Re: [Freesurfer] within-subject contrast between runs

2020-03-11 Thread Milde, Christopher
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Dear Mr. Greve


Thanks for your suggestions.


However I'm still a bit puzzled about how to contrast two runs corresponding to 
different stimulations (StimA: runA and StimB:runB) from one subject.

I have two runs each containing a paradigm file corresponding to one of the two 
stimulations.

How is it possible to contrast those two stimulation conditions acquired in two 
different runs since one run and thus also the paradigm file does not contain 
both stimulation conditions?

Seemingly both stimulation conditions must be in one paradigm file set to 
different onset timings to perform mkcontrast-sess


My folder Structure is as follows

Project Name

Session = Subject

Runs (001, 002) = Stimulation A and Stimulation B, each with a separate 
paradigm file


I know that I do not have to model the no-stimulation periods explicitely


Best wishes

Chris


Von: freesurfer-boun...@nmr.mgh.harvard.edu 
 im Auftrag von Douglas N. Greve 

Gesendet: Freitag, 6. März 2020 17:54:16
An: freesurfer@nmr.mgh.harvard.edu
Betreff: Re: [Freesurfer] within-subject contrast between runs



On 3/6/2020 11:15 AM, Milde, Christopher wrote:

External Email - Use Caution

Dear Freesurfer Experts,


I have a very basic questions about creating subject-wise contrasts between runs



Background

Study with two runs per subject where each run corresponds two a different 
condition (i.e. Stimulation A (on - off) and Stimulation B (on - off).

I performed the preprocessing and 1st levels stats in the native subjects space


Questions

  *   How can I obtain a within-subjects contrast between two runs (the 
Stimulation A vs. Stimulation B )  obtained in two runs within one session?

The easiest way is to code the conditions differently in the paradigm file (eg, 
instead of two conditions, you'd have 4, ARun1, BRun1, ARun2, BRun2), then just 
create contrasts as normal

  *   Can I obtain this within-subject contrast by staying in the native 
subject space?

It can be done in fsaverage or the native subject surface space, it is not 
related.

  *   Do I have to concatenate both runs and create a new parradigm file?

No, see above


Thanks for your support


Sincerely

Chris





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[Freesurfer] within-subject contrast between runs

2020-03-06 Thread Milde, Christopher
External Email - Use Caution

Dear Freesurfer Experts,


I have a very basic questions about creating subject-wise contrasts between runs



Background

Study with two runs per subject where each run corresponds two a different 
condition (i.e. Stimulation A (on - off) and Stimulation B (on - off).

I performed the preprocessing and 1st levels stats in the native subjects space


Questions

  *   How can I obtain a within-subjects contrast between two runs (the 
Stimulation A vs. Stimulation B )  obtained in two runs within one session?
  *   Can I obtain this within-subject contrast by staying in the native 
subject space?
  *   Do I have to concatenate both runs and create a new parradigm file?


Thanks for your support


Sincerely

Chris


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[Freesurfer] Definition of circular label centered on peak vertex

2018-10-05 Thread Milde, Christopher
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Dear FS experts


I`m interested in extracting beta values from a FSFAST analysis performed in 
the subject`s native space. The beta values shall be extracted from a circular 
label around the peak vertex.


How can you define a circular label centered on the peak to extract average 
stats (e.g. betas) from that label?


I`m aware how to create mask from the whole clusters in a given ROI saving them 
as labels and extracting stats. However I`m not sure how to define a circular 
mask or label.


Thanks in advance

Chris
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[Freesurfer] epidewarp.fsl radian phase range error

2016-06-02 Thread Milde, Christopher
Dear FS experts,

I also encountered this problem when trying to apply epidewarp.fsl:

ERROR: input phase image exceeds allowable phase range.
Allowable range is 6.283 radians.  Image range is: 12.5633 radians

I read that there is an updated version of epidewarp.fsl which might solve this 
problem. Can I rescale the phase images?

I appreciated any support.

Best,

Christopher
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[Freesurfer] interhemispheric registration in native space

2015-12-13 Thread Milde, Christopher


Dear Freesurfer experts,



is there a way to perform an interhemispheric registration with rh, lh surfaces 
in native space?

Preferentially, I would perform the registration with smoothwm surfaces.



I only found the xhemi command which refers to fsaverage as a target



Best wishes,



Christopher


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Re: [Freesurfer] mri_vol2surf nii.gz to .mgh conversion

2015-07-03 Thread Milde, Christopher
Basically, I try to create the .mgh files from sig.nii.gz and ces.nii.gz files 
needed for mri_segstats in ROI-analysis.

I run already preprocessing and selxavg3-sess stats to produce the different 
stats files (sii/ces.nii.gz)

The .mgh files show the correct anatomy-space dimension (mri_info: 1x1x1 mm; 
256^3, beforehand surface dimension 141526 x 1 x 1) but seem to be corrupted. I 
tried to visualize the whole hemisphere sig.nii.gz converted into sig.mgh but 
now activations show up despite of highly significant activations visible in 
the sig.nii.gz


To create .mgh files and run the ROI-analysis, I used the following commands:

### resample ces.nii volume to anatomical space
#1 resample ces.nii.gz to anatomy
mri_vol2vol --mov $sub/bold/EX.sm5.lh/EX/ces.nii.gz --reg 
$sub/bold/001/register.dof6.dat --fstarg --interp nearest -- o 
$sub/bold/EX.sm5.lh/EX/ces.lh.mgh

#2 resample sig.nii.gz to anatomy
mri_vol2vol --mov $sub/bold/EX.sm5.lh/EX/sig.nii.gz --reg 
$sub/bold/001/register.dof6.dat  --fstarg --interp nearest  --o 
$sub/bold/EX.sm5.lh/EX/sig.lh.mgh

#3 run ROI with an unsigned functional constraint
mri-segstats --seg $SUBJECTS_DIR/$sub/mri/aparc+aseg.mgz --ctab 
$FREESURFER_HOME/FreeSurferColorLUT.txt --id 410 -id 407 --i 
$sub/bold/EX.sm5.lh/EX/ces.lh.mgh --maskthresh 2 --masksign abs

The ROI analysis always ends up with zero hrf-amplitudes.

I appreciate your support,

Christopher







-Ursprüngliche Nachricht-
Von: freesurfer-boun...@nmr.mgh.harvard.edu 
[mailto:freesurfer-boun...@nmr.mgh.harvard.edu] Im Auftrag von Douglas N Greve
Gesendet: Donnerstag, 2. Juli 2015 17:18
An: freesurfer@nmr.mgh.harvard.edu
Betreff: Re: [Freesurfer] mri_vol2surf nii.gz to .mgh conversion

Sorry, can you backup and tell me what you are trying to accomplish?
doug

On 07/02/2015 10:05 AM, Milde, Christopher wrote:
 Dear Doug,

 thanks for the  immediate response. Actually I checked  the 
 registration with freeview/tkregister2 and print out the quality 
 values which are perfectly fine

 I did the following fMRI-analysis steps

 FSFAST
 1. Preproc-sess (for smoothwm as well as fsaverage space)  -- 
 register.dof6.dat in bold/001 and bold/002 folders 2. Selxavg-sess on 
 created design matrices and contrasts (one of the 1st-level stat files 
 is called EX.sm5.lh)

 3. And  interrogated the results with mris_surfcluster (EX.sm5.lh/EX/ 
 includes the sig.nii ces.nii as well as txt.files with the 
 mris_surfcluster output)


 The main problem is the creation of .mgh files as inputs used for 
 ROI-analysis in the mri_segstats cmd. So the conversion of the sig.nii 
 ces.nii into sig.mgh and ces.mgh (using mri_vol2vol) 
 https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/MultiModalFmriInd
 ividual_freeview

 How to transfer the surface nii.gz files into .mgh files used in volume space?

