[ccp4bb] Postdoc positions at Francis Crick Institute/Imperial College London

[Zhang, Xiaodong]

Postdoc positions are available in my group 
(www.imperial.ac.uk/people/xiaodong.zhang).
 We are currently seconded to the Francis Crick Institute 
(www.crick.ac.uk/research/labs/xiaodong.zhang),
 which is located a short tube-ride away. The successful candidate will join a 
multi-disciplinary team of international researchers investigating the 
structures and mechanisms of key complexes in homologous recombination and DNA 
repair. The post will mainly be located at the Francis Crick Institute but will 
also be able to work at Imperial College London, South Kensington campus. We 
employ a combination of biochemistry, biophysics, X-ray crystallography and 
cryo-electron microscopy, utilizing our state-of-the-art facilities at the 
Francis Crick Institute and Imperial College London. We are looking for 
candidates with a PhD in biochemistry, biophysics, structural biology or 
relevant discipline and have a demonstrated track record in conducting high 
quality original research. This post is funded by a Wellcome Trust Discovery 
Award and will be initially for 3 years.

Our preferred method of application is online via our website 
http://www3.imperial.ac.uk/employment (please select “Job Search” then MED04554 
into “Keywords”).  Please complete and upload an application form as directed, 
attaching a curriculum vitae, a cover letter and the name and contact details 
of two referees.  For informal enquiries please contact me directly. 
xiaodong.zh...@imperial.ac.uk or 
xiaodong.zh...@crick.ac.uk

Application deadline: June 16th 2024.

Professor Xiaodong Zhang FRS
Imperial College London
Sir Alexander Fleming Building, South Kensington, London, SW7 2AZ,
www.imperial.ac.uk/people/xiaodong.zhang
&
The Francis Crick Institute
1 Midland Road, London NW1 1AT
https://www.crick.ac.uk/research/labs/xiaodong-zhang




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions in anti-bacteriophage defense system cryo-EM, cryo-ET and protein design

[Nicholas M I Taylor]

Dear all,


We have 3 postdoctoral positions available in my group at the Novo Nordisk 
Foundation Center for Protein Research, University of Copenhagen. We aim to 
recruit scientists with extensive experience in one or more of the techniques 
of interest to help pioneer and establish this new research field. The 
positions are for 2 years in the first instance and can be renewed for up to 4 
years in total, providing a unique long-term opportunity to work on an exciting 
project in a well-equipped and supportive environment.

Background
Bacteria are under constant attack by bacteriophages, and have evolved 
intricate systems to tackle this constant threat (Doron et al, Science, 2018). 
We have a special focus on anti-bacteriophage defense at the bacterial cell 
envelope/membrane, for which we recently received a large Hallas Møller 
Ascending Investigator grant from the Novo Nordisk Foundation. We have been 
actively working on anti-bacteriophage defense in the past years with our first 
preprint now online (Hu et al., 
https://www.biorxiv.org/content/10.1101/2023.12.18.572097v1).

We will investigate defense systems using three approaches: single particle 
cryo-EM, cryo-electron tomography, and protein bioinformatics/design. Together 
with expert collaborators in phage biology, engineering and light microscopy, 
we aim to unravel fundamentally novel mechanisms in anti-bacteriophage defense 
and biology.

We are looking for three motivated postdocs with experience in one of the three 
approaches to help tackle this exciting challenge.

Position 1
The postdoc will be involved in the expression and purification of components 
of anti-bacteriophage defense systems interacting with the bacterial cell 
membrane. Using single particle cryo-electron microscopy, the postdoc will 
investigate the structure of these systems in different states.

Position 2
The postdoc will study anti-bacteriophage defense systems interacting with the 
bacterial cell membrane using cryo-electron tomography. They will investigate 
how the defense systems are able to ward of bacteriophage infections.

Position 3
The postdoc will investigate anti-bacteriophage defense systems as well as 
phage-encoded inhibitors for these defense systems from a computational point 
of view. In particular, they will use structure prediction to predict novel 
defense systems and protein design to design new defense systems.

 More info and apply here (deadline : January 8 2024, 23.59pm CET):

https://employment.ku.dk/faculty/?show=160758

If you have any questions about the positions, please contact: 
nicholas.tay...@cpr.ku.dk.
Best wishes,

Nicholas

--


Nicholas M. I. Taylor, PhD
Associate Professor

University of Copenhagen
Faculty of Health and Medical Sciences
Novo Nordisk Foundation Center for Protein Research
Blegdamsvej 3B, Office 6.1.14
2200 Copenhagen N
Denmark

nicholas.tay...@cpr.ku.dk
http://www.cpr.ku.dk

[signature_2597359511] [signature_294642431] 



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions available

[Alexandra Deaconescu]

POSTDOCTORAL POSITIONS

at Brown University, USA

 

The Deaconescu Lab at Brown University has two openings for postdoctoral 
researchers. The laboratory's interest is the interplay between DNA repair, 
transcription and other cellular processes ensuring microbial adaptation to 
stressful environments. We deploy a combination of biochemical, biophysical and 
structural techniques. (e.g. X-ray crystallography, small-angle X-ray 
scattering, transmission electron microscopy). For examples of work, please see 
Brugger et al, Nature Communications (2021), Dorich et al., Genes and 
Development (2019), Le et al. Cell (2018), Vemu et al., Science (2018), Kutter 
et al. JMB (2016), Szyk et al, Cell (2014). Positions are partially or 
completely funded from NIH grants.

 

 The first position is focused on protein purification, 
characterization and structure determination by X-ray crystallography. Previous 
experience with biophysical methods (ITC, MST, fluorescence) and enzymatic 
assays a plus.

 

 The second position will be focused on cryo-EM.  A successful 
candidate should be familiar with specimen preparation, data collection as well 
as the processing of images acquired using electron cryo-microscopy. We have 
our own Vitrobot for specimen vitrification and access to state-of-the art 
electron microscopes at Stanford/SLAC (remote data collection is possible) as 
well as a computing cluster. If needed further training in EM can be provided.

 

The candidates should also have the following qualifications: a Ph.D. in the 
field of structural biology or related field; an established track-record of 
publications in peer-reviewed journals.  Must be highly motivated and work 
independently as well as in a team. Excellent spoken and written English are 
required. New Ph.D. graduates are encouraged to apply.  The lab has its own 
Vitrobot, multiple protein purification platforms and a crystallization robot 
etc. Access to EM facilities also available.

 

 Interested candidates should send a CV, one page research experience 
summary and contact information for three references to 
alexandra_deacone...@brown.edu . Salary 
and starting date are negotiable.   Please write Postdoctoral Candidate in the 
e-mail subject header.   Brown University, an Ivy League school, is located 
less than one hour away by train from Boston.   Lab webpage: 
https://deaconesculab.com


-- 
Alexandra Deaconescu, B.E., Ph.D.
Assistant Professor
Brown University

Office: (401) 863-3215
Wet Lab: (401) 863-6729
Computational Lab: (401) 863-7031

For Mail:
Laboratories of Molecular Medicine
70 Ship St. GE-4
Providence, RI 02903

For Courier:
Laboratories of Molecular Medicine
Brown University
70 Ship St., Chestnut St. Loading Dock
Providence, RI 02903

Website: www.deaconesculab.com

Admin
Ms. Tammy Glass
Email: tammy_glass[at]brown.edu
Mailing Address:
Box G-E, Brown University,
Providence, RI 02912-G
Telephone: 401-863-7446

Confidentiality Notice:
This e-mail message, including any attachments, is for the sole use of the 
intended recipient(s) and may contain confidential, proprietary and privileged 
information. Any unauthorized review, use, disclosure or distribution is 
prohibited. If you are not the intended recipient, please contact the sender 
immediately and destroy or permanently delete all copies of the original 
message.








To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/


smime.p7s
Description: S/MIME cryptographic signature

[ccp4bb] PostDoc Positions in FIB-SEM/cryo-ET in Dortmund

[Stefan Raunser]

Dear colleagues!

I would like to draw your attention to the following job opportunities. 
Deadline April 7!

Best,
Stefan
 
PostDoc Positions (m/f/d) in Electron Cryo-Tomography (cryo-ET)

There are exciting immediate Postdoctoral positions in the lab of Stefan 
Raunser in the Department of Structural Biochemistry at the Max Planck 
Institute for Molecular Physiology in Dortmund, Germany. This is a unique 
opportunity to become a part of a world-renowned research institute with a 
diverse faculty with backgrounds in chemistry, biology and physics, and to 
perform interdisciplinary science in a lively and supportive environment!

We seek highly motivated, self-driven and creative thinkers who are prepared to 
take risks in defining and addressing important scientific problems, and who 
use quantitative experimental, computational and/or technical approaches in 
their work. The positions are available immediately in the Department of 
Structural Biochemistry (Director: Stefan Raunser) and are initially limited to 
3 years.

Summary:

Research projects in the Raunser lab focus on important biological questions 
concerning the structural organization of muscles, cytoskeletal proteins and 
bacterial toxin complexes. Our ultimate goal is to understand the mechanisms 
and structure-function relationship underlying these processes in health and 
disease in molecular detail. To this end, we employ single particle electron 
cryo-microscopy (cryo-EM), cryogenic focused ion beam milling (cryo-FIB), 
electron cryo-tomography (cryo-ET), X-ray crystallography, biochemical and 
biophysical methods and cell biology.

There are several projects available in our lab for talented and outstanding 
young researchers who are eager to apply cryo-FIB and cryo-ET to look deeper 
into cells and tissues in order to visualize and understand cellular components 
that have never been seen before.

Requirements:

Ideal candidates should hold an excellent PhD in structural biology, 
biophysics, physics or in an equivalent area with previous experience in single 
particle cryo-EM or cryo-ET.

Strong written and oral communication skills in English are required. 

Why join us?

Being a part of the community at the Max Planck Institute is more than just a 
job. Our dynamic research environment, distinct culture, and diverse community 
foster collaboration and excellence in every corner of science. We offer an 
extensive range of benefits and resources such as:

•   access to state-of-the-art research facilities

•   opportunities to collaborate on cutting-edge research

•   an international and exciting working atmosphere

•   an integrated training program that includes lectures, advanced 
scientific workshops, complementary skill courses and opportunities for career 
development

•   a mentoring program to guide and promote young scientists

Salary:

Payment depends on personal conditions and qualification according to the 
directive of the TVöD. Social benefits correspond to those of the public 
service.

