> percent of the protein in cow's or mother's milk is
> tryptophan, by
> adding L-T to the dairy feed, the farmers could
> increase the milk
> output from their cows. Adding $5 worth of
> tryptophan to the dairy
> feed would increase the milk output by about $500
> over the life of the
> dairy cow. Such a deal for the farmer on such a
> small investment.
>
> The BIOS Biochemical product was also USP quality so
> it was certified
> for purity and content -- even though the product
> was clearly marked
> "For Veterinary Use Only." Just ignore that. That
> was to get around
> the CDC ban. L-tryptophan from cows milk or
> mother's milk is exactly
> the same. If the CDC wanted to completely ban
> L-tryptophan they would
> have needed to outlaw breast feeding. And that's
> never going to
> happen. Also L-tryptophan, when it was packaged
> with other amino acids
> and vitamins such as B6 was never banned for sale.
> Is that mysterious
> or what?
>
> At that time, BIOS was the only source I found for
> tryptophan and it
> was online in 1990, which was just a few years
> before the Internet. In
> those days, to be online meant you had an account
> with Compuserve, AOL
> or smaller sites such as Mindspring. AOL actually
> let you create your
> own "homepage" or "webpage" which since than has
> grown from several
> hundreds of pages to multiple billions of websites.
> I have been using
> BIOS Biochemicals for 16 years. For cattle feed,
> the company sells
> L-tryptophan in large bags or bulk containers by the
> multiple pound.
> They also sell the powder in 500mg capsules. I had
> been using 250 to
> 500mg capsules before 1989. I figured that the
> cattle farmers are not
> stuffing capsules in the mouths of their cattle, so
> the only purpose of
> the capsules must be for human use.
>
> Thus, BIOS must have known that their biggest L-T
> market was tryptophan
> for humans who did not believe the CDC's EMS hoax
> story. Prior to the
> CDC ban, about 30 million Americans had been using
> L-tryptophan for a
> variety of problems, mostly circadian rhythm
> disorders. Most of these
> people were later diagnosed as "brain chemical
> disorder" and were put
> on Eli Lilly's Prozac. Thus Lilly already had a
> huge ready-made market
> for their Prozac. But instead of a 20-cent
> L-tryptophan capsule each
> day, the people were paying $20 or more per day for
> Prozac -- which
> supposedly did the same thing.
>
> Since BIOS has also sold its L-T in large bags since
> before the 1980's,
> I assume that most of all the other small marketers
> who now sell
> L-tryptophan online are simply buying the big bulk
> bags from BIOS and
> then repackaging it into small capsules. Since it
> costs a lot of money
> to get a product USP certified, it seems only
> natural that all the
> smaller tryptophan companies now selling on the
> Internet are getting
> their USP certified product simply by buying the raw
> product in bulk
> from BIOS. What that means is that it doesn't
> matter which brand or
> source you use for USP L-tryptophan -- because they
> are all the same
> -- they all come in bulk from BIOS Biochemicals.
>
> If you search on Google for buying L-tryptophan you
> will get many pages
> for marketers of USP L-tryptophan. Way down on the
> 4th or 5th page you
> find BIOS. The reason is because BIOS doesn't need
> to advertise their
> product. They ARE the source, and everybody else is
> selling their
> product. BIOS doesn't need to compete with its own
> distributers.
>
> Based on that information, I have been buying
> directly from the source
> for the last 16 years. If you find something better
> let me know. I
> don't work for BIOS, so I am not selling or
> promoting their product. I
> just use it.
>
> And what about the strange mystery of why it has
> suddenly become so
> easy to buy L-tryptophan? Maybe it is just strange
> coincidence (I
> don't believe in strange coincidences), but two
> years ago the Eli Lilly
> international drug patent ran out. Numerous other
> pharmaceutical
> companies are now making generic Prozac, not for $20
> per dose, but for
> about a dollar a dose. So Prozac is no longer a big
> profit item. The
> Prozac era has come to an end. There is no longer a
> need to eliminate
> the competition from 50 cent L-tryptophan. Since
> nobody is now pushing
> for a ban on L-tryptophan to keep competitors off
> the market, it has
> suddenly become very easy to purchase it, but still
> it is not being
> stocked in stores. So buying online is still the
> best bet. But that
> does explain the mysterious and sudden easing of the
> ban on
> L-tryptophan. Could the 19-year ban on the sales of
> L-tryptophan be
> called a huge billion dollar Big Pharma fraud? You
> betcha. And
> similar such frauds are continuing today.
>
> But if you doctor is still suggesting you use Prozac
> or Zoloft or any
> of the other similar SSRI's consider this. If you
> take L-tryptophan in
> the morning it produces serotonin in the brain, and
> raises the brain
> temperature and wakes you up. If you take
> L-tryptophan in the evening
> it produces melatonin in the brain, which lowers the
> brain temperature
> and induces sleep. This operates the daily cycle of
> your circadian
> rhythms.
>
> If, instead, you take Prozac in the morning, it
> raises your brain
> temperature, and works something like an
> anti-depressant. But if you
> take Prozac with an evening meal, as prescribed by
> some doctors, it
> will still raise your brain temperature and keep you
> awake all night
> long. One of the most common reported side-effects
> of Prozac or the
> other SSRI's is insomnia or circadian rhythm
> disorders. It only works
> as an anti-depressant if you take it first thing in
> the morning. But
> if instead, you take L-tryptophan at any time of
> day, it automatically
> converts to serotonin or melatonin depending on the
> time of day when
> you take it. It works automatically to run your
> circadian rhythms, you
> can't overdose and there are no side-effects such as
> insomnia. But for
> "Tryptophan Pumping" is still works best if you take
> it first thing in
> the morning. That's how you get optimum and
> quickest results.
>
> If you want to do your own circadian rhythm
> experiments, go here:
> BIOS Biochemicals
> www.biochemicals.com
>
> If you find this information is valuable, post a
> copy of this to the
> Internet and let everyone know about it. Also tell
> your friends that
> they can sign up for the BroJon Digest to get the
> latest research about
> circadian rhythms, as it is published. Or go to the
> BroJon Gazette to
> read all the stories in the "B6 Bomber" series.
>
> Marshall Smith
> Editor, Brother Jonathan Gazette
> newsedi...@brojon.com
>
> Click here to find the live links to the full
> stories in the Gazette -
> http://www.brojon.com
>
>
> KBB
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