 Thanks,

 Christopher



 -Ursprüngliche Nachricht-
 Von: freesurfer-boun...@nmr.mgh.harvard.edu 
 [mailto:freesurfer-boun...@nmr.mgh.harvard.edu] Im Auftrag von Douglas 
 N Greve
 Gesendet: Donnerstag, 2. Juli 2015 14:49
 An: freesurfer@nmr.mgh.harvard.edu
 Betreff: Re: [Freesurfer] mri_vol2surf nii.gz to .mgh conversion

 How did you create the EX.sm5.lh analysis? It is probably the case that it is 
 already on the surface in which case you don't need to run vol2surf.
 doug

 On 07/02/2015 04:54 AM, Milde, Christopher wrote:
 Dear Freesurfers,

 I have problems converting .nii.gz files into .mgh files needed e.g.
 for performing ROI analysis.

 I used mri_vol2surf and mri_vol2vol to produce .mgh files either to 
 visualize contrast estimates and significance maps on volumes or 
 surfaces

 I think the problem is due to voxel resolution mismatches between 
 source and registration files but I don't know how to solve this problem.

 I worked with different registration files: the register.dof6.dat 
 (originally outpu from the preproc-sess) as well as register.dat and 
 register.lta by running bbregister for the template.nii.gz


 -
 -
 -
 here is an example command:

 # resample to surface

 mri_vol2surf --mov $sub/bold/EX.sm5.lh/EX/sig.nii.gz --reg 
 $sub/bold/register.lta --projfrac 0.5 \  --interp nearest --hemi lh 
 --o $sub/bold/lh.sig.mgh


 mri_vol2surf --mov $sub/bold/EX.sm5.lh/EX/sig.nii.gz --reg 
 $sub/bold/register.lta --projfrac 0.5 \
   --interp nearest --hemi lh --o $sub/bold/lh.sig.mgh
 srcvol = PM_04001/bold/EX.sm5.lh/EX/sig.nii.gz
 srcreg = PM_04001/bold/register.lta
 srcregold = 0
 srcwarp unspecified
 surf = white
 hemi = lh
 ProjFrac = 0.5
 thickness = thickness
 reshape = 0
 interp = nearest
 float2int = round
 GetProjMax = 0
 INFO: float2int code = 0
 Done loading volume
 regio_read_register: loading lta
 reading extra input line subject PM_04001 reading extra input line 
 fscale 0.15
 WARNING: the voxel resolution in the source volume (1,1,1) differs
   from

[Freesurfer] mri_vol2surf nii.gz to .mgh conversion

2015-07-02 Thread Milde, Christopher
Dear Freesurfers,

I have problems converting .nii.gz files into .mgh files needed e.g. for 
performing ROI analysis.

I used mri_vol2surf and mri_vol2vol to produce .mgh files either to visualize 
contrast estimates and significance maps on volumes or surfaces

I think the problem is due to voxel resolution mismatches between source and 
registration files but I don't know how to solve this problem.

I worked with different registration files: the register.dof6.dat (originally 
outpu from the preproc-sess) as well as register.dat and register.lta by 
running bbregister for the template.nii.gz


---
here is an example command:

# resample to surface

mri_vol2surf --mov $sub/bold/EX.sm5.lh/EX/sig.nii.gz --reg 
$sub/bold/register.lta --projfrac 0.5 \
 --interp nearest --hemi lh --o $sub/bold/lh.sig.mgh


mri_vol2surf --mov $sub/bold/EX.sm5.lh/EX/sig.nii.gz --reg 
$sub/bold/register.lta --projfrac 0.5 \
  --interp nearest --hemi lh --o $sub/bold/lh.sig.mgh
srcvol = PM_04001/bold/EX.sm5.lh/EX/sig.nii.gz
srcreg = PM_04001/bold/register.lta
srcregold = 0
srcwarp unspecified
surf = white
hemi = lh
ProjFrac = 0.5
thickness = thickness
reshape = 0
interp = nearest
float2int = round
GetProjMax = 0
INFO: float2int code = 0
Done loading volume
regio_read_register: loading lta
reading extra input line subject PM_04001
reading extra input line fscale 0.15
WARNING: the voxel resolution in the source volume (1,1,1) differs
 from that listed in the registration file (2.29167,2.29167,2.99)
Reading surface /home/christopher/subjects/PM_04001/surf/lh.white
Done reading source surface
Reading thickness /home/christopher/subjects/PM_04001/surf/lh.thickness
Done
Mapping Source Volume onto Source Subject Surface
 1 0.5 0.5 0.5
using old
Done mapping volume to surface
Number of source voxels hit = 5
Writing to PM_04001/bold/lh.sig.mgh
Dim: 126553 1 1



Thanks,

Christopher
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Re: [Freesurfer] mri_vol2surf nii.gz to .mgh conversion

2015-07-02 Thread Milde, Christopher
Dear Doug,

thanks for the  immediate response. Actually I checked  the registration with 
freeview/tkregister2 and print out the quality values which are perfectly fine 

I did the following fMRI-analysis steps

FSFAST
1. Preproc-sess (for smoothwm as well as fsaverage space)  -- 
register.dof6.dat in bold/001 and bold/002 folders
2. Selxavg-sess on created design matrices and contrasts (one of the 1st-level 
stat files is called EX.sm5.lh)

3. And  interrogated the results with mris_surfcluster (EX.sm5.lh/EX/ includes 
the sig.nii ces.nii as well as txt.files with the mris_surfcluster output)


The main problem is the creation of .mgh files as inputs used for ROI-analysis 
in the mri_segstats cmd. So the conversion of the sig.nii ces.nii into sig.mgh 
and ces.mgh (using mri_vol2vol)
https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/MultiModalFmriIndividual_freeview

How to transfer the surface nii.gz files into .mgh files used in volume space?

Thanks,

Christopher



-Ursprüngliche Nachricht-
Von: freesurfer-boun...@nmr.mgh.harvard.edu 
[mailto:freesurfer-boun...@nmr.mgh.harvard.edu] Im Auftrag von Douglas N Greve
Gesendet: Donnerstag, 2. Juli 2015 14:49
An: freesurfer@nmr.mgh.harvard.edu
Betreff: Re: [Freesurfer] mri_vol2surf nii.gz to .mgh conversion

How did you create the EX.sm5.lh analysis? It is probably the case that it is 
already on the surface in which case you don't need to run vol2surf.
doug

On 07/02/2015 04:54 AM, Milde, Christopher wrote:
 Dear Freesurfers,

 I have problems converting .nii.gz files into .mgh files needed e.g. 
 for performing ROI analysis.

 I used mri_vol2surf and mri_vol2vol to produce .mgh files either to 
 visualize contrast estimates and significance maps on volumes or 
 surfaces

 I think the problem is due to voxel resolution mismatches between 
 source and registration files but I don't know how to solve this problem.