How to Apply:

Applicants should submit a CV, a motivation letter outlining research 
experiences and interests and two reference letters by April 7th, 2023 to 
Stefan Raunser at raunser-jobsea...@mpi-dortmund.mpg.de 

 
Additional Information:

The Max Planck Society (Max Planck Gesellschaft – MPG) is committed to 
increasing the number of individuals with disabilities in its workforce and 
therefore encourages applications from such qualified individuals. The MPG 
seeks to increase the number of women in those areas where they are 
underrepresented and therefore explicitly encourages women to apply. 
Furthermore, the MPG strives to foster an inclusive culture and diversity 
within its workforce. Therefore, all qualified applicants are encouraged to 
apply and will receive consideration for employment without regard to race, 
religion, color, national origin, age, sex, sexual orientation, disability 
status, or any other characteristic protected by applicable law.


---
Prof. Dr. Stefan Raunser | Director | Dep. Structural Biochemistry | Max Planck 
Institute of Molecular Physiology | Otto-Hahn-Straße 11, 44227 Dortmund, 
Germany | +49 231 133 2300

___
3dem mailing list
3...@ncmir.ucsd.edu 
https://mail.ncmir.ucsd.edu/mailman/listinfo/3dem 




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/


smime.p7s
Description: S/MIME cryptographic signature

[ccp4bb] Postdoc positions in cryo-EM development at the MRC Laboratory of Molecular Biology, Cambridge UK

[Jan Löwe]

*Postdoctoral positions available in cryo-EM methods development at the 
MRC Laboratory of Molecular Biology, Cambridge UK, in the groups of 
Chris Russo and Jan Löwe*


We have one position each available, funded for two years as part of the 
LMB’s Blue Sky collaboration with AstraZeneca. The project, in 
collaboration with Kasim Sader at AZ aims to develop novel methods to 
overcome problems with sample denaturation and preferred orientation 
during vitrification of thin aqueous films. Ideas involve outrunning the 
processes involved and modifying the air-water interfaces. The ultimate 
goal is to make cryo-EM sample preparation a much more universal (and 
enjoyable) process.


Cryo-EM experience will be beneficial and a strong desire to engage 
deeply in technical developments is a must. The LMB and AZ provide 
everything required, including a highly collaborative and friendly 
environment, as well as one of the world’s best institutional cryo-EM 
setups, including state-of-the-art machine and electronics workshops, a 
clean room dedicated to grid fabrication, and soon four Titan Krios 
microscopes.


More details and on how to apply are here:

https://www.nature.com/naturecareers/job/12796284/postdoctoral-scientist-structural-studies-dr-jan-loewe-lmb-2097/

https://www.nature.com/naturecareers/job/12796280/postdoctoral-scientist-structural-studies-dr-chris-russo-lmb-2095/

Chris, Kasim and Jan

Jan Löwe
MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK
Email: j...@mrc-lmb.cam.ac.uk
Phone +44 1223 26 7644
Website: http://www2.mrc-lmb.cam.ac.uk/groups/jyl

Christopher J Russo

MRC Laboratory of Molecular Biology 
Cambridge, CB2 0QH, UK
Email: cru...@mrc-lmb.cam.ac.uk

Phone +44 1223 26 7535
Website http://www.mrc-lmb.cam.ac.uk/crusso/




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions in Hamburg – development and validation of sample delivery/preparation for structural-biology experiments

[Arwen Pearson]

Posted on behalf of Jochen Küpper.

—

Dear Colleagues,

My group has multiple openings to work on a novel approach for sample 
preparation in high-resolution cryo-electron microscopy for structural biology. 
This project is in collaboration with partners at the Center for Structural 
Systems Biology (CSSB) in Hamburg and from the cryo-EM industry. Thank you in 
advance for bringing these openings to the attention of possible candidates.

Based on our extensive experience in sample delivery for single-particle 
imaging at XFELs, we developed a novel approach for sample preparation and 
delivery that promises to resolve several of the limitations of current 
sample-preparation methodology. This project is moving toward technological 
validation and we are extending our team to validate and improve the 
methodology and its application in high-resolution structural biology and 
biomedicine.

We are mainly looking for highly motivated research associates at the 
postdoctoral level that are great team players and have extensive experience in 
several of the following fields: aerosol physics and fluid dynamics, cryo-EM 
imaging, biosample handling, biophysics, vacuum operation, cryogenics, laser 
physics, light or particle detectors.
We provide a strong and closely collaborating project team with members from my 
CMI-COMOTION team at DESY and the Marlovits group at CSSB that is in close and 
constructive contact with the advanced technology team of an industrial 
manufacturer.

Please send your application as a single PDF file containing
  • A brief letter of motivation (max. 1 page)
  • Your curriculum vitae
  • A list of 3–5 most important publications and your OrcID
  • The names and contact information of 2-3 persons who can serve as references
Please address your email tooffice.kuep...@cfel.de.

Thank you for your attention,
with my best wishes,
Jochen
-- CFEL Controlled Molecule Imaging Group — 
https://www.controlled-molecule-imaging.org Prof. Dr. Jochen Küpper 
Center for Free-Electron Laser Science (CFEL) Department of Physics & 
Department of Chemistry & Center for Ultrafast Imaging (CUI) Deutsches 
Elektronen-Synchrotron DESY Universität Hamburg Notkestrasse 85 Luruper 
Chaussee 149 22607 Hamburg, Germany 22761 Hamburg, Germany assistant: 
+49-40-8998-6457 phone: +49-40-8998-6330 fax: +49-40-8994-6330 mobile: 
+49-40-899896330 https://www.controlled-molecule-imaging.org/careers 
https://www.molecular-physics.org/news/seminar DPG Division of Molecular 
Physics – https://www.dpg-physik.de/vereinigungen/fachlich/samop/fvmo




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions in Hao Wu lab, Boston

[Hao Wu]

Dear Colleagues,

The Hao Wu lab at Boston Children’s Hospital and Harvard Medical School in 
Boston, MA (https://www.wulab.tch.harvard.edu/) has openings for postdoctoral 
positions to study structures and functions of supramolecular complexes, 
especially those in the inflammasome pathway, using a combination of cryo-EM, 
cryo-ET, cellular imaging and other biochemical, biophysical and cell 
biological techniques. These positions are available immediately as many lab 
members recently moved on to independent academic and industry jobs.

Candidates must have a Ph.D. in Structural Biology, Molecular Biology, 
Biochemistry, or related fields. Preference will be given to candidates with an 
excellent track record from their graduate studies. Good communication and 
organizational skills, and the ability to work independently as well as 
collaboratively are important for these positions.

Salary will be commensurate with the candidate's experience, and will be based 
on the new Harvard Medical School postdoctoral stipend scale that is 
significantly higher than the NIH scale. For those starting their first year of 
postdoctoral training, the scale is 60,000 for fiscal year 2023 and 65,000 for 
fiscal year 2024.

Harvard Medical School has an excellent high resolution cryo-EM facility, 
https://cryoem.hms.harvard.edu/.

Interested candidates should send a short cover letter, CV and contact 
information for three references to 
wu_...@childrens.harvard.edu. Candidates 
will be evaluated on a rolling basis until the positions are filled.
Boston Children’s Hospital and Harvard Medical School promote equity, 
diversity, inclusion and belonging, and are equal opportunity employers.







To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions

[Quyen Hoang]

Hi All,

My group has a couple of Postdoc positions available immediately to study the 
structures and functions of proteins associated with neurodegenerative diseases.
The projects utilize cryo-EM and X-ray crystallography along with a battery of 
other biophysical and biochemical methods.
As such, they might be good opportunities for crystallographers looking to 
learn cryo-EM or microscopists wishing to learn X-ray crystallography (however, 
experiences with these methods are not necessary to apply).
These positions are supported by a new 5-year NIH grant.

Please email me directly (qqho...@iu.edu) if you are interested in learning 
more about these positions.

Cheers,
Quyen

___
Quyen Hoang, PhD
Associate Professor of Biochemistry and Molecular Biology
Director of IUSM Center for Electron Microscopy (iCEM)
Adjunct Associate Professor of Neurology
Primary Investigator of the Stark Neuroscience Research Institute
Indiana University School of Medicine
635 Barnhill Drive, MS0013C
Indianapolis, IN, 46202
(317)274-4371
https://qqhoang.pages.iu.edu



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions at NNF Center for Protein Research, Copenhagen (Taylor Group)

[Nicholas M I Taylor]

Dear all,

I would like to point out we are looking for motivated candidates for two 
exciting postdoctoral positions in our group.

The first one combines protein design and cryo-EM of molecular machines:
https://employment.ku.dk/faculty/?show=156130 (Deadline May 4)

The second position involves functional (deep mutational scanning) and cryo-EM 
of membrane transporters:
https://employment.ku.dk/faculty/?show=156126 (Deadline: May 3)

Please contact me for more details.

Best wishes,

Nicholas


Nicholas M. I. Taylor, PhD
Associate Professor

University of Copenhagen
Faculty of Health and Medical Sciences
Novo Nordisk Foundation Center for Protein Research
Blegdamsvej 3B, building 6.1
2200 Copenhagen N
Denmark

nicholas.tay...@cpr.ku.dk
http://www.cpr.ku.dk

[signature_4114344854] [signature_3260171222] 






To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions in the Plevka lab @ CEITEC, Czech Republic

[Pavel Plevka]

Dear colleagues,

I am seeking 2-3 postdoctoral fellows to join Pavel Plevka's lab of Structural 
Virology at CEITEC. These positions will be part of our ERC-funded project to 
characterize phage invasion of bacterial biofilm or to study replication of 
enteroviruses in situ. The positions are fully funded for up to five years. I 
am looking for colleagues with experience in structural and molecular biology. 
For more information, please see: 

https://www.ceitec.eu/post-doc-positions-in-structural-virology-group-of-pavel-plevka/j367

With best regards.
Pavel





Pavel Plevka
Laboratory of Structural Virology
CEITEC, Masaryk University
Kamenice 5 / A35
Brno, 625 00, Czech Republic
Phone: +420 549 49 7756
###



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions at Cornell in New Approaches to X-ray and Electron-Based Studies of Biomolecular Structure and Function

[Robert Thorne]

*Postdoctoral Associate Positions*

*New Approaches to X-ray and Electron-Based Studies of Biomolecular
Structure and Function*

*Cornell University*

*Ithaca, NY, USA*

Applications are invited for postdoctoral positions in development and
application of instrumentation and methods for time-resolved
crystallography, time-resolved cryo-EM, serial crystallography, and
small-angle X-ray scattering of biomolecular systems. This project is under
the supervision of Physics Prof. Robert Thorne (who is the founder of
MiTeGen, LLC).  Examples of the kind of work involved are described in
IUCrJ 8, 784-792 (2021), IUCrJ 8, 867-877 (2021), Acta Cryst. D 7, 628-644
(2021), and Biophys. J. 104, 227-236 (2013). Candidates should be
comfortable designing, building, and troubleshooting experimental
apparatus, and preferably should have some experience in synchrotron-based
X-ray science or in electron microscopy.  Candidates will gain exposure to
a variety of cutting-edge methods for biostructural science and to the
fundamental physical ideas underlying these methods, providing a strong
basis for a variety of subsequent careers.

