Hi Tracey, The Recomb Rates track on hg19 might be helpful to you (it's in th e Mapping and Sequencing Tracks section) - it displays the recombination rates across the genome. You will have to determine what counts as a hot spot. But you can use the table browser to filter this track to only display recombination rates that are over a given threshold. To do this:
1. Go to the Table Browser: http://genome.ucsc.edu/cgi-bin/hgTables 2. Select hg19 and the Recomb Rates track (click the 'describe table schema' button to become familiar with the table/data) 3. Make sure region is set to genome 4. Click the create button next to "filter" 5. Filter on one of more fields (e.g., decodeAvg >= 2.0) - and click submit 6. set output format: custom track, and 'get output' 7. Name your custom track and 'get output in genome browser' Alternately, you can download the raw data just be selecting output format 'all fields from selected table' and giving it a file name. Please let us know if you have any additional questions: [email protected] - Greg Roe UCSC Genome Bioinformatics Group On 10/31/11 12:17 PM, [email protected] wrote: > Hi, > > I am doing my Masters Thesis on recombination hotspots and their influence > on disease genes. I need to get hold of the hotspot co-ordinates for > humans but am unable to find the details in HapMap or anywhere else. Can > you let me know where to find this info please. > > Thanking you in advance. > > Kind regards > > Tracey > South African National Bioinformatics Institute > Cape Town > South Africa > > _______________________________________________ > Genome maillist - [email protected] > https://lists.soe.ucsc.edu/mailman/listinfo/genome _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