 I worked with different registration files: the register.dof6.dat 
 (originally outpu from the preproc-sess) as well as register.dat and 
 register.lta by running bbregister for the template.nii.gz


 --
 -
 here is an example command:

 # resample to surface

 mri_vol2surf --mov $sub/bold/EX.sm5.lh/EX/sig.nii.gz --reg 
 $sub/bold/register.lta --projfrac 0.5 \  --interp nearest --hemi lh 
 --o $sub/bold/lh.sig.mgh


 mri_vol2surf --mov $sub/bold/EX.sm5.lh/EX/sig.nii.gz --reg 
 $sub/bold/register.lta --projfrac 0.5 \
   --interp nearest --hemi lh --o $sub/bold/lh.sig.mgh
 srcvol = PM_04001/bold/EX.sm5.lh/EX/sig.nii.gz
 srcreg = PM_04001/bold/register.lta
 srcregold = 0
 srcwarp unspecified
 surf = white
 hemi = lh
 ProjFrac = 0.5
 thickness = thickness
 reshape = 0
 interp = nearest
 float2int = round
 GetProjMax = 0
 INFO: float2int code = 0
 Done loading volume
 regio_read_register: loading lta
 reading extra input line subject PM_04001 reading extra input line 
 fscale 0.15
 WARNING: the voxel resolution in the source volume (1,1,1) differs
  from that listed in the registration file 
 (2.29167,2.29167,2.99) Reading surface 
 /home/christopher/subjects/PM_04001/surf/lh.white
 Done reading source surface
 Reading thickness 
 /home/christopher/subjects/PM_04001/surf/lh.thickness
 Done
 Mapping Source Volume onto Source Subject Surface
  1 0.5 0.5 0.5
 using old
 Done mapping volume to surface
 Number of source voxels hit = 5
 Writing to PM_04001/bold/lh.sig.mgh
 Dim: 126553 1 1

 --
 --

 Thanks,

 Christopher


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--
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gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/

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[Freesurfer] Vertex Index to Vertex RAS withouth using surface visualizer (tksurfer or tkmedit)

2015-06-29 Thread Milde, Christopher
Dear FS experts

I extracted the vertex indices of several subjects. But unfortunately I did not 
extract the corresponding Vertex RAS values. Is there a command to translate 
the Vertex Index into a Vertex RAS so that I do not have to scroll through all 
the subjects again?

I would like to script the translation from Vertex Index to Vertex RAS

Best wishes,

Christopher
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[Freesurfer] computing cluster overlap

2015-06-19 Thread Milde, Christopher
Dear Freesurfer-Experts,

I'm looking for an elegant way of computing degree of overlap between activated 
clusters within-subject and between sessions (transversal) on the smoothwm.

I thought about running a conjunction analysis between the sessions to detect 
the extents of common activations, but maybe there are much better ways?

I'm thankful for any advice,

Best wishes,

Christopher


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[Freesurfer] missing files in fsaverage folder

2015-04-22 Thread Milde, Christopher
Dear Freesurfer Experts,

is there an easy way to update only folders within the Freesurfer folder? 
Accidentally, I deleted the fsaverage folder from the Freesurfer version. I 
copied the fsaverage folder from another Freesurfer installation. But seemingly 
some essential files (e.g. perirhinal label) are missing because of different 
FS versions.
Due to some missing files in fsaverage some commands do not run.

Furthermore, I cannot find some tools like stxgrinder-sess or func2roi-sess 
within the FSFAST package. So, is there an easy way to make an update?

Info: I’m using Freesurfer v5.3.0 for Linux-centos4

I’m thankful for any advice,

Cheers,

Chris


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Re: [Freesurfer] multiple comparisons correction for individual hemispheres (native space)

2014-12-11 Thread Milde, Christopher
Dear Doug,

Unfortunately, it doesn't make a difference if I'm using a dot or comma or 
simply type in 2 or 3 as a threshold. The terminal output always shows me the 
converted version with a comma 2.3 -- 2,3 or 2 -- 2,0 which is not recognized 
by the command. 

Maybe I have to change the default settings of floats in the bash using printf?

Sincerely yours,

Christopher

-Ursprüngliche Nachricht-
Von: freesurfer-boun...@nmr.mgh.harvard.edu 
[mailto:freesurfer-boun...@nmr.mgh.harvard.edu] Im Auftrag von Douglas N Greve
Gesendet: Mittwoch, 10. Dezember 2014 17:31
An: freesurfer@nmr.mgh.harvard.edu
Betreff: Re: [Freesurfer] multiple comparisons correction for individual 
hemispheres (native space)


Are you using 1.3 or 1,3 ?

On 12/09/2014 03:10 AM, Milde, Christopher wrote:
 Dear Doug,

 I tried to run MCC with cluster-sess but unfortunately I got the same error 
 message like when I'm using mri_glmfit-sim.
 It does not recognize the thresh (cluster-forming thresh)

 Here is the terminal output:

 Setting up environment for FreeSurfer/FS-FAST (and FSL)
 FREESURFER_HOME   /home/christopher/Desktop/freesurfer
 FSFAST_HOME   /home/christopher/Desktop/freesurfer/fsfast
 FSF_OUTPUT_FORMAT nii.gz
 SUBJECTS_DIR  /home/christopher/Desktop/freesurfer/subjects
 MNI_DIR   /home/christopher/Desktop/freesurfer/mni
 FSL_DIR   /usr/local/fsl
 [christopher@fu20a S1]$ proj_dir=/home/christopher/Desktop/freesurfer/S1
 [christopher@fu20a S1]$ cd $proj_dir
 [christopher@fu20a S1]$
 [christopher@fu20a S1]$ cluster-sess -s PM_02540 -c stim_DL -analysis 
 DL.sm5.rh -thresh 1.3 -cwp .05 -sign pos
 ERROR: thresh = 1,3, must be 1.3, 2.0, 2.3, 3.0, 3.3, 4.0

 Sincerely yours,

 Christopher



 -Ursprüngliche Nachricht-
 Von: freesurfer-boun...@nmr.mgh.harvard.edu 
 [mailto:freesurfer-boun...@nmr.mgh.harvard.edu] Im Auftrag von Douglas N Greve
 Gesendet: Montag, 24. November 2014 20:34
 An: freesurfer@nmr.mgh.harvard.edu
 Betreff: Re: [Freesurfer] multiple comparisons correction for individual 
 hemispheres (native space)


 Hi Christopher, sorry for the delay. I had a write a new program. You can 
 download it from here 
 ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/cluster-sess
 Let me know how it goes

 doug

 On 11/14/2014 06:05 AM, Milde, Christopher wrote:
 Dear Freesurfer experts,

 I performed fMRI analysis using FSFast resulting in uncorrected significance 
 maps (fsig.nii.gz). For selxavg3-sess I did not use the -fwhm flag (I rerun 
 selxavg3-sess with -fwhm at moment).

 How can I use simulations for native space hemispheres?. I tried to adapt 
 mri_glmfit-sim but unfortunately it failed...