Applicants may have a Ph.D. in physics, biophysics, applied physics,
chemistry, materials science, chemical engineering, biomedical engineering,
mechanical engineering, molecular biology or related fields. Relevant
skills include CAD design, microfabrication, machining/3D printing,
apparatus construction, interfacing and testing, optical system design and
assembly, robotics, and programming for data collection and experimental
control. Additional relevant skills that we can provide training in include
protein preparation and crystallization, synchrotron-based X-ray data
collection, cryo-EM data collection, and biomolecular structural analysis
and modeling.

M.S. level candidates with suitable qualifications are welcome to apply for
a related position.

Cornell University has outstanding facilities to support this work,
including the Cornell Nanofabrication Facility (https://www.cnf.cornell.edu/),
the Cornell High-Energy Synchrotron Source (https://www.chess.cornell.edu/),
an electron microscopy facility (
https://www.ccmr.cornell.edu/category/user-instruments/electron-and-optical-microscopy/),
and a well-equipped user  machine shop (
https://www.lassp.cornell.edu/facilities/machine-shop). All these
facilities are staffed by professionals who can provide training and
support.

The successful candidate(s) will refine and acquire a large experimental
skill set, equipping them to tackle challenging problems in biological
science/technology and engineering.

Start dates are flexible and can be as early as April 2022.

Application materials can be submitted to r...@cornell.edu with the
subject  line "Postdoc application".   Complete applications will include a
brief cover letter, a CV, and a  summary of research experience and
interests. Please include a list of your specific experimental and
computational skills.  Recommendation letters will be requested after
application screening.

Cornell University is located in beautiful Ithaca, New York, surrounded by
gorges and waterfalls and the Finger Lakes wine growing region.

Diversity and Inclusion are a part of Cornell University’s heritage. The
College of Arts and Sciences at Cornell embraces diversity and seeks
candidates who will create a climate that attracts students and faculty of
all races, nationalities, and genders. We strongly encourage women and
underrepresented minorities to apply. Cornell University is a recognized
EEO/AA employer and educator, valuing AA/EEO, Protected Veterans, and
Individuals with Disabilities.



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions at Icahn School of Medicine, Mount Sinai, New York, USA

[Cheng Zhang]

Happy New Year!

Post for a friend. Please contact Dr. Yi Shi at wally@gmail.com or
yi@mssm.edu if you are interested. Please help to pass the information
to your colleagues, students, or trainees.

Multiple postdoctoral positions are immediately available in Shi laboratory
of Proteomics, Center for Protein Engineering and Therapeutics at Icahn
School of Medicine at Mount Sinai in NYC.

The lab is interested in developing biotechnologies for the analysis of
biomolecules and macromolecular assemblies, with a focus on mass
spectrometry/proteomic techniques. Recently, inspired by the high
translational potential of the camelid single-chain antibodies (so-called
nanobodies), our lab has developed robust pipeline technologies and tools
to facilitate nanobody drug discovery and therapeutic applications. The lab
is also interested in the development and application of integrative
structural approaches to study protein-protein and antibody-protein
interactions. An emerging direction of the lab is to conjugate machine
learning, structural biology, and proteomic approaches to facilitate the
bioengineering and design of novel protein therapeutics and vaccines. The
lab is vibrant, fun, and collaborative, and supports creative ideas and
career development.

References:

Kim, S.J., et al (2018). Integrative structure and functional anatomy of a
nuclear pore complex. *Nature*.

Xiang, Y., et al (2020). Versatile and multivalent nanobodies efficiently
neutralize SARS-CoV-2. *Science*.

Nambulli., et al (2021). Inhalable Nanobody (PiN-21) prevents and treats
SARS-CoV-2 infections in Syrian hamsters at ultra-low doses. *Science
Advances*.

Xiang, Y., et al (2021). Integrative proteomics identifies thousands of
distinct, multi-epitope, and high-affinity nanobodies. *Cell Systems*.

Sun, et al. (2021). Potent neutralizing nanobodies resist convergent
circulating variants of SARS-CoV-2 by targeting novel and conserved
epitopes. *Nature Communications*.

Shen et al. (2021). A resource of high-quality nanobodies for drug
delivery. *iScience*.

Sang, et al. (2021) *Llamanade*: an open-source computational pipeline for
robust nanobody humanization. *Structure*.

Xiang et al (2022). Super-immunity by broadly protective nanobodies to
sarbecoviruses. *BioRxiv*.

Competitive salaries will be provided for successful candidates. Postdoc
housing is subsidized by the school of medicine. Motivated individuals
(Ph.D. or MD) with backgrounds in *mass spectrometry-based proteomics,
microbiology, structural biology (such as cryo-EM), and cancer
immunology* (ideally
with animal model experience) are particularly welcome to apply. Interested
candidates may submit their CVs, including names and contact information
for two-three references, a short description of their research experience,
and goals to Professor Yi Shi at (wally@gmail.com or yi@mssm.edu).

Visit our lab at: https://www.shi-lab.org/.

Some related news:

·Llama ‘nanobodies’ may yield COVID-19 treatment, Pitt scientists
say (The Philadelphia Inquirer)


·Why the lovable llama might be a secret weapon against
COVID-19 (Argonne National Library)


·COVID-19 breakthrough in llama nanobodies


·   Inhaled Nanobodies Protect Hamsters from COVID-19


·   Cheap, Potent Pathway to Pandemic Therapeutics


·Pitt Researchers Discover Llama ‘Nanobodies’ Are Powerful New
Coronavirus Treatment


·Pitt team discovers new way to find nanbodies to fight disease

[ccp4bb] Postdoc positions in cryoEM/ET at Princeton University

[John Jimah]

Hello everyone,

The Jimah lab at Princeton University 
(coming January 2022) is recruiting postdoctoral fellows. Interested applicants 
should apply online for projects on:

(1)   Cryo-EM and cryo-ET of malaria 
parasites
 or
(2)  Structural biology (cryo-EM) of membrane remodeling processes in human 
cells

The postdoctoral scholar will have access to cutting-edge cryo-EM equipment at 
the Imaging & Analysis Center and 
other instrumentation in various core facilities at Princeton University. The 
position is available starting January 2022 with a negotiable start date.
This position will be within the Molecular Biology Department, an innovative, 
vibrant, collegial, collaborative, and excellent research environment. 
Princeton University is in an idyllic town midway between New York City and 
Philadelphia, with convenient train access to both cities.

For more information, please contact Dr. Jimah by e-mail at ji...@princeton.edu

Best regards,
John




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions @ NIH

[Elmlund, Hans (NIH/NCI) [E]]

Hi Everyone,

The Biological Computing Section (BCS) Center for Structural Biology (CSB), 
National Cancer Institute (NCI)—Frederick campus are seeking to recruit four 
postdoctoral fellows. Link to ad below:

https://ccr.cancer.gov/careers/post-doctoral-fellow-electron-microscopy-image-processing-algorithm-development/24314

The job involves development of algorithmic solutions to address the increasing 
demands for quantitative and computational approaches in electron microscopy, 
integrative structural biology, and materials science. You will be working in a 
creative collaborative team developing and applying novel computational 
solutions for analyzing high-dimensional noisy image data.

Best wishes,

--
HANS ELMLUND PhD
Senior Investigator

National Institutes of Health
National Cancer Institute—Frederick Campus
1050 Boyles St, Fredrick MD 21702
United States of America

T:  +1(301)846-5670
M: +1(240)739-9079
E:  hans.elml...@nih.gov
simplecryoem.com



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions to explore the world of molecules!

[Marc Baaden]

Seeking 2 post-doctoral fellows with experience related to 
Biology/Bioinformatics, Unity3D, Virtual Reality or computer graphics to come 
to Paris.

View this email in your browser 
(https://mailchi.mp/83eaa9013f30/postdoc-positions-to-explore-the-world-of-molecules-10467202?epdc6ac29b)

Dear Colleagues,

Sorry for cross-posting and my apologies for contributing to filling your 
inbox. I am urgently looking for two new people to join my team and I am 
depending on your help. The positions I am looking to fill are very good 
positions in France, described below. They deal with immersive scientific 
visualization of membrane proteins, their assembly and omic data. Could you 
please forward this email to anyone you know who might be considered for this 
position? I would be very grateful for it.

Please let me know if you have any questions.

With best wishes,

Marc Baaden


** Come explore the world of molecules!

https://www.youtube.com/watch?v=Wp3_DPTXxew

I am seeking two post-doctoral fellows to start immediately in my lab. My lab 
is focused on the development of novel approaches for interactive visualization 
of molecular structures, including using UnityMol to create 3D user interfaces 
and Virtual Reality applications. The positions will involve the development of 
novel software components for high throughput molecular visualization, as well 
as challenging biological applications. We are looking for someone that is 
passionate about Molecular Biology who also has skills in computer programming 
and graphics design. See more details at the following links:
* immersive scientific visualization of membrane proteins and their assemblies 
(https://github.com/bam93/job-offers/tree/main/2021-postdoc-cofund) (PDF 
version) 
(https://github.com/bam93/job-offers/blob/f253ebf53ee209e2ac5368e0d34fd17f9c94bb80/2021-postdoc-cofund/job2021b.pdf)
* immersive scientific visualization of omic data 
(https://github.com/bam93/job-offers/tree/main/2021-postdoc-minomics) (PDF 
version) 
(https://github.com/bam93/job-offers/blob/f253ebf53ee209e2ac5368e0d34fd17f9c94bb80/2021-postdoc-minomics/job2021a.pdf)

More information about the institute and work environment is described through 
a series of short videos with testimonials and overviews 
(https://www.youtube.com/channel/UCB_u_mFVNM2mbbyUj7rwKmw) .

I hope you will be interested in joining our team!

Sincerely,

Marc Baaden



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions Leicester, UK

[Panne, Daniel (Prof.)]

Dear all,

We are looking for postdoctoral researchers to join our lab our lab at the 
Leicester Institute for Structural and Chemical Biology, UK. The positions are 
funded by a 5 year Wellcome Trust Investigator award to work on the regulation 
of gene expression and 3D genome organisation. For examples of recent work see 
Nature 578, 472–476 (2020); NSMB 27, 233–239 (2020); Nature 562, 538–544 (2018)

The successful candidates will use a multi-disciplinary approach that includes 
preparative biochemistry of multi-protein complexes, protein engineering and 
biophysical and structural techniques. The group is part of the Leicester 
Institute of Structural and Chemical Biology, UK. We have excellent access to 
state-of-the-art structural biology technologies including a Krios cryo-EM 
microscope

Please apply at: 
https://jobs.le.ac.uk/vacancies/2872/research-associate-structural-biology-of-genome-regulation.html

The advert closes on November 28!

