I have only a few moments of time, at present. However, I offer a couple of comments on your inquiry.
First, there are a wide variety of enzymes which will act as solvents/penetrants of MANY membrane-type tissues/films. Bromelain
is one (a very effective one) of many. Some enzymes are "narrow spectrum" in effect and some are "wide spectrum". I have no knowledge of the effects of specific enzymes on the effectiveness/enhancement of antibiotics.
Briefly, the most effective liposomal substances are...as a general rule....the smallest in particle size. Ultrasonic
devices and HIGH PRESSURE DIFFRACTION DEVICES are, at present, the most effective for accomplishing this. Conventional air compressors could serve, quite adequately, in a large number of applications. The proviso being that one is aware that geometry
of the discharge assembly is of great importance (small particles are vital to non-injurious success).
We have utilized 90% colloidal silver X 10% DMSO SOLUTIONS to very powerful effect in addressing serious pulmonary insults in equines (all ages). We have not used enzymes in direct-address situations involving horses. Primarily, because nothing we have ever evaluated has approached the ability of DMSO as a mucous-barrier penetrating agent. Coarse-particled
gases (liquid mixtures) pose a potential threat for enabling pneumonia-type insults.
Liposomal encapsulation does, indeed, offer some profound advantages.....especially when utilized through proper
supporting equipment. However, I would counsel that "fiddling/experimenting" with pulmonary challenges among horses, by inexperienced persons (even professionals), is a very DANGEROUS endeavor. The least threatening/effective protocols we have ever utilized involved oxygen-driven fluids which were micro-sized and furnished via systems of the re-breather type.
I must go now. I hope these comments are of value to you.
Sincerely, Brooks Bradley.








---------[ Received Mail Content ]----------

Subject : Re: CS>one for brooks

Date : Tue, 19 Jan 2010 12:58:16 -0600

From : Dan Nave <bhangcha...@gmail.com>

To : silver-list@eskimo.com



Oral bromelain was reported to be very effective in potentiating

antibiotics. I think this is due to it's action in

penetrating/dissolving biofilms, or some similar action.



Dan



On Tue, Jan 19, 2010 at 9:47 AM, polo wrote:

> Hopefully Brooks will have time to consider and comment on this.

>

>     I have long been interested in protocols that will efficiently attack

> biofilm infections. It seems that inhaled (nebulized) liposomal

> medications are very effective in penetrating very difficult to treat lung

> biofilms. Some recent studies have suggested that liposomal antibiotics are

> superb treatments. Here is one:

>

> http://jac.oxfordjournals.org/cgi/content/full/61/4/859

>

>

>     The above study used a compressor type of nebulizer (nebulizer PARI LC

> Star).   Anyway, I would like to try liposomal colloidal silver in a

> nebulizer for biofilm lung infections, particularly in racehorses. Normally

> we use ultrasonic nebulizers as opposed to the older compressor type

> nebulizers as was used in the above study. Ultrasound nebulizers vaporize

> the medication into super small droplets that can be pushed into the lung

> via an air jet. The older compressor type uses a small air compressor to

> vaporize the inhaled medication producing larger medication particles to be

> breathed in. Naturally, the ultrasound nebulizer technology produces small

> droplet size which is more conducive to lung inhalation efficacy.

>

>     What I would like to know, do you see any problems with producing

> colloidal silver liposomes using your home made protocol and (2) would an

> ultrasonic nebulizer be detrimental to the liposomal structure? Would an

> older compressor type nebulizer as used in the study be better in putting

> liposomes into solution for inhalation purposes or would the newer utrasonic

> nebulizers not over-whelming affect liposomal structure upon vaporzation or

> might it even be beneficial?

>

>     As a side note, I want to add that heavy metals seem particularly

> effective against biofilms of which I would venture a guess that colloidal

> silver would be a superb medication, if one could only get it to be absorbed

> by the biofilm. Liposomal technology may be the key!

>

> doug





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