 Sincerely yours,

 Christopher

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gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
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Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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Re: [Freesurfer] multiple comparisons correction for individual hemispheres (native space)

2014-12-09 Thread Milde, Christopher
Dear Doug,

I tried to run MCC with cluster-sess but unfortunately I got the same error 
message like when I'm using mri_glmfit-sim. 
It does not recognize the thresh (cluster-forming thresh)

Here is the terminal output:

Setting up environment for FreeSurfer/FS-FAST (and FSL)
FREESURFER_HOME   /home/christopher/Desktop/freesurfer
FSFAST_HOME   /home/christopher/Desktop/freesurfer/fsfast
FSF_OUTPUT_FORMAT nii.gz
SUBJECTS_DIR  /home/christopher/Desktop/freesurfer/subjects
MNI_DIR   /home/christopher/Desktop/freesurfer/mni
FSL_DIR   /usr/local/fsl
[christopher@fu20a S1]$ proj_dir=/home/christopher/Desktop/freesurfer/S1
[christopher@fu20a S1]$ cd $proj_dir
[christopher@fu20a S1]$ 
[christopher@fu20a S1]$ cluster-sess -s PM_02540 -c stim_DL -analysis DL.sm5.rh 
-thresh 1.3 -cwp .05 -sign pos
ERROR: thresh = 1,3, must be 1.3, 2.0, 2.3, 3.0, 3.3, 4.0

Sincerely yours,

Christopher



-Ursprüngliche Nachricht-
Von: freesurfer-boun...@nmr.mgh.harvard.edu 
[mailto:freesurfer-boun...@nmr.mgh.harvard.edu] Im Auftrag von Douglas N Greve
Gesendet: Montag, 24. November 2014 20:34
An: freesurfer@nmr.mgh.harvard.edu
Betreff: Re: [Freesurfer] multiple comparisons correction for individual 
hemispheres (native space)


Hi Christopher, sorry for the delay. I had a write a new program. You can 
download it from here 
ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/cluster-sess
Let me know how it goes

doug

On 11/14/2014 06:05 AM, Milde, Christopher wrote:
 Dear Freesurfer experts,

 I performed fMRI analysis using FSFast resulting in uncorrected significance 
 maps (fsig.nii.gz). For selxavg3-sess I did not use the -fwhm flag (I rerun 
 selxavg3-sess with -fwhm at moment).

 How can I use simulations for native space hemispheres?. I tried to adapt 
 mri_glmfit-sim but unfortunately it failed...

 Sincerely yours,

 Christopher

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 Freesurfer@nmr.mgh.harvard.edu
 https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer



--
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MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/

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[Freesurfer] multiple comparisons compensation for first-level analysis

2014-11-19 Thread Milde, Christopher
Dear Freesurfer experts,

I'm not sure how to apply cluster-wise correction for multiple comparisons when 
one is not interested in doing group statistics.

For group analysis you concatenate individuals into one file and use mri_glmfit 
and mri_glmfit-sim to run general linear model and simulations.

I want to apply multiple comparisons only within the individual subjects (stay 
at first-level), so that I don't have glm directories created by mri_glmfit.

I ran recon-all with -qcache, so I have pre-computed MC simulations.
I used the -fwhm option during selxavg3-sess to estimate smoothness.

è pre-cached  simulation

I have fMRI-data.


Do you have any suggestions?

Sincerely yours,

Christopher

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[Freesurfer] multiple comparisons correction for individual hemispheres (native space)

2014-11-14 Thread Milde, Christopher

Dear Freesurfer experts,

I performed fMRI analysis using FSFast resulting in uncorrected significance 
maps (fsig.nii.gz). For selxavg3-sess I did not use the -fwhm flag (I rerun 
selxavg3-sess with -fwhm at moment).

How can I use simulations for native space hemispheres?. I tried to adapt 
mri_glmfit-sim but unfortunately it failed...

Sincerely yours,

Christopher

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dispose of the e-mail.



[Freesurfer] mkanalysis-sess blocked design

2014-09-03 Thread Milde, Christopher
Dear Freesurfer Experts,

I want to run mkanalysis-sess for a blocked design, but unfortunately only the 
flags -abblocked, -event-related, -retinotopy and -notask do exist.
How can I specify the designtype for a blocked design with one condition and on 
fixation with different block lengths for condition and fixation?
I'm using Freesurfer 5.3

Thanks in advance,

Chris

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Re: [Freesurfer] mkanalysis-sess blocked design

2014-09-03 Thread Milde, Christopher
I solved the problem. I figured out that the event-related flag also refers to 
blocked-designs

Best wishes

Chris

Von: freesurfer-boun...@nmr.mgh.harvard.edu 
[mailto:freesurfer-boun...@nmr.mgh.harvard.edu] Im Auftrag von Milde, 
Christopher
Gesendet: Mittwoch, 3. September 2014 14:12
An: freesurfer@nmr.mgh.harvard.edu
Betreff: [Freesurfer] mkanalysis-sess blocked design

Dear Freesurfer Experts,

I want to run mkanalysis-sess for a blocked design, but unfortunately only the 
flags -abblocked, -event-related, -retinotopy and -notask do exist.
How can I specify the designtype for a blocked design with one condition and on 
fixation with different block lengths for condition and fixation?

I'm using Freesurfer 5.3

Thanks in advance,

Chris

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Re: [Freesurfer] 3dvolreg.afni error during mc-sess

2014-08-28 Thread Milde, Christopher
Dear Doug,

Finally, I was able to solve the 3dvolreg.afni error problem. I installed the 
recent AFNI version for Linux and replaced the 3dvolreg file in Freesurfer/bin 
by the AFNI 3dvolreg.afni of the AFNI software package. After adding the Suffix 
.afni  (the AFNI-3dvolreg file doesn't end with .afni) the mc-sess runs well.

Best wishes,

Christopher

-Ursprüngliche Nachricht-
Von: freesurfer-boun...@nmr.mgh.harvard.edu 
[mailto:freesurfer-boun...@nmr.mgh.harvard.edu] Im Auftrag von Douglas N Greve
Gesendet: Freitag, 22. August 2014 18:42
An: freesurfer@nmr.mgh.harvard.edu
Betreff: Re: [Freesurfer] 3dvolreg.afni error during mc-sess


Hmm, that means that 3dvolreg.afni that comes with FS does not run properly on 
your system. Do you already have a full version of AFNI installed on your 
system?
doug


On 08/22/2014 05:00 AM, Milde, Christopher wrote:
 Dear Freesurfer Experts,

 I'm struggling with running only motion correction.
 After running mktemplate-sess which ran well, the mc-sess terminates 
 with the following error.

 The terminal otput is attached:

 3dvolreg.afni: symbol lookup error: 3dvolreg.afni: undefined symbol: 
 afni_ncerr
 ERROR: 3dvolreg.afni

 Some important comments:
 1.) 3dvolreg.afni is within the bin-folder of Freesurfer
 2.) I use partial-field-of-view EPI
 3.) I run mc-sess und dcm2nii formated DICOM-files (is it a 
 prerequisite to use unpacksdcmdir)?

 Thank you, for your support!!!

