Jeanie,
Thanks for your interest and suggestion. We have gone over all his other meds
with doctors and nothing should affect the liver. He doesn't take any OVC pain
meds, or any pain meds. And he does not drink alcohol. The primary doctor
says that the drug information for bosulif says it can cause liver problems,
but Dr Talpaz is less certain of that and he is the specialist. He says he is
watching it closely and I guess we will just trust him. Wayne is getting blood
tests every other week locally and they are sent to Dr Talpaz. The liver
enzyme levels seem to have stabilized, although they are elevated. As you say,
faith and pills. One of Wayne's mottos is "Better living through chemistry".
LOL I think that used to be part of a TV ad for a large chemical company,
maybe Du Pont or Monsanto.
Joyce in IL
On Jul 23, 2015, at 11:32 AM, 'Icandoallttc' via CMLHope wrote:
> Be careful with his diet. Ovc pain pills hurt the liver as well as other
> drugs we take. Ask your pharmacy if any other drugs he take are hurting his
> liver. It's hard but maybe they can figure out something.
> Good luck.
>
> My Motto: Faith and Pills
> Jeanie 🐟🐟18,s
> Dx 1/2004. CML Leukemia
> Started Gleevec 2/2004
> Started Tasigna 9/2009
> Started Sprycel 11/2009
> Started Ponatinib January 2015
> Dr Balducci Moffitt Cancer Center
>
> On Jul 22, 2015, at 2:01 PM, lrc lrc <kneesrb...@gmail.com> wrote:
>
>> Joyce does he drink alcohol?
>>
>> On Jul 22, 2015 1:43 PM, "margood18 via CMLHope" <cmlhope@googlegroups.com>
>> wrote:
>> Joyce, so glad to hear that your husband's PCR is lower and I hope that his
>> liver function will steady. Best wishes to both of you.
>>
>> Marcie
>>
>>
>> -----Original Message-----
>> From: Joyce Mesnarich <joy...@htc.net>
>> To: cmlhope <cmlhope@googlegroups.com>
>> Sent: Wed, Jul 22, 2015 12:16 pm
>> Subject: [CMLHope] New results
>>
>> Hello everyone. I have not had time to contribute for awhile. But I must
>> let
>> you all know the results of my husband's PCR at his last visit to Dr Talpaz.
>> He
>> was taken off Sprycel due to pleural effusion and we were hoping his
>> undetectable would hold....but it did not. He was subsequently put on
>> bosulif
>> and not showing much improvement after 3 months. So his dosage was changed
>> from
>> 100 mg to 200 mg. And now, after 3 more months, his PCR went from 8.7 to
>> 0.127!! Hopefully in another 3 months he will once again reach
>> undetectable.
>>
>> The downside of his test results is that the liver function
>> tests have increased a lot. The doctor will not really say that bosulif is
>> to
>> blame, but nothing else has changed. Has anyone of you CML warriors had any
>> problems with the liver while on TKI's? Was there any treatment to help the
>> liver?
>>
>> God bless you all.
>>
>> Joyce in IL
>>
>>
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