If you have questions concerning this role, please contact me directly.
All the best,
Daniel

--

Daniel Panne
Professor of Structural Biology
Department of Molecular and Cell Biology
University of Leicester
Email: daniel.pa...@le.ac.uk



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] postdoc positions at the University of British Columbia (Vancouver, Canada)

[Filip Van Petegem]

Dear colleagues,



Two postdoctoral positions are available at The University of British
Columbia in Vancouver, Canada:



*Position 1:*



 A postdoctoral position is available immediately to work on ion channel
structural biology in the lab of Filip Van Petegem, Department of
Biochemistry and Molecular Biology.



The project combines X-ray crystallography, cryo-EM, and electrophysiology.
Our lab has steady access to the in-house X-ray and cryo-EM facilities:



- Microscopes: 300kV Titan Krios with Falcon IV detector and Selectris
Energy filter.   A 200kV Glacios (Falcon III detector) is available for
prescreening grids.

- X-ray equipment in the lab includes Mosquito and Dragonfly robotics, and
we have regular access to an in-house X-ray diffractor (Rigaku Micromax-007
HF with Saturn 744+ CCD detector) and various synchrotron beamlines



Minimum requirement for applicants include a PhD in Biochemistry or a
related discipline with extensive experience in either X-ray
crystallography or cryo-EM, as well as protein expression and
purification.  Direct experience with membrane proteins is an additional
plus.



The lab values diversity and inclusivity, and applicants from all
backgrounds are encouraged to apply. This is an opportunity for people with
structural biology expertise to learn electrophysiological methods.



Recent work from the lab includes an investigation of how Ryanodine
Receptors are modulated by small molecules, disease mutations, and
post-translational modification, using cryo-EM, X-ray crystallography,
planar lipid bilayer electrophysiology, and enzyme kinetics.

Woll et al (2021) *Nature Comm.* 12:807

Ma et al (2020) *Nat Chem Biol*. 16,1246-1254

Haji-Ghassemi et al (2019) *Molecular Cell* 75,1-14



For more information on recent work, see http://crg.ubc.ca/VanPetegem/



The lab is housed within the Life Sciences Centre at UBC (lsi.ubc.ca),
located on the Point Grey campus in Vancouver.



Interested candidates should send a CV, along with names and contact
details for 3 references to *filip.vanpete...@gmail.com
*.









--

*Position 2:*


A postdoctoral position is available to work on a joint project between the
labs of Filip Van Petegem and Robert Molday, both in the Department of
Biochemistry and Molecular Biology at the University of British Columbia.



The project will involve Cryo-EM on neuronal membrane proteins and will
make use of the excellent cryo-EM facility within the Life Sciences
Institute.  Microscopes available include a 300kV Titan Krios with Falcon
IV detector and Selectris Energy filter.   A 200kV Glacios (Falcon III) is
available for prescreening grids. The structural biology will be
complemented with various functional assays.



The ideal candidate will have a PhD in Biochemistry or a related
discipline, as well as extensive experience with either X-ray
crystallography and/or Cryo-electron microscopy. Direct experience with
membrane protein expression and mammalian cell cultures is an additional
asset.



The Molday and Van Petegem labs are housed within the Life Sciences
Institute (https://lsi.ubc.ca/).



For more information on the labs, see

http://crg.ubc.ca/VanPetegem/

and

https://biochem.ubc.ca/person/robert-molday/



Interested candidates should send a CV, along with names and contact
details for 3 references to both  mol...@mail.ubc.ca and
filip.vanpete...@gmail.com.



-- 
Filip Van Petegem, PhD
Professor, Dept. of Biochemistry and Molecular Biology
The University of British Columbia
2350 Health Sciences Mall - Rm 2.356
Vancouver, V6T 1Z3

phone: +1 604 827 4267
email: filip.vanpete...@gmail.com
http://crg.ubc.ca/VanPetegem/

Twitter: @FilipPetegem



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions on detergent-free membrane protein structural biology

[Youzhong Guo]

Hello Friends:

My lab has open positions for postdocs working on detergent-free membrane
protein structural biology.

The positions are supported by NIH grants and are available immediately. We
have been developing a detergent-free Native Cell Membrane Nanoparticles
system for membrane protein structural biology and related drug discovery.
We work on both technology development and biomedically or
biologically important membrane proteins.

Combined with single-particle cryo-EM and cryo-EM tomography
and other biochemical/biophysical characterization techniques, we are
investigating membrane proteins in their native cell membrane lipid
environment.

If you are interested in the positions, please email me directly at
yg...@vcu.edu.

Best,
Youzhong

Youzhong Guo
Assistant Professor of Medicinal Chemistry
Department of Medicinal Chemistry
Institute for Structural Biology, Drug Discovery and Development
Virginia Commonwealth University



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions Leicester, UK

[Panne, Daniel (Prof.)]

Dear all,

We are looking for postdoctoral researchers to join our lab our lab at the 
Leicester Institute for Structural and Chemical Biology, UK. The positions are 
funded by a 5 year Wellcome Trust Investigator award to work on the regulation 
of gene expression and 3D genome organisation. For examples of recent work see 
Nature 578, 472–476 (2020); NSMB 27, 233–239 (2020); Nature 562, 538–544 (2018)

The successful candidates will use a multi-disciplinary approach that includes 
preparative biochemistry of multi-protein complexes, protein engineering and 
state-of-the-art biophysical and structural techniques. The group is part of 
the Leicester Institute of Structural and Chemical Biology, UK. We have 
excellent access to state-of-the-art structural biology technologies including 
a Krios cryo-EM microscope

The advert closes on August 31st.

Please apply at: 
https://jobs.le.ac.uk/vacancies/2872/research-associate-structural-biology-of-genome-regulation.html

If you have questions concerning this role, please contact me directly.
All the best,
Daniel

--

Daniel Panne
Professor of Structural Biology
Department of Molecular and Cell Biology
University of Leicester
Email: daniel.pa...@le.ac.uk



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions in Cambridge

[Luca Pellegrini]

Dear all, 

A reminder that there are postdoc positions available in our lab in the 
Department of Biochemistry of the University of Cambridge, UK, to work on 
structure and function of protein complexes important for DNA replication and 
repair. The deadline for the application is April 2nd. 

Please apply at: https://www.jobs.cam.ac.uk/job/28616/ 
, and contact me directly for more 
information about the projects and the lab. 

Best wishes,
Luca

Luca Pellegrini, PhD
Department of Biochemistry
University of Cambridge
Cambridge CB2 1GA
UK






To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions in structural biology at Case Western Reserve University, Ohio

[Nami Tajima]

Postdoctoral positions in membrane protein structural biology are
immediately available in the Tajima Lab, in the Department of Physiology
and Biophysics at Case Western Reserve University School of Medicine. We
seek self-motivated and creative structural biologists.


We focus on

1. understanding the molecular mechanisms of ion channels that play a
pivotal role in synaptic transmission.

2. dissecting the signaling pathways in the CNS in health and disease.

3. structure-based drug discovery.


These issues will be addressed using a multidisciplinary approach,
including structural biology, patch-clamp electrophysiology, molecular and
cellular biology, and biochemistry/biophysics. Case Western Reserve
University is equipped with a state-of-art structural biology facility,
including FEI Titan Krios (with phase plate, energy filter, and a K3
detector), FEI Tecnai TF20 & T12 screening microscopes, and the
high-performance data analysis infrastructure. The department also has core
facilities for protein expression/purification, X-ray crystallography,
proteomics&mass spectrometry, and electrophysiology. The successful
candidates will enjoy a collaborative environment with cutting-edge
instruments.


Applicants should hold (or will be shortly awarded) a PhD degree and have
experience in molecular biology and protein purification. Experience in
single-particle Cryo-EM/X-ray crystallography is probably a better fit for
this position. Please send a cover letter describing research interests, a
CV, and contact information for 2-3 references to Nami Tajima at
nxt...@case.edu.


Additional information about the group can be found here:

https://sites.google.com/case.edu/tajimalab/home

https://physiology.case.edu/people/faculty/nami-tajima/


Many thanks and best wishes,

Nami

***
Nami Tajima, Ph.D.
Assistant Professor
Department of Physiology and Biophysics
Case Western Reserve University School of Medicine
2109 Adelbert Road, Robbins Bldg E619
Cleveland, OH 44106
nxt...@case.edu
Office: 216-368-5519
Cell: 516-655-9045
***



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions in structural analysis of trypanosome kinetochores, University of Oxford

[Bungo Akiyoshi]

Dear Colleagues,

Two postdoc positions are available in my group at the Department of 
Biochemistry, University of Oxford.

We are seeking to appoint two outstanding individuals with PhD training in 
structural biology to reveal the structure and function of unconventional 
kinetoplastid kinetochore proteins. Although it was widely believed that all 
eukaryotes would have a conserved set of kinetochore proteins, we identified 
more than 20 uncharacterized kinetochore proteins (named KKT1–25) in 
Trypanosoma brucei and discovered that they constitute unconventional 
kinetochores specific to kinetoplastids, a group of evolutionarily-divergent 
eukaryotes (Akiyoshi and Gull, Cell 2014, Nerusheva and Akiyoshi Open Biol 
2016, Nerusheva et al., Open Biol 2019, Tromer et al., bioRxiv 2021). We are 
currently characterizing these KKT proteins using various techniques including 
cell biology, bioinformatics, super-resolution microscopy, biochemistry, 
biophysics, and structural biology (X-ray crystallography, NMR, electron 
tomography, and cryoEM/ET).

For more information, please click on the link below:
https://my.corehr.com/pls/uoxrecruit/erq_jobspec_version_4.jobspec?p_id=149534

Please contact me if you have any question.

Best wishes,
Bungo

--
Bungo Akiyoshi, PhD
Wellcome Trust Senior Research Fellow, EMBO YIP
Department of Biochemistry, University of Oxford
https://bungoakiyoshi.com/




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc Positions at Princeton University

[Alexei Korennykh]

Dear Finishing Graduate Students,

Postdoc positions are available in my group immediately or when you are 
ready.