 Greets Christopher

 *TERMINAL OUTPUT:*

 mc-sess -s PM_00031 -d $FSF_DIR -per-run  -fstem -outfmt nii.gz

 [christopher@fu20a S1]$ mc-sess -s PM_00923 -d $FSF_DIR -per-run 
 -fstem 20 -outfmt nii.gz
 fmt: Undefinierte Variable.
 [christopher@fu20a S1]$ mc-sess -s PM_00923 -d $FSF_DIR -per-run 
 -fstem 20 Logfile is 
 /home/christopher/Desktop/freesurfer/subjects/S1/log/mc-PM_00923-bold.
 log
 ---
 /home/christopher/Desktop/freesurfer/subjects/S1/PM_00923
 RunList: 001 002 004
   --- ** ---
   --- Motion Correcting Run 001 ---
   --- ** --- sess = PM_00923 Fr 
 22. Aug 09:35:07 CEST 2014
 mc-afni2 --i 001/20.nii.gz --t 001/template.nii.gz --o 
 001/fmcpr.nii.gz --mcdat 001/fmcpr.mcdat 
 /home/christopher/Desktop/freesurfer/subjects/S1/PM_00923/bold
 mri_info --nframes --o /tmp/mriinfo.19767 001/template.nii.gz log file 
 is 001/fmcpr.nii.gz.mclog mcdat file is 001/fmcpr.mcdat tmp dir is 
 001/tmp.mc-afni2.19767 #@#  
 /home/christopher/Desktop/freesurfer/subjects/S1/PM_00923/bold
 mri_convert 001/template.nii.gz 001/tmp.mc-afni2.19767/tempvol.nii.gz
 --nskip 0 --ndrop 0 -odt float
 mri_convert 001/template.nii.gz 001/tmp.mc-afni2.19767/tempvol.nii.gz
 --nskip 0 --ndrop 0 -odt float
 nskip = 0
 ndrop = 0
 $Id: mri_convert.c,v 1.179.2.7 2012/09/05 21:55:16 mreuter Exp $ 
 reading from 001/template.nii.gz...
 TR=2000.00, TE=0.00, TI=0.00, flip angle=0.00 i_ras = (-1, 0, 0) j_ras 
 = (0, -0.218143, 0.975917) k_ras = (0, -0.975917, -0.218143) writing 
 to 001/tmp.mc-afni2.19767/tempvol.nii.gz...
 #@# 
 /home/christopher/Desktop/freesurfer/subjects/S1/PM_00923/bold
 mri_convert 001/20.nii.gz 001/tmp.mc-afni2.19767/invol.nii.gz -odt 
 float mri_convert 001/20.nii.gz 001/tmp.mc-afni2.19767/invol.nii.gz 
 -odt float
 $Id: mri_convert.c,v 1.179.2.7 2012/09/05 21:55:16 mreuter Exp $ 
 reading from 001/20.nii.gz...
 TR=2000.00, TE=0.00, TI=0.00, flip angle=0.00 i_ras = (-1, 0, 0) j_ras 
 = (0, -0.218143, 0.975917) k_ras = (0, -0.975917, -0.218143) writing 
 to 001/tmp.mc-afni2.19767/invol.nii.gz...
 #@# 
 /home/christopher/Desktop/freesurfer/subjects/S1/PM_00923/bold
 3dvolreg.afni -verbose -dfile 001/fmcpr.mcdat -1Dmatrix_save 
 001/fmcpr.mat -base 001/tmp.mc-afni2.19767/tempvol.nii.gz -prefix 
 001/tmp.mc-afni2.19767/outvol.nii.gz 
 001/tmp.mc-afni2.19767/invol.nii.gz
 3dvolreg.afni: symbol lookup error: 3dvolreg.afni: undefined symbol: 
 afni_ncerr
 ERROR: 3dvolreg.afni
 Ungültiger leerer Befehl.





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MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
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[Freesurfer] 3dvolreg.afni error during mc-sess

2014-08-22 Thread Milde, Christopher
Dear Freesurfer Experts,

I'm struggling with running only motion correction.
After running mktemplate-sess which ran well, the mc-sess terminates with the 
following error.

The terminal otput is attached:

3dvolreg.afni: symbol lookup error: 3dvolreg.afni: undefined symbol: afni_ncerr
ERROR: 3dvolreg.afni

Some important comments:
1.) 3dvolreg.afni is within the bin-folder of Freesurfer
2.) I use partial-field-of-view EPI
3.) I run mc-sess und dcm2nii formated DICOM-files (is it a prerequisite to use 
unpacksdcmdir)?

Thank you, for your support!!!

Greets Christopher

TERMINAL OUTPUT:

mc-sess -s PM_00031 -d $FSF_DIR -per-run  -fstem -outfmt nii.gz

[christopher@fu20a S1]$ mc-sess -s PM_00923 -d $FSF_DIR -per-run -fstem 20 
-outfmt nii.gz
fmt: Undefinierte Variable.
[christopher@fu20a S1]$ mc-sess -s PM_00923 -d $FSF_DIR -per-run -fstem 20
Logfile is 
/home/christopher/Desktop/freesurfer/subjects/S1/log/mc-PM_00923-bold.log
---
/home/christopher/Desktop/freesurfer/subjects/S1/PM_00923
RunList: 001 002 004
  --- ** ---
  --- Motion Correcting Run 001 ---
  --- ** ---
sess = PM_00923
Fr 22. Aug 09:35:07 CEST 2014
mc-afni2 --i 001/20.nii.gz --t 001/template.nii.gz --o 001/fmcpr.nii.gz --mcdat 
001/fmcpr.mcdat
/home/christopher/Desktop/freesurfer/subjects/S1/PM_00923/bold
mri_info --nframes --o /tmp/mriinfo.19767 001/template.nii.gz
log file is 001/fmcpr.nii.gz.mclog
mcdat file is 001/fmcpr.mcdat
tmp dir is 001/tmp.mc-afni2.19767
#@# 
/home/christopher/Desktop/freesurfer/subjects/S1/PM_00923/bold
mri_convert 001/template.nii.gz 001/tmp.mc-afni2.19767/tempvol.nii.gz --nskip 0 
--ndrop 0 -odt float
mri_convert 001/template.nii.gz 001/tmp.mc-afni2.19767/tempvol.nii.gz --nskip 0 
--ndrop 0 -odt float
nskip = 0
ndrop = 0
$Id: mri_convert.c,v 1.179.2.7 2012/09/05 21:55:16 mreuter Exp $
reading from 001/template.nii.gz...
TR=2000.00, TE=0.00, TI=0.00, flip angle=0.00
i_ras = (-1, 0, 0)
j_ras = (0, -0.218143, 0.975917)
k_ras = (0, -0.975917, -0.218143)
writing to 001/tmp.mc-afni2.19767/tempvol.nii.gz...
#@# 
/home/christopher/Desktop/freesurfer/subjects/S1/PM_00923/bold
mri_convert 001/20.nii.gz 001/tmp.mc-afni2.19767/invol.nii.gz -odt float
mri_convert 001/20.nii.gz 001/tmp.mc-afni2.19767/invol.nii.gz -odt float
$Id: mri_convert.c,v 1.179.2.7 2012/09/05 21:55:16 mreuter Exp $
reading from 001/20.nii.gz...
TR=2000.00, TE=0.00, TI=0.00, flip angle=0.00
i_ras = (-1, 0, 0)
j_ras = (0, -0.218143, 0.975917)
k_ras = (0, -0.975917, -0.218143)
writing to 001/tmp.mc-afni2.19767/invol.nii.gz...
#@# 
/home/christopher/Desktop/freesurfer/subjects/S1/PM_00923/bold
3dvolreg.afni -verbose -dfile 001/fmcpr.mcdat -1Dmatrix_save 001/fmcpr.mat 
-base 001/tmp.mc-afni2.19767/tempvol.nii.gz -prefix 
001/tmp.mc-afni2.19767/outvol.nii.gz 001/tmp.mc-afni2.19767/invol.nii.gz
3dvolreg.afni: symbol lookup error: 3dvolreg.afni: undefined symbol: afni_ncerr
ERROR: 3dvolreg.afni
Ungültiger leerer Befehl.



