Sol, 
Thanks for note.  Her  paw/skin color on legs didn't come back right away, but 
considering I wouldn't call it long. Maybe I am first to experience this, but 
just my observation. Regardless I am glad I tried it, no regrets at all and now 
we can working our way up the ladder to see her belly and some of her skin get 
lighter in color.  It could have been a combo of things too as I believe she 
was on drugs still at this point.  Who knows, but she appears on the mend and 
grateful to be here w/the group, learning so much and opportunity to readjust 
her diet through this wisdom or my choices of what my next steps are.  

If I had a specific answer why it happened I would gladly shed light on her 
skin/paw appearance...w/silverish look I could only associate it with the CS, 
but maybe it was compounded by the steroids/antibiotics she was on and together 
it culminated to this.   I wish I knew.

Thanks again for sharing your perspective Sol.  I  think I've exhausted my 
fingers to write more on this here.  I'm going to let this subject rest for a 
while.....right now I am working on a few large bumps on her head, her red skin 
in certain areas and her red belly.  In a few days she'll be back at the new 
vet and see what is our next step.

Yup I am new here, not an expert by any means, but learning and growing out of 
curiosity which is exciting to me.

Thanks Sol.

carolg




________________________________
From: sol <sol...@sweetwaterhsa.com>
To: silver-list@eskimo.com
Sent: Sat, March 6, 2010 9:13:51 PM
Subject: Re: CS>color change dog's paws and legs, would like opinions  on how   
CS could cause it?

At 08:49 PM 3/6/2010, you wrote:
> Sol,
> 
> Perhaps my message didn't come through with the a response to your question 
> of my dogs color of fur or skin color noticeable changes or it was missed.  
> So here's the answer:
> 
> skin color on paws and legs only changed--not fur.

Thanks, that was not clear to me at all, so I am happy to have you clarify it 
in terms I can understand.


> Believe it or not, this is my story and our eyes including the VET seeing it 
> too which I just remember asking him about.
> 
> I don't exactly recall how many days or weeks, at this point as I didn't 
> chart it, but my posts you may be able to track for more exact details before 
> it became noticeable.  It may have just happened....I don't have scientific 
> proof to back up my sayings other than my eyes and others who saw dog.

My point is that I have never ever seen such a skin color change posted about 
in any other animal, and though it may be inaccurate to generalize from human 
cases of argryia to an animal, but in a human argryia (so far as I know to 
date) does not develop in one month, nor does it reverse in weeks after 
stopping CS. You may have followed the thread on those here who have argryia 
from YEARS of high dose CS. I have blue moons, that appeared after about 2.5 
years of very high dose CS daily. It is now about 5 years since I acquired the 
color in my nails, and during those 5 years I have not taken CS daily and not 
ever in constant high doses, and the color has not left, and hasn't even faded 
much.
I just don't see how CS could cause what you saw in your dog (I do not say you 
didn't see it, obviously you did) and I have seen NO similar reports at all in 
an animal or a human. CS takes a long time to build up to causing skin color 
changes, and a long time to reverse the color change if it can EVER be 
reversed, which is debatable, and may be different for different individuals.
I hope my question may bring up some ideas and different input. Maybe someone 
else has seen something similar in an animal and just never posted about it. If 
so, it will be interesting to see ideas on how CS could work so very 
differently in an animal than in humans in this one instance, since in all 
other instances I am aware of, mechanisms of action of CS are virtually the 
same in all mammals, and even in birds.

It is human and normal to see something happen and attribute it to the new and 
unfamiliar thing that has been added to a treatment regimen. That doesn't mean 
such a conclusion is correct. To be perfectly honest, if you were not new to 
CS, and had had years of experience with it, I believe you might have looked 
for another cause. It may yet turn out you are right and it was the CS, but 
someone needs to give me a good rational mechanism for how CS could have done 
it and it reversed so quickly, given what we think we know about how CS works, 
and how it accumulates in body tissues to date. Without that, I cannot believe 
you have the right cause.
sol