Research topics: antiviral immune system, mammalian stress response, RNA 
biology, structural biology of emerging mitochondrial pathways.
Methods we use: X-ray crystallography, Cryo-EM, RNA and protein 
biochemistry, RNA-seq, mammalian cell biology, CRISPRs.
If you have background and interest in one or more of these areas, you 
are most welcome to send an email directly to Alexei:

akore...@princeton.edu

To get familiar with our work:
https://pubmed.ncbi.nlm.nih.gov/?term=Korennykh&sort=date

Prof. Alexei Korennykh.
Department of Molecular Biology
Princeton University



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] PostDoc Positions at CCP-EM/STFC and the Alan Turing Institute

[Burnley, Tom (STFC,RAL,SC)]

Dear all,

We are excited to announce that two PostDoc positions in cryoEM software 
methods development.

One is at STFC with the CCP-EM and Scientific Machine Learning Group (SciML) 
and a second in Alan Lowe's group 
(https://www.ucl.ac.uk/biosciences/people/lowe-alan).  These are part of a 
wider collaboration with Scheres (LMB) and Schönlieb (Cambridge) groups to use 
machine learning to improve cryoEM reconstructions:

https://www.turing.ac.uk/research/research-projects/molecular-structure-images-under-physical-constraints

CCP-EM/STFC details and position can be found here:

https://careersportal.co.uk/UKRI-careers/jobs/data-scientist-senior-data-scientist-195

UCL/Turing details and position can be found here:

https://cezanneondemand.intervieweb.it/turing/jobs/research_associate__molecular_biology_11738/en/

For informal enquires / further information do please contact myself or Alan 
Lowe (CC'd).

Best wishes,

Tom and Alan


This email and any attachments are intended solely for the use of the named 
recipients. If you are not the intended recipient you must not use, disclose, 
copy or distribute this email or any of its attachments and should notify the 
sender immediately and delete this email from your system. UK Research and 
Innovation (UKRI) has taken every reasonable precaution to minimise risk of 
this email or any attachments containing viruses or malware but the recipient 
should carry out its own virus and malware checks before opening the 
attachments. UKRI does not accept any liability for any losses or damages which 
the recipient may sustain due to presence of any viruses. Opinions, conclusions 
or other information in this message and attachments that are not related 
directly to UKRI business are solely those of the author and do not represent 
the views of UKRI.




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc Positions available at Shanghai Jiao Tong University

[yanwup...@hotmail.com]

Dear all,

Two postdoc positions are available in Dr. Wupeng Yan’s newly established lab 
Shanghai Jiaotong University in Shanghai, China.

The lab is utilizing multiple approaches including biochemistry, biophysics, 
and structural biology to investigate enzyme structure and functions, protein 
engineering as well as understand the molecular mechanism of oncogenic mutation 
RAS with its downstream effectors. We are currently looking for candidates who 
are highly motivated, creative with excellent writing and communication skills 
to join our team.

The candidates should received their ph.D degree within 3 years in 
Biochemistry, Molecular Biology, Structural Biology or related fields. 
Successful candidates should have experience in one or more field including 
molecular cloning, protein expression and purification, enzyme function assay, 
ITC/SPR and X-ray crystallography, as evidenced by a record of first-author 
publications in peer-reviewed journals. Experience with cryo-EM/NMR is not 
required, but would be advantageous.

The salary for the position would be at least 240,000 CNY annually, additional 
bonus is available for outstanding postdoc fellows. Benefits includes 
insurance, low-rent housing near campus and funding opportunities are also 
encouraged. For more details, please check the website of the university 
https://postd.sjtu.edu.cn/Home/Home.htm.

Shanghai Jiao Tong University (SJTU), is one of the best research institutions 
which enjoy a long history and a world-renowned reputation in China. The city 
of Shanghai is also among the top cities in China which is a global financial 
center and transport hub with an excellent international styled culture.

Interested candidates please send their applications including CV, contacts for 
3 referees and a brief cover letter by e-mail to yanwup...@sjtu.edu.cn.


Best,

Wupeng Yan
Tenure Track Associate Professor
School of Life Sciences and Biotechnology
Shanghai Jiao Tong University
800 Dongchuan RD. Minhang District, Shanghai, China




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions at Monash University

[Alex de Marco]

Hi All,
I have 3 open postdoc positions in my group starting from March 2021.
The work will focus on in situ structural biology (2x) and image
processing/software development (1x).
I am looking for people with experience in one or more of the following:
cryoFIB, cryoET, CLEM.
The software development position will heavily focus on image processing
but does not need to have prior cryoEM experience, although it would help.
Anyone interested, please contact me directly and send me a CV.

Cheers
Alex



-- 

*Alex de Marco, PhD*

Associate Professor



Monash University

*Dept. of Biochemistry and Molecular Biology*

*ARC Centre of Excellence in Advanced Molecular Imaging*

23 Innovation Walk, 3800 Clayton (Australia)

P: +61 3 99053791 <%2B61%2003%2099053791>

M: *+61 4 11041429*

Email: alex.dema...@monash.edu

Web: www.demarco-lab.com



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

Re: [ccp4bb] Postdoc positions at MRC-LMB & CCPEM/STFC

[Burnley, Tom (STFC,RAL,SC)]

Dear all,

A gentle reminder that the deadlines for applications are due this week... 
Friday 23 October for the STFC/CCP-EM position and Sunday 25 October for the 
MRC-LMB position.

Best wishes,

Tom and Sjors


From: CCP4 bulletin board  on behalf of Burnley, Tom 
(STFC,RAL,SC) 
Sent: 25 September 2020 13:21
To: ccp4bb 
Subject: [ccp4bb] Postdoc positions at MRC-LMB & CCPEM/STFC

Dear all,

For those interesting in computational cryoEM development...

We are excited to announce two new PDRA positions in the Scheres’ group 
(MRC-LMB, UK) and the CCP-EM group (STFC RAL, UK).  These two positions will 
work closely together as part of a wider project with the Alan Turing Institute 
and the Department of Applied Mathematics and Theoretical Physics at Cambridge 
University to investigate molecular structure from images under physical 
constraints.

In brief, the LMB position will focus on developing and implementing new 
machine-learning-driven algorithms within the RELION framework.  The STFC 
position will focus on the data capture and training for these algorithms (as 
well as for the wider community), alongside application to molecular modelling. 
 For full details and application please see:

LMB position:

https://mrc.tal.net/vx/lang-en-GB/mobile-0/appcentre-1/brand-3/xf-15f5592f8769/candidate/so/pm/4/pl/1/opp/1377-Postdoctoral-Scientist-Structural-Studies-Dr-Sjors-Scheres-LMB-1377/en-GB

STFC position:

https://www.topcareer.jobs/Vacancy/irc255076_10934.aspx

For those interested in both positions, we encourage you to apply for both. If 
you are unsure or would like further information please contact us.

Best wishes,

Tom and Sjors

This email and any attachments are intended solely for the use of the named 
recipients. If you are not the intended recipient you must not use, disclose, 
copy or distribute this email or any of its attachments and should notify the 
sender immediately and delete this email from your system. UK Research and 
Innovation (UKRI) has taken every reasonable precaution to minimise risk of 
this email or any attachments containing viruses or malware but the recipient 
should carry out its own virus and malware checks before opening the 
attachments. UKRI does not accept any liability for any losses or damages which 
the recipient may sustain due to presence of any viruses. Opinions, conclusions 
or other information in this message and attachments that are not related 
directly to UKRI business are solely those of the author and do not represent 
the views of UKRI.



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc Positions in Protein Engineering at Rice University

[George Lu]

Dear colleagues,

We have several openings for postdoctoral fellows. Please see the 
advertisement below.




The Lab for Synthetic Macromolecular Assemblies  
(PI: George J. Lu) at Rice Bioengineering has multiple openings for 
postdoctoral fellows. The research focuses on the understanding and 
engineering of a class of gas-filled protein nanostructures named gas 
vesicles, and use them to develop novel imaging and cellular control 
technologies for basic research and cell therapies. Gas vesicles were 
recently shown to enable ultrasound- and MRI-based imaging of gene 
expressions in therapeutic microbes and mammalian cells (Nature 
Materials 2018 ; Nature 
Protocols 2017 ; Nature 2018 
; Science 2019 
), and have future applications 
in remote cellular control and biomaterials. The qualified postdoc 
researchers recruited here will lead projects in understanding the 
molecular mechanism of gas vesicles, engineering novel genetic variants, 
and developing imaging and cellular control platforms that incorporate 
these agents.


Dr. Lu was previously awarded the Young Investigator of the Year 
 
from the World Molecular Imaging Society for his work on the development 
of acoustically erasable MRI reporter genes. The independent lab was 
newly established in 2020 with the support of the NIH 
Pathway-to-independence (K99/R00) 
 
and the Cancer Prevention and Research Institute of Texas (CPRIT) 
Scholar  
awards.


The ideal candidate will have strong expertise in one or several of the 
following areas: protein structural biology, computational protein 
design, directed evolution and high-throughput screening, microbial 
engineering, mammalian synthetic biology, and ultrasound imaging. The 
candidate should have strong written and oral communication skills, and 
will also be expected to aid in the supervision of junior lab members 
and in the preparation of research proposals. The application for 
postdoctoral fellowships will be encouraged, including both external and 
internal ones such as Rice University Academy of Fellows. The pay scale 
for the position follows NIH guidelines.


Rice Bioengineering is one of the top biomedical engineering departments 
with its graduate program consistently ranked among the top 10 in the 
country. The candidate will have opportunities to lead cutting-edge 
research projects and interact with outstanding scientists as 
collaborators and trainees.


//

Rice University is an Equal Opportunity Employer with commitment to 
diversity at all levels, and considers for employment qualified 
applicants without regard to race, color, religion, age, sex, sexual 
orientation, gender identity, national or ethnic origin, genetic 
information, disability, or protected veteran status.


To apply, please visit https://jobs.rice.edu/postings/24661 or email a 
cover letter and a copy of CV/resume to george...@rice.edu 
.





Best,
George

George J. Lu, PhD
Assistant Professor of Bioengineering
CPRIT Scholar in Cancer Research
Rice University
http://lulab.rice.edu






To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions at MRC-LMB & CCPEM/STFC

[Burnley, Tom (STFC,RAL,SC)]

Dear all,

For those interesting in computational cryoEM development...

We are excited to announce two new PDRA positions in the Scheres’ group 
(MRC-LMB, UK) and the CCP-EM group (STFC RAL, UK).  These two positions will 
work closely together as part of a wider project with the Alan Turing Institute 
and the Department of Applied Mathematics and Theoretical Physics at Cambridge 
University to investigate molecular structure from images under physical 
constraints.