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Re: [Freesurfer] mri_surfcluster for FEAT cluster maxima

2014-08-14 Thread Milde, Christopher
Dear Doug,

thanks for your helpful comments according to the reading out fMRI cluster peak 
vertices!

Actually, I'm able now to read out cluster peak vertices (see bottom). I 
applied the mri_surfcluster command for resampled and surface smoothed Feat 
stats on smoothwm surface with projfrac 0.5 (mri_surf2surf -fwhm).

But I'm not sure how to apply Multiple Comparison Correction because I only 
found this option for group statistics (mri_glmfit-sim). For this purpose, I 
have to generate a GLM within Freesurfer.
I use FEAT preprocessed but unsmoothed data and coregistered/resampled it to 
the surfaces. My goal is to read out peak vertices on session/single-subject 
level, preferentially on the smoothwm with -projfrac 0.5.
Is it possible to use the mkanalysis-sess/mkcontrast-sess/selxvavg3-sess 
commands (seemingly it’s just for FSFAST preprocessed data) in combination with 
a Multiple Comparisons Correction at session level? OR Shall I run the 
Preprocessing in FSFAST too?
Hopefully, there is a solution for this delicate problem

Sincerely yours,

Chris

mri_surfcluster --subject PM_00880_inflation --surf smoothwm --hemi lh --in 
PM_00880_inflation/TR.feat/stats/smooth_10.mgz --thmin 2 --thmax inf --sign pos 
--minarea 30 --annot aparc --sum PM_00880_inflation/TR.feat/stats/TR_summary2
thsign = pos, id = 1
version $Id: mri_surfcluster.c,v 1.51.2.3 2012/05/31 22:10:05 greve Exp $
hemi   = lh
srcid  = PM_00880_inflation/TR.feat/stats/smooth_10.mgz
srcsubjid  = PM_00880_inflation
srcsurf= smoothwm
srcframe   = 0
thsign = pos
thmin  = 2
thmax  = inf
fdr= -1
minarea= 30
xfmfile= talairach.xfm
nth = -1
sumfile  = PM_00880_inflation/TR.feat/stats/TR_summary2
subjectsdir= /home/christopher/Desktop/freesurfer/subjects
FixMNI = 1
- XFM matrix (RAS2RAS) ---
/home/christopher/Desktop/freesurfer/subjects/PM_00880_inflation/mri/transforms/talairach.xfm
 1.052   0.044  -0.055   0.749;
-0.027   1.026   0.319  -8.121;
 0.030  -0.345   1.096  -13.593;
 0.000   0.000   0.000   1.000;

Reading source surface 
/home/christopher/Desktop/freesurfer/subjects/PM_00880_inflation/surf/lh.smoothwm
Done reading source surface
Reading annotation 
/home/christopher/Desktop/freesurfer/subjects/PM_00880_inflation/label/lh.aparc.annot
reading colortable from annotation file...
colortable with 36 entries read (originally 
/autofs/space/terrier_001/users/nicks/freesurfer/average/colortable_desikan_killiany.txt)
Computing metric properties
Loading source values
number of voxels in search space = 133455
Done loading source values (nvtxs = 133455)
overall max = 5.55723 at vertex 63001
overall min = -4.84855 at vertex 19315
surface nvertices 133455
surface area 79513.531250
surface area 79513.859375
Adjusting threshold for 1-tailed test.
If the input is not a -log10(p) volume, re-run with --no-adjust.
Searching for Clusters ...
thmin=2.00 (1.698970), thmax=inf (inf), thsignid=1, minarea=30.00
Found 9 clusters
Max cluster size 1315.766113
INFO: fixing MNI talairach coordinates






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[Freesurfer] mri_surfcluster for FEAT cluster maxima

2014-08-12 Thread Milde, Christopher
Dear Freesurfers,

I’m struggling with finding a way of getting a table of the cluster maxima of 
FEAT functional data registered to (reg-feat2anat) and resampled to (feat2surf) 
reconstructed surfaces. I want to extract cluster maxima for single subjects 
but preferentially NOT in fsaverage group space.

The command mri_surfcluster seems to be quite promising for this purpose. 
Specifically the summary file with the VtxMax

But, seemingly I use the wrong input file (-in) for the FEAT functional data 
(Error wrong type for mghRead).
1.) Is it at all possible to read resampled Feat data with mri_surfcluster?
2.) is it a prerequisite to run mri_glmfit as suggested in
https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/FslGroupFeat (I do not 
want to perform analysis in group space)


I'm very thankful for advice

Sincerely yours,

Chris

$ mri_surfcluster --subject PM_02173_inflation --in 
PM_02173_inflation/ML_us.feat/stats/zstat1.mgh --hemi lh --surf smoothwm 
--thmin 2 --thmax inf --sign pos --minarea 15 --annot aparc


thsign = pos, id = 1
version $Id: mri_surfcluster.c,v 1.51.2.3 2012/05/31 22:10:05 greve Exp $
hemi   = lh
srcid  = PM_02173_inflation/ML_us.feat/stats/zstat1.mgh
srcsubjid  = PM_02173_inflation
srcsurf= smoothwm
srcframe   = 0
thsign = pos
thmin  = 2
thmax  = inf
fdr= -1
minarea= 15
xfmfile= talairach.xfm
nth = -1
subjectsdir= /home/christopher/Desktop/freesurfer/subjects
FixMNI = 1
- XFM matrix (RAS2RAS) ---
/home/christopher/Desktop/freesurfer/subjects/PM_02173_inflation/mri/transforms/talairach.xfm
 1.127  -0.010  -0.020   0.954;
 0.005   0.993   0.048  -16.639;
 0.017  -0.052   1.162  -15.969;
 0.000   0.000   0.000   1.000;

Reading source surface 
/home/christopher/Desktop/freesurfer/subjects/PM_02173_inflation/surf/lh.smoothwm
Done reading source surface
Reading annotation 
/home/christopher/Desktop/freesurfer/subjects/PM_02173_inflation/label/lh.aparc.annot
reading colortable from annotation file...
colortable with 36 entries read (originally 
/autofs/space/terrier_001/users/nicks/freesurfer/average/colortable_desikan_killiany.txt)
Computing metric properties
Loading source values
mghRead(PM_02173_inflation/ML_us.feat/stats/zstat1.mgh, -1): could not open file
ERROR: could not read PM_02173_inflation/ML_us.feat/stats/zstat1.mgh as type

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Re: [Freesurfer] smoothing functional data on smoothwm surface

2014-06-18 Thread Milde, Christopher
Dear Doug,

unfortunately, I don't know how to define the source (EPI) and target 
(smoothwm) within the mri_surf2surf command to apply smoothing on the FEAT 
functional data.

My aim is to apply smoothing of the FEAT functional data AFTER being resampled 
to the smoothwm (to avoid deficient smoothing due to attached cortical banks 
given by VBR-approaches)

mri_surf2surf --s PM_02173 --hemi lh --sval ???  --fwhm 10 --trgsurfval smoothwm

is smooth-out a better option?
--smooth-out (to apply smoothing after resampling to the smoothwm)

ps: Might tksurfer be an alternative? Using: tksurfer subject lh smoothwm 
-overlay [FEAT functional] -overlay-reg [...anat2exf.register.dat ] and apply 
smoothing by using Tools-- Surface -- Overlay Smoothing?

Kindly regards,

Christopher

Von: freesurfer-boun...@nmr.mgh.harvard.edu 
[mailto:freesurfer-boun...@nmr.mgh.harvard.edu] Im Auftrag von Douglas Greve
Gesendet: Montag, 16. Juni 2014 17:30
An: freesurfer@nmr.mgh.harvard.edu
Betreff: Re: [Freesurfer] smoothing functional data on smoothwm surface


Use mri_surf2surf with the --fwhm option
doug

On 6/16/14 3:13 PM, Milde, Christopher wrote:
Dear Freesurfers,

I'm interested in smoothing preprocessed (but unsmoothed) functional FEAT data, 
which was coregistered and resampled to the anatomical surface (using: 
reg-feat2anat/feat2surf).

I want to apply smoothing on the functional data preferentially on a surface 
which doesn't suffer from metric distortions (like the inflated OR sphere). I 
thought about using the smoothwm surface.

Questions:
Which command can I use for smoothing the feat functional data on the smoothwm 
AND furthermore, how can I extract the cluster maxima afterwards???

I'm thankful for any helpful comment,

Greetz,

Christopher






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[Freesurfer] smoothing functional data on smoothwm surface

2014-06-16 Thread Milde, Christopher
Dear Freesurfers,

I'm interested in smoothing preprocessed (but unsmoothed) functional FEAT data, 
which was coregistered and resampled to the anatomical surface (using: 
reg-feat2anat/feat2surf).

I want to apply smoothing on the functional data preferentially on a surface 
which doesn't suffer from metric distortions (like the inflated OR sphere). I 
thought about using the smoothwm surface.

Questions:
Which command can I use for smoothing the feat functional data on the smoothwm 
AND furthermore, how can I extract the cluster maxima afterwards???

I'm thankful for any helpful comment,

Greetz,

Christopher


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[Freesurfer] Extract peak voxel (vertex) coordinates from surfaces

2014-05-30 Thread Milde, Christopher
Dear Freesurfers,

I would be interested in figuring out the peak vertex of clusters based on 
coregistered functional FEAT data with the reconstructed anatomical surfaces.

The FEAT preprocessing was run without smoothing and smoothing was applied 
after the feat2surf

Does anyone know how to obtain the peak coordinate (preferentially on smoothwm 
surface) ?  I need exact vertex indices for running mris_pmake

Kindly regards,

Christopher

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[Freesurfer] finding cluster peak vertices

2014-05-23 Thread Milde, Christopher
Dear Freesurfers,

Is there a way to smooth already preprocessed functional images* (FEAT, FSL), 
which I coregistered to the reconstructed surfaces (reg feat2anat), on the 
cortical surface?

Furthermore, I would be interested in finding the cluster peak vertex after 
smoothing the EPI on the reconstructed surface. I know that Hagler et al 2006 
talked about a vertex search method to find the maximally activated vertex on 
the surface.

Kindly regards,

Christopher

*the FEAT preprocessed and 1st level statistics FEATs are not smoothed to avoid 
blurring across attached gyri

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[Freesurfer] distance comparisons across subjects in fsaverage group sphere

2014-05-12 Thread Milde, Christopher
Dear Freesurfers,

In Fischl et al. 1999 it is highlighted, that the topological structure of the 
original surface is preserved in the spherical space and due to the nature of a 
sphere, computations (distance, area) measures are easy to make.

My question now, concerns the comparability of distance measures between 
subjects in the group fsaverage sphere. My aim is to compare distances between 
peak voxels coordinates of two study populations, to figure out if a systematic 
difference exist between the peak voxel distances of the two study populations.

Can I compare the distances between peak voxels (vertices) between different 
subjects based on the fsaverage group sphere? So, is the comparability of 
distances between vertexes of individually spheres preserved in group fsaverage 
space?

Ps: I know that the distances in spherical space are not Euclidian but still 
geodesic


Best wishes and thanks in advance,


Christopher Milde, M.Sc. Biol.
Institute for Cognitive and Clinical Neuroscience
Central Institute of Mental Health Square J 5
68159 Mannheim, Germany


Christopher Milde, M.Sc. Biol.
Institute for Cognitive and Clinical Neuroscience
Central Institute of Mental Health Square J 5
68159 Mannheim, Germany

Phone:  +49-621-1703-6313
E-mail:  christopher.mi...@zi-mannheim.de
Homepage:http://www.zi-mannheim.de/
Office:  Forschungs- und Verwaltungsgebäude, Room 230

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Re: [Freesurfer] distance comparisons across subjects in fsaverage group sphere

2014-05-12 Thread Milde, Christopher
Thanx Bruce,

I will try out your suggestion and let you know. I think I will get a good 
estimate of the degree of metric distortions, because I have a lot of subjects 
tested ;-)

If this will not work, or the distortions are to big, I will make use of the 
Spline Tool in Freeview manually drawing a line within the cortical ribbon 
between the peak voxels, whereby benefitting from the reconstructed surface 
brain with superimposed EPI (with post inflation smoothed EPI data) for visual 
comparison (to benefit from the SBR versus VBR information, to avoid the 
problem of guessing if an activated cluster belongs to Gyrus A or B when the 
Cluster is spread along two attached gyri). Maybe I can also make use of the 
coordinate transormations RAS --sphere

Greetz,

Christopher
 

Von: freesurfer-boun...@nmr.mgh.harvard.edu 
[freesurfer-boun...@nmr.mgh.harvard.edu]quot; im Auftrag von quot;Bruce 
Fischl [fis...@nmr.mgh.harvard.edu]
Gesendet: Montag, 12. Mai 2014 15:46
An: Freesurfer support list
Betreff: Re: [Freesurfer] distance comparisons across subjects in fsaverage 
group sphere

Hi Christopher

the spherical mapping usually has on the order of 17-20% distortion in
distances, and the registration is probably significantly more. I'm not
entirely sure what are trying to do, but you can measure the difference in
great circle length between the sphere and sphere.reg to get an idea of how
much additional distortion is induced by the registration

cheers
Bruce



On Mon, 12 May 2014, Milde, Christopher wrote:


 Dear Freesurfers,



 In Fischl et al. 1999 it is highlighted, that the topological structure of 
 the original
 surface is preserved in the spherical space and due to the nature of a 
 sphere, computations
 (distance, area) measures are easy to make.



 My question now, concerns the comparability of distance measures between 
 subjects in the
 group fsaverage sphere. My aim is to compare distances between peak voxels 
 coordinates of
 two study populations, to figure out if a systematic difference exist between 
 the peak voxel
 distances of the two study populations.



 Can I compare the distances between peak voxels (vertices) between different 
 subjects based
 on the fsaverage group sphere? So, is the comparability of distances between 
 vertexes of
 individually spheres preserved in group fsaverage space?