In brief, the LMB position will focus on developing and implementing new 
machine-learning-driven algorithms within the RELION framework.  The STFC 
position will focus on the data capture and training for these algorithms (as 
well as for the wider community), alongside application to molecular modelling. 
 For full details and application please see:

LMB position:

https://mrc.tal.net/vx/lang-en-GB/mobile-0/appcentre-1/brand-3/xf-15f5592f8769/candidate/so/pm/4/pl/1/opp/1377-Postdoctoral-Scientist-Structural-Studies-Dr-Sjors-Scheres-LMB-1377/en-GB

STFC position:

https://www.topcareer.jobs/Vacancy/irc255076_10934.aspx

For those interested in both positions, we encourage you to apply for both. If 
you are unsure or would like further information please contact us.

Best wishes,

Tom and Sjors

This email and any attachments are intended solely for the use of the named 
recipients. If you are not the intended recipient you must not use, disclose, 
copy or distribute this email or any of its attachments and should notify the 
sender immediately and delete this email from your system. UK Research and 
Innovation (UKRI) has taken every reasonable precaution to minimise risk of 
this email or any attachments containing viruses or malware but the recipient 
should carry out its own virus and malware checks before opening the 
attachments. UKRI does not accept any liability for any losses or damages which 
the recipient may sustain due to presence of any viruses. Opinions, conclusions 
or other information in this message and attachments that are not related 
directly to UKRI business are solely those of the author and do not represent 
the views of UKRI.




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] Postdoc positions at Princeton

[Alexei Korennykh]

Dear Students looking for postdoc opportunities:

My lab at Princeton University invites postdoc candidates to join a 
collegial research group working on


Antiviral innate immunity
Mammalian stress response
Translational regulation
Mitochondrial circadian biology
Structural biology (X-ray and high resolution cryo-EM)
RNA biology

Some reading about our lab
https://pubmed.ncbi.nlm.nih.gov/?term=korennykh&sort=date&size=50
https://scholar.princeton.edu/korennykhlab/home

If interested send me an email with a brief description of yourself and 
your current research:


akore...@princeton.edu

I look forward to hearing from you.
Alexei.




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/

[ccp4bb] PostDoc positions

[Albert Guskov]

Dear all,
I have two PostDoctoral openings in my group.
Position #1 - a 3 year PostDoc position in time-resolved crystallography on
membrane proteins, based at the University of Groningen, however the nature
of this position will require a lot of travelling for synchrotron and XFEL
measurements.
For this position we are looking for a recent PhD graduate with hands-on
experience in membrane protein crystallography and experience in
synchrotron and /or XFEL data collection and data  processing.

Position #2 - a 3 year PostDoc position in single particle cryo-EM on
membrane proteins, based primarily at the Moscow Institute of Physics and
Technology but with visits to the lab in Groningen as well.

For this position we are looking for a recent PhD graduate with hands-on
experience in membrane protein production (bacterial expression hosts or
LEXSY) / purification and desirably some experience in single particle
cryo-EM. The working language of the Institute is English, but knowledge of
Russian can be helpful in everyday life. The Russian courses  can be
arranged if necessary.


If you are interested, please send your CV and a motivation letter
to a.guskov at rug.nl (for position #1)
and to guskov.ai at phystech.edu (for position #2)

Albert Guskov (Dr rer nat)
Head of  Biomolecular X-ray Crystallography lab | University of Groningen
Head of Cryo-EM lab | Moscow Institute of Physics and Technology



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1

[ccp4bb] Postdoc positions at Imperial College London with Prof. Dale Wigley

[Wilkinson, Martin]

Job Advertisement Title: Research Associate in Structural Biology

Salary: £40,215 - £47,579

Location: South Kensington Campus

Job Summary

We are recruiting for two Research Associates in the Section of Structural 
Biology at South Kensington in the research group of Professor Dale Wigley 
(https://www.structurebiomed.org/dale-wigley). The successful candidate will 
join a multi-disciplinary team of international researchers investigating the 
structures and mechanisms of chromatin modifying complexes in human DNA damage 
repair and cancer. We combine structural biology techniques with biochemistry 
to understand molecular mechanisms for DNA repair that prevent cancer in 
humans. The successful candidates will have proven expertise in either or both 
of these areas.

You must hold a PhD, or equivalent, in biochemistry, enzymology or structural 
biology and have a demonstrated track record in conducting high quality 
original research. Knowledge at postgraduate level in structural biology 
(crystallography or electron microscopy) and/or biochemistry is essential and 
experience in expression/purification of multi-protein complexes in insect or 
human cells is desirable.

For informal enquiries please contact Professor Dale Wigley 
d.wig...@imperial.ac.uk.


Closing date: 21/11/2019

For technical issues when applying online please email 
recruitm...@imperial.ac.uk

The College is a proud signatory to the San-Francisco Declaration on Research 
Assessment (DORA), which means that in hiring and promotion decisions, we 
evaluate applicants on the quality of their work, not the journal impact factor 
where it is published. For more information, see 
https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/

The College believes that the use of animals in research is vital to improve 
human and animal health and welfare. Animals may only be used in research 
programmes where their use is shown to be necessary for developing new 
treatments and making medical advances. Imperial is committed to ensuring that, 
in cases where this research is deemed essential, all animals in the College’s 
care are treated with full respect, and that all staff involved with this work 
show due consideration at every level.

http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research/

Imperial College is committed to equality of opportunity, to eliminating 
discrimination and to creating an inclusive working environment. We are an 
Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability 
Confident Employer and work in partnership with GIRES to promote respect for 
trans people.


———

Dr Martin Wilkinson
mwilk...@ic.ac.uk

Imperial College
Lab 245
2nd Floor, SAF building
Imperial College Road
London
SW7 2AZ
———


———
Dr Martin Wilkinson
mwilk...@ic.ac.uk

Imperial College
Lab 245
2nd Floor, SAF building
Imperial College Road
London
SW7 2AZ
———




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1


Ad PDRA_2.docx
Description: Ad PDRA_2.docx

[ccp4bb] PostDoc Positions in Cryo-EM

[Stefan Raunser]

Dear colleagues,
I would like to draw your attention to the following job opportunities.
Best
Stefan

PostDoc Positions (m/f/d) in Cryo-EM
SCIENTIST DORTMUND
Structural and Cell Biology

Max Planck Institute of Molecular Physiology seeks to fill PostDoc Positions in 
Cryo-EM  (m/f/d).

The positions are available immediately in the Department of Structural 
Biochemistry (Director: Stefan Raunser) and are initially limited to 2 years.

Job description: Our research focuses on structural and functional studies of 
macromolecular protein complexes by single particle electron cryo-microscopy 
(cryo-EM), electron cryotomography (cryo-ET), X-ray crystallography, 
biochemical and biophysical methods. There are three projects available in the 
lab concentrating on the structural organization of muscles, cytoskeletal 
proteins and bacterial toxin complexes using single particle cryo-EM and/or 
cryo-ET.

Requirements: The successful candidates hold an excellent PhD in structural 
biology, biochemistry, biophysics or physics. Experience in electron 
microscopy, in particular single particle cryo-EM or cryo-ET is not essential 
but will be considered highly advantageous. Strong written and oral 
communication skills in English and excellent computational skills are required.

Payment: Payment of Postdocs depends on personal conditions and qualification 
according to the directive of TVöD. Social benefits correspond to those of the 
public service.

Application: The Max Planck Society (MPG) is committed to increasing the number 
of individuals with disabilities in its workforce and therefore encourages 
applications from such qualified individuals.

The MPG seeks to increase the number of women in those areas where they are 
underrepresented and therefore explicitly encourage women to apply.

Furthermore the MPG strives for gender equality and diversity within its 
workforce.

Please send your CV, two references and a statement outlining your interests 
and relevant work experience until November 08, 2019 to Stefan Raunser at 
raunser-jobsea...@mpi-dortmund.mpg.de



---
Prof. Dr. Stefan Raunser | Director | Dep. Structural Biochemistry | Max Planck 
Institute of Molecular Physiology | Otto-Hahn-Straße 11, 44227 Dortmund, 
Germany | +49 231 133 2300




To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1

[ccp4bb] postdoc positions at Birkbeck College, London

[Giulia Zanetti]

Dear all,

I will soon be able to officially advertise two post-doctoral positions to work 
on biochemistry, cryo-tomography and subtomogram averaging studies of the COPII 
coat.

I encourage anybody interested in knowing more about the projects and the lab 
to contact me at: g.zane...@mail.cryst.bbk.ac.uk

We are based at Birkbeck College in London, which hosts a great EM facility and 
supports a vibrant EM community.

Looking forward to hearing from many cryo-tomography and/or membrane 
trafficking enthusiasts!

 

Giulia

 

https://www.zanettilab.co.uk


To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1

[ccp4bb] Postdoc positions in Luca Lab at Moffitt Cancer Center

[Vince Luca]

Dear all,

Our laboratory (www.thelucalab.org) is recruiting postdoctoral researchers
interested in (1) studying the structural mechanisms of Notch receptor
activation and (2) designing biologics to control Notch activity on
specific tissue types. We use a multidisciplinary approach that integrates
structural and cellular biology with cutting edge protein engineering
techniques, such as directed evolution, to understand signaling mechanisms
at the molecular level. These projects incorporate both basic and
translational research, and Notch-targeted biologics will be evaluated as
potential therapies for autoimmunity, developmental disorders, and cancer.
Candidates will work with a team of immunologists, tumor biologists, and
clinicians at Moffitt Cancer Center (Tampa, FL) to conduct research in a
highly collaborative environment. The positions are funded for up to 5
years by an R35 MIRA grant from the NIH/NIGMS.

Ideal candidates have demonstrated expertise in protein biochemistry and
molecular biology. Expertise in x-ray crystallography and protein or
antibody engineering is preferred.

*Position highlights*
- Structure-function studies of Notch receptor signaling mechanisms
- Design biologics using protein engineering and directed evolution
- Collaboratively assess the therapeutic potential of biologics in disease
models

*Responsibilities*
- Protein purification, biophysical characterization of protein-protein
interactions, directed evolution, x-ray crystal structure determination,
cellular signaling assays
- Mentor graduate students and technicians
- Compose manuscripts and postdoctoral fellowships, assist with grant
applications

*Credentials and qualifications*
- PhD in Structural Biology, Molecular Biology, Biophysics, or a related
field (required)
- PhD awarded within the past year (preferred)

*How to apply*
Candidates should e-mail the following to vince.l...@moffitt.org:
1) A cover letter that describes their motivation to pursue this position
and summarizes past research accomplishments.
2) A current CV with recent publications and contact information for three
references.

*Moffitt Cancer Center Overview*
Moffitt Cancer and Research Institute is a rapidly expanding,
NCI-designated comprehensive cancer center that includes state of the art
core facilities to support basic research. The Moffitt Chemical Biology
Core is equipped with a Rigaku X-ray diffraction system and labs have
regular access to the Advanced Photon Source Synchrotron (SER-CAT
beamlines) for remote data collection. The Core also includes a Biacore
T200, Nanotemper MST, Microcal ITC for analyzing protein-protein
interactions and Mosquito crystallization robot for automated screening.
Moffitt Cancer Center is located within the coastal community of Tampa Bay
and is adjacent to the University of South Florida School of Medicine.

Best,
Vince

-- 
Vincent C. Luca, PhD.
Principal Investigator
Department of Drug Discovery
Moffitt Cancer Center & Research Institute
12902 USF Magnolia Dr
Tampa, FL 33612
www.thelucalab.org



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1

[ccp4bb] postdoc positions - cryoEM - NYC

[Amedee des Georges]

Dear CCP4ists,

My group is seeking highy motiviated applicants for two post-doctoral research 
associate positions, available immediately. Both projects are geared towards 
understanding the effect of ligands on membrane protein dynamics using cryo-EM 
and image analysis methods. One is funded by an American Heart Association 
Innovative Research Award and the other by the Pharma company Servier.

We are located at the CUNY Advanced Science Research Center (ASRC), in the 
heart of Manhattan. The ASRC offers a highly interactive and collaborative 
environment that integrates structural biologists with colleagues in 
neuroscience, photonics, nanoscience and environmental sciences. Combining 
world-class experts in these areas with state-of-the-art instrumentation both 
at the ASRC and at the adjacent New York Structural Biology Center, including 
several FEI Titan cryo-electron microscopes, the ASRC offers a unique 
opportunity for research programs to flourish among normally-disparate fields.

Our laboratory studies the structure, function and dynamics of macromolecular 
complexes involved in cell homeostasis using cryo-electron microscopy. We are 
looking for applicants with experience in structural and molecular biology. 
Knowledge of model-building and molecular dynamics are a plus, but experience 
in electron microscopy is not required.

Please feel free to share this with interested parties.

Best,

Amedee des Georges

--
Amedee des Georges, Ph.D.
Assistant Professor, Structural Biology Initiative, CUNY Advanced Science 
Research Center
Assistant professor of Chemistry & Biochemistry, City College of New York
amedee.desgeor...@asrc.cuny.edu - 
http://asrc.cuny.edu  -  212-413-3232





To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1

[ccp4bb] Postdoc positions at the Yale University, School of Medicine

[Sangwon Lee]

The Lee lab in the Department of Pharmacology at the Yale School of Medicine 
has an immediate opening for a highly motivated Postdoctoral Associate to 
investigate the molecular mechanism of endocrine Fibroblast Growth Factor (FGF) 
signaling. Endocrine FGFs, which include, FGF15/19, FGF21, and FGF23, activate 
signaling via FGF receptors and require binding to the Klotho family of surface 
receptors; FGF23 signaling requires α-Klotho, while FGF15/19 and FGF21 
signaling requires β-Klotho. The research in our laboratory is focused on the 
structural elucidation, biophysical and biochemical analyses of complexes 
involved in endocrine FGF signaling.

Applicants should have a PhD in biochemistry, biophysics or a related field and 
should have extensive experience in recombinant protein production, as well as 
excellent written and oral communication skills. Experience in structural 
biology techniques (X-ray crystallography or cryo-EM), mammalian cell culture 
and quantitative biophysical analyses are also desirable, but not necessary.

Interested candidates should send a current CV, a statement of research 
interests, and the names and contact information of two references to Sangwon 
Lee (s@yale.edu).



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1

[ccp4bb] Postdoc positions at MRC LMB, Cambridge

[Andrew Carter]

Dear All

I am advertising for two postdoc positions in my lab.  Our overall goal 
is to understand how the motor dynein selects its many cargos.


One post would suit someone with good biochemical skills and training in 
X-ray crystallography who wants to learn cryoEM.


https://www.nature.com/naturecareers/job?id=674061

The other position is for an individual who is interested in 
implementing and/or developing cryo-EM or cryo-ET image analysis 
techniques to study flexible molecular machines.  I am looking for 
someone with a strong background in scripting and/or algorithm 
development.  A desire to learn the practical aspects of cryoEM would be 
an advantage.


https://www.nature.com/naturecareers/job?id=674065


The closing date for both applications is 3rd March 2019.  Please feel 
free to contact me if you have any questions (cart...@mrc-lmb.cam.ac.uk).


Best wishes

Andrew



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1

[ccp4bb] Postdoc positions in structural biology and single-molecule biophysics

[Sebastian Deindl]

Dear all,

We’re currently looking to hire two postdoctoral researchers with a background 
in cryo-EM, X-ray crystallography, or single-molecule biophysics to join our 
ERC-funded research project at SciLifeLab Uppsala/Stockholm 
(deindl-lab.com).

Our group utilizes structural and single-molecule approaches to characterize 
the dynamics, structure, and regulation of chromatin-associated protein 
machines.

For more information, please see 
https://www.nature.com/naturejobs/science/jobs/650913-postdoctoral-position-in-structural-biology-or-single-molecule-biophysics.


Best,

Sebastian


=
Sebastian Deindl, Ph.D.
Associate Professor
Wallenberg Academy Fellow

Department of Cell and Molecular Biology
Uppsala University
Phone: +46 (0) 18 471 6681
Email: sebastian.dei...@icm.uu.se

Web: http://deindl-lab.com








När du har kontakt med oss på Uppsala universitet med e-post så innebär det att 
vi behandlar dina personuppgifter. För att läsa mer om hur vi gör det kan du 
läsa här: http://www.uu.se/om-uu/dataskydd-personuppgifter/

E-mailing Uppsala University means that we will process your personal data. For 
more information on how this is performed, please read here: 
http://www.uu.se/om-uu/dataskydd-personuppgifter/



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1

[ccp4bb] Postdoc positions at RCSB PDB, UC San Diego

[Jose Duarte]

Two postdoctoral positions are available for talented and highly motivated
individuals interested in joining our multidisciplinary team at UC San
Diego/San Diego Supercomputer Center.


*Postdoctoral Fellow: 3D Visualization and Analysis*

Develop innovative scientific visualization and analysis tools for 3D
biomolecular structures to help accelerate research in biology, medicine,
and related disciplines. Your work will extend Mol* and MolQL to reach a
wide audience when deployed as interactive features.

Areas of focus include:

Innovative representations for 3D structural data from integrative/hybrid
methods
Visualizations for comparative analyses of molecular structures and
sequences
GPU acceleration of analysis and visualization algorithms
Multiscale rendering and data delivery for exploring large
structures/complexes

Requirements

PhD: Structural Bioinformatics or related field with a focus on software
development or
PhD: Computer Science with a focus on scientific visualization and/or
biology
Demonstrated proficiency in JavaScript/TypeScript as a general-purpose
programming language and experience with state-of-the-art software
development. Strong skills in problem solving and algorithm design are
required. High productivity and independence demonstrated by publications
and contributions to open source software projects is a plus. Experience in
the development of modern web applications, user interface design, or
scientific visualization is a plus. Experience with writing GPU shaders a
plus. Good written and oral communication skills.


*Postdoctoral Fellow: Bioassembly/Machine Learning*

Improve the representation and findability of biological assemblies in the
PDB, using innovative algorithms to build the next generation search engine
for molecular biology.

Areas of focus include:

Machine learning
Efficient search algorithms
Scalability of solutions across large datasets

Requirements

PhD: Computer Science with a focus on bioinformatics or machine learning or
PhD: Structural Bioinformatics or Biology, or related field with a focus on
software development
Demonstrated proficiency in a high-level programming language, such as
Java, Python, C++ and experience with state of the art software engineering
tools. Strong skills in problem solving and algorithm design are required.
A background in NoSQL database technologies would be beneficial. Experience
in the development of modern web applications, user interface design, or
scientific visualization is a plus. We expect candidates to have shown high
productivity demonstrated by publications and contributions to open source
software projects. Excellent written and oral communication skills are
required.


*About RCSB PDB*
RCSB Protein Data Bank is a world-renowned, scientific organization focused
on serving technical, educational and other programmatic needs of
scientific and research communities worldwide. RCSB.org serves more than 1
million users in academia and industry. The RCSB PDB development team
creates leading edge web technologies targeted for scientific and
educational audiences.

*About UCSD/SDSC*
RCSB PDB is located in the Skaggs School of Pharmacy at UC San Diego.

UC San Diego is recognized as one of the largest employers in San Diego
county with outstanding benefits and a diverse community of faculty, staff
and students. As an Organized Research Unit of UC San Diego, the San Diego
Supercomputer Center (SDSC) is a world leader in data-intensive computing
and cyber infrastructure, providing resources, services, and expertise to
the national research community, including industry and academia.

Details of UC San Diego's Postdoc compensation, including salary ranges,
are online. UC San Diego is an equal opportunity employer and both foreign
and domestic applicants are encouraged to apply.



More information and how to apply at http://www.rcsb.org/pages/jobs

[ccp4bb] postdoc positions - Structural and Chemical biology of new drug targets for Alzheimer

[Opher Gileadi]

Postdoctoral Scientist - Structural Biology (2 posts)

SGC, Nuffield Department of Medicine (NDM), Old Road Campus Research Building, 
Roosevelt Drive, Headington, Oxford OX3 7DQ
Grade 7: Salary in the range £31,604 - £33,518 p.a.

For full details and application links see:
http://www.thesgc.org/careers/oxford/sgc-oxford-postdoctoral-scientist-structural-biology-2-posts

We are seeking two postdoctoral scientists with expertise in protein 
crystallography and biochemistry to explore new potential drug targets for 
treatment or prevention of dementia.

The Accelerating Medicines Partnership - Alzheimer's Disease (AMP-AD, 
www.nia.nih.gov/research/amp-ad) is an ambitious project funded by the US 
National Institute of Health, pharmaceutical companies and non-profit 
organisations. It integrates data from RNA, protein and metabolomics 
measurements in brain samples, network analysis and pathway modelling, to 
identify potential new drug targets and biomarkers for Alzheimer treatment and 
prevention. In its second phase, a selected set of targets are moved forward to 
further validation studies. The Gileadi group has extensive experience in 
structure and chemical biology of novel human proteins, and enjoys access to 
technologies for structure-guided chemical development for new target classes,

The two postdoctoral scientist roles will each be responsible for a diverse set 
of novel candidate target genes: In particular, develop methods for expression 
and purification of the target proteins, structural analysis by crystallography 
and other methods, biochemical activity assays, and identification of ligands 
by screening and structure-guided approaches, including the 
crystallography-based fragment screen 
(www.diamond.ac.uk/Beamlines/Mx/Fragment-Screening.html)

You will be educated to PhD degree level in structural biology or possess 
equivalent experience (or be close to completion of a PhD). Proven experience 
in protein biochemistry and crystallography would be essential. In addition, 
the ability to plan and perform experiments independently. You will be able to 
work as part of a multidisciplinary team and be well-organised in planning and 
documenting experiments.