 Ps: I know that the distances in spherical space are not Euclidian but still 
 geodesic





 Best wishes and thanks in advance,





 Christopher Milde, M.Sc. Biol.

 Institute for Cognitive and Clinical Neuroscience

 Central Institute of Mental Health Square J 5

 68159 Mannheim, Germany





 Christopher Milde, M.Sc. Biol.

 Institute for Cognitive and Clinical Neuroscience

 Central Institute of Mental Health Square J 5

 68159 Mannheim, Germany



 Phone:  +49-621-1703-6313

 E-mail:  christopher.mi...@zi-mannheim.de

 Homepage:http://www.zi-mannheim.de/

 Office:  Forschungs- und Verwaltungsgebäude, Room 230






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[Freesurfer] native or fsaverage spherical space for distance measures?

2014-04-01 Thread Milde, Christopher
Dear Freesurfers,

according to my research and 'playing-around' with Freesurfer tools on 
measuring distances between vertices or peak voxels, I'm still unsure about the 
most adequate way of comparing distances between peak voxels corrected for 
folding patterns.

To my current knowledge, I figured out the following procedures:

Goal: comparing cortical distances between peak voxels between subjects of 
different clinical populations


1.)Manual procedure using Freeview spline tool: using orig.mgz + white and 
pial surfaces + thresh_zstat images (FSL)

è Using Measure tool (spline) to create a smoothed line within the cortical 
ribbon

è Output: absolute cortical distances in [mm]

è Problem: topologically remote but geometrically close by peak voxels (maybe 
avoidable by using the RAS to vertex transformation information of the inflated 
brain)



2.)Automated procedure: using mris_pmake  with start vertex stop vertex 
coordinates derived from the population averaged sphere coordinate systems 
(fsaverage sphere) (functional data mapped into common sphere by either 
feat2surf or mris_preproc)



è Output: only relative distance measures, but the comparability between peak 
voxel distances of different  subjects is ensured (due to distance measures 
within a common spherical coordinate system)*.

è Problem: no absolute measure of distances anymore (but this is actually no 
problem because I'm interested in relative differences in cortical 
reorganization)



- Do you have any suggestions which procedure is preferable??

- *Am I right about the comparability of distance measurements between 
subjects, when using mris_pmake within a common spherical coordinate space??



I appreciate any helpful comment



Sincerely yours,



Christopher

Christopher Milde, M.Sc. Biol.
Institute for Cognitive and Clinical Neuroscience
Central Institute of Mental Health Square J 5
68159 Mannheim, Germany

Phone:  +49-621-1703-6313
E-mail:  christopher.mi...@zi-mannheim.de
Homepage:http://www.zi-mannheim.de/
Office:  Forschungs- und Verwaltungsgebäude, Room 230

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Re: [Freesurfer] combine FEAT data with inflated ANATOMY to measure distances

2014-03-21 Thread Milde, Christopher
Dear Doug,

I'm very thankful for your helpful comments! I will check the feat2surf script 
and apply it to map FSL-data in individual and common space (preconditions: 
existing FEATdir with non-smoothed EPI's and applied reg-feat2anat). I will 
make use of the -projfrac 0.5 to sample in the middle of the cortical ribbon 
(to account for drain vessel effects).

According to the intended distance measures, relative measures between peak 
voxels are also fine. So, maybe mris_pmake is still a good option...

Greets, Chris


Christopher Milde, M.Sc. Biol.
Institute for Cognitive and Clinical Neuroscience 
Central Institute of Mental Health Square J 5
68159 Mannheim, Germany 

Phone:  +49-621-1703-6313
E-mail:  christopher.mi...@zi-mannheim.de
Homepage:http://www.zi-mannheim.de/
Office:  Forschungs- und Verwaltungsgebäude, Room 230



-Ursprüngliche Nachricht-
Von: freesurfer-boun...@nmr.mgh.harvard.edu 
[mailto:freesurfer-boun...@nmr.mgh.harvard.edu] Im Auftrag von Douglas N Greve
Gesendet: Donnerstag, 20. März 2014 16:26
An: freesurfer@nmr.mgh.harvard.edu
Betreff: Re: [Freesurfer] combine FEAT data with inflated ANATOMY to measure 
distances


1) Use the feat2surf script
2) I have not used mris_pmake myself. I'm guessing it will *work* on the sphere 
in that it will return a path, but the distances between vertices have no 
relationship to anatomy. It might fail on a flat map because it is a patch.

doug



On 03/20/2014 10:43 AM, Milde, Christopher wrote:

 Dear Surfers,

 At moment I'm dealing with a huge dataset, preprocessed (with and 
 without smoothing) and statistically analyzed in FSL FEAT.

 I used the reg-feat2anat to project functional EPI on inflated MPRAGE 
 (recon-all).

 Because *I'm interested in measuring Euclidian distances between peak 
 voxels*, I want to project *FEAT EPI-data on cortical flat maps
 (mris_flatten) or spherical surfaces*.

 èIs it possible to project FEAT-data on flat_maps?

 èDoes mris_pmake* works equally fine on different projections of the 
 EPI to ANATOMY (sphere, flat map) to measure peak/vertex distances?

 *https://mail.nmr.mgh.harvard.edu/pipermail//freesurfer/2011-April/017
 866.html 
 https://mail.nmr.mgh.harvard.edu/pipermail/freesurfer/2011-April/0178
 66.html

 I'm a quite Surfer-newby. So sorry for that maybe stupid question.

 Thank you in advance,

 Christopher

 *Christopher Milde, M.Sc. Biol.*

 Institute for Cognitive and Clinical Neuroscience

 Central Institute of Mental Health Square J 5

 68159 Mannheim, Germany

 Phone: +49-621-1703-6313

 E-mail: christopher.mi...@zi-mannheim.de

 Homepage: http://www.zi-mannheim.de/ http://www.zi-mannheim.de/

 Office: Forschungs- und Verwaltungsgebäude, Room 230



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[Freesurfer] combine FEAT data with inflated ANATOMY to measure distances

2014-03-20 Thread Milde, Christopher
Dear Surfers,

At moment I'm dealing with a huge dataset, preprocessed (with and without 
smoothing) and statistically analyzed in FSL FEAT.

I used the reg-feat2anat to project functional EPI on inflated MPRAGE 
(recon-all).

Because I'm interested in measuring Euclidian distances between peak voxels, I 
want to project FEAT EPI-data on cortical flat maps (mris_flatten) or spherical 
surfaces.

è Is it possible to project FEAT-data on flat_maps?

è Does mris_pmake* works equally fine on different projections of the EPI to 
ANATOMY (sphere, flat map) to measure peak/vertex distances?



*https://mail.nmr.mgh.harvard.edu/pipermail//freesurfer/2011-April/017866.htmlhttps://mail.nmr.mgh.harvard.edu/pipermail/freesurfer/2011-April/017866.html


I'm a quite Surfer-newby. So sorry for that maybe stupid question...

Thank you in advance,

Christopher


Christopher Milde, M.Sc. Biol.
Institute for Cognitive and Clinical Neuroscience
Central Institute of Mental Health Square J 5
68159 Mannheim, Germany

Phone:  +49-621-1703-6313
E-mail:  christopher.mi...@zi-mannheim.de
Homepage:http://www.zi-mannheim.de/
Office:  Forschungs- und Verwaltungsgebäude, Room 230

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