The two posts are full-time and available on a fixed-term contract until 31 
August 2019 in the first instance.

You will be required to upload a CV and supporting statement which explains how 
you meet the selection criteria for the post.

Only applications received before 12.00 noon on 5 February 2018 will be 
considered.
Contact Person :HR Officer - RecruitmentVacancy ID :132792
Contact Phone : 01865 617971Closing Date :  05-Feb-2018
Contact Email : orcrb.person...@ndm.ox.ac.uk

[ccp4bb] PostDoc positions in Membrane Protein Structural Biology

[David Drew]

Dear all,

We are looking for two highly motivated Post-Docs with a Ph.D. in Structural 
biology, Biophysics or related disciplines to work in the lab of David Drew at 
Stockholm University in Sweden. Our international team aims to dissect the 
molecular mechanisms of small molecule transport across membranes (see 
publication: 
http://www.annualreviews.org/doi/abs/10.1146/annurev-biochem-060815-014520). We 
look to employ NMR, cryo EM, X-ray crystallography and other biochemical and 
biophysical approaches to establish how medically-relevant ion and sugar 
transport proteins, central to cell homeostasis, function at the atomic level. 

The Department of Biochemistry and Biophysics has a strong background in 
membrane biology and we have an excellent cryo EM facility with both Titan 
Krios and screening microscopes. You should have a Ph.D. in Structural Biology 
or a related discipline with a strong publication record and a desire to work 
on challenging and multidisciplinary projects. Experience in protein 
expression, purification and cryo EM and/or X-ray crystallography is essential 
for the position. Positions are initially available for 2-years with a 
possibility of extension. 

To apply, please send an email to dd...@dbb.su.se with a single pdf that 
includes your CV and publication record (max 2-pages).

Kind regards,

David Drew

Wallenberg Academy Fellow
Department of Biochemistry and Biophysics
Stockholm University
Sweden

Ph: +46-8-162295
http://www.su.se/profiles/drew-1.181696 

[ccp4bb] Postdoc positions in cryo-ET and single particle cryo-EM

[Stefan Raunser]

Dear colleagues,
I would like to draw your attention to the following job opportunities.
Best
Stefan

PostDoc Positions in Electron Microscopy at Max Planck Institute of Molecular 
Physiology
The positions are available immediately in the Department of Structural 
Biochemistry (Director: Stefan Raunser) and are initially limited to 3 years.
Job description: Our research focuses on structural and functional studies of 
macromolecular protein complexes by single particle electron cryo-microscopy 
(cryo-EM), electron cryo-tomography (cryo-ET), X-ray crystallography, 
biochemical and biophysical methods.
As part of a project that is funded by a Wellcome Trust Collaborative Award 
grant, one successful candidate will determine the structural organization of 
cellular components using cryo-ET. The other candidate will be involved in the 
structural elucidation of cytoskeletal proteins using single particle cryo-EM.
Equipment at the institute: 2 FEI Krios equipped with Volta phase plate, energy 
filter, K2, and Falcon3; JEOL3200FSC with in-column energy filter; FEI Scios2 
Dual Beam; 2 120 kV screening EMs, FEI CorrSight and all necessary equipment 
for cryo-EM
Requirements: The successful candidate holds an excellent PhD in biochemistry, 
structural biology, biophysics or physics and has sufficient specialist 
knowledge in electron microscopy, in particular electron cryotomography 
(cryo-ET) and correlated light and electron microscopy (CLEM) or single 
particle cryo-EM. Strong written and oral communication skills in English and 
strong computational skills are required.
Payment: Payment of Postdocs depends on personal conditions and qualification 
according to the directive of TVöD. Social benefits correspond to those of the 
public service.
Application: The Max Planck Society (MPG) is committed to employing more 
handicapped individuals and especially encourages them to apply.
The MPG aims to increase the percentage of women on its scientific staff and 
therefore strongly encourages women to apply.
Please send your CV, two references and a statement outlining your interests 
and relevant work experience to Stefan Raunser at 
raunser-jobsea...@mpi-dortmund.mpg.de.
 Deadline is September 30 2017.
-
Stefan Raunser, Ph.D.

Director, Department of Structural Biochemistry
Max Planck Institute of Molecular Physiology
Otto-Hahn-Str. 11
44227 Dortmund, Germany
tel: +49-231-133-2300

and

Adjunct Professor, Faculty of Chemistry and Chemical Biology
Technical University Dortmund

Honorary Professor, Centre for Medical Biotechnology, Faculty of Biology
University Duisburg-Essen

___
3dem mailing list
3...@ncmir.ucsd.edu
https://mail.ncmir.ucsd.edu/mailman/listinfo/3dem

[ccp4bb] Postdoc positions available with V. Ramakrishnan

[Brown, Alan]

Posted on behalf of Venki Ramakrishnan:
The Ramakrishnan lab (http://www2.mrc-lmb.cam.ac.uk/groups/ribo/) at the 
Laboratory of Molecular Biology (LMB) is looking for up to two Postdoctoral 
Scientists to work within a programme aimed at the understanding at molecular 
level the process of protein synthesis. Full details are given here: 
goo.gl/AXzayL.
Applicants should have a PhD in structural biology (or due to complete a PhD 
within 6 months) and a strong academic record with publications in major 
journals. Experience in structural analysis of macromolecular complexes by 
crystallography or electron microscopy is required.
Please apply online: goo.gl/AXzayL.
Applications due: 28-AUG-2017

[ccp4bb] Postdoc positions at Uppsala University

[Maria Selmer]

Dear all,
We have openings for two postdoctoral researchers for a project on protein 
synthesis and antibiotic resistance at Uppsala University, Sweden. 
The postdocs could also partly be involved in our ongoing studies of protein 
evolution.

On-line advert with more information and instructions for on-line application 
can be found here: 
http://www.uu.se/en/about-uu/join-us/details/?positionId=137102 
http://www.uu.se/en/about-uu/join-us/details/?positionId=137081

For more information, contact maria.sel...@icm.uu.se

Application deadline: March 19.
/Maria


Prof. Maria Selmer  
Deputy Head of Department
Cell and Molecular Biology, Uppsala University
BMC, Box 596
SE-75124 Uppsala
Sweden

Telephone: +46-(0)18-4714177
Fax: +46-(0)18-536971

[ccp4bb] Postdoc positions available at Philadelphia

[Jinhua Wu]

Postdoctoral positions are available immediately in the Molecular Therapeutic 
Program at Fox Chase Cancer Center (Philadelphia, PA) for highly motivated 
individuals in the field of structural biology of cell signaling.
 
The main focus of the lab is to understand the molecular basis for the cell 
signaling events that contribute to tumor metastasis by affecting cell 
adhesion. More details can be found at 

https://www.foxchase.org/people/jinhua-wu.
 
Candidates with experiences in protein crystallography, molecular biology, 
mammalian cell culture, and protein biochemistry are preferred. Prior 
experiences in flow cytometry, receptor biochemistry, cancer biology, and 
electron microscopy are desired but not required. The candidate should hold 
a 
Ph.D degree in a related field with 5-8 years of work experience. Fox 
Chase 
Cancer Center is a long-standing NCI-designated Comprehensive Cancer Center 
with 
multidisciplinary research interests from basic biological sciences to 
drug development and clinical studies. The institute is one of the top-ranked 

work places for postdoctoral researchers. It offers an outstanding research 
environment and strong support for postdoctoral career development.

 
Please send a cover letter describing previous research experiences, an updated 
CV, and a list of three references to: Jinhua.wu(a)(a)fccc.edu.  

[ccp4bb] Postdoc positions available

[Whitney Yin]

We are seeking highly motivated postdoc researchers to join us in
structural and functional studies of mitochondrial DNA replication.  The
studies aim to understand and eventually overcome antiviral drug
mitochondrial toxicity, and to provide structural basis for mitochondrial
diseases.   Experiences in protein crystallography, cryoEM and
protein-nucleic acid interactions are highly desirable.  The Sealy
Structural Biology Center at University of Texas Medical Branch is well
equipped with crystallography, cryoEM and solution biophysics facilities.   We
are located on the beautiful Galveston Island 30 miles south to Houston.
Interested individuals should send CV that including a list of references
to ywhitney@gmail.com.

[ccp4bb] Postdoc positions at Imperial College London

[Zhang, Xiaodong]

Salary range: £33,410 - £36,130 per annum
Full-time, fixed term for two years
South Kensington Campus

We wish to recruit two Research Associates to work in the research group of 
Professor Xiaodong Zhang (www.msf.bio.ic.ac.uk), 
in the Section of Structural Biology, Department of Medicine, at Imperial 
College London’s South Kensington Campus. The successful candidate will join a 
multi-disciplinary team of international researchers investigating the 
structures and mechanisms of large key complexes in DNA damage response and 
repair. We employ a combination of Biochemistry, X-ray crystallography and 
cryo-electron microscopy techniques, utilising our excellent protein production 
and structural biology facilities at Imperial.
You must hold a PhD, or equivalent, in biochemistry, structural biology or 
relevant discipline and have a demonstrated track record in conducting high 
quality original research. Knowledge to at least advanced undergraduate level 
in protein biochemistry and structural biology is essential and experience in 
protein expression and purification, especially in baculovirus, is desirable.

For informal enquiries please contact Professor Xiaodong Zhang 
xiaodong.zh...@imperial.ac.uk.

Our preferred method of application is online via 
https://www.imperial.ac.uk/job-applicants/ using reference HM2015132

Please download the application form and save to your computer. Once completed, 
please upload your application form prior to submitting your application.

Please note that CVs should be submitted and must be accompanied by an 
application form.


Professor Xiaodong Zhang
Section of Structural Biology
Department of Medicine
Imperial College London

504, Sir Ernst Chain Building, South Kensington, London, SW7 2AZ
Tel: (0) 207 594 3151
Email: xiaodong.zh...@imperial.ac.uk
http://www.imperial.ac.uk/people/xiaodong.zhang

PA: Kasia Pearce (k.pea...@imperial.ac.uk), (0)207 594 2763

[ccp4bb] Postdoc positions in chromatin structural biology

[Song Tan]

Postdoctoral Positions in Chromatin Structural Biology

Postdoctoral positions are available in the Tan Laboratory at Penn State to 
determine the structures of epigenetic chromatin enzymes and factors on their 
own or in complex with nucleosomes. These chromatin enzymes include single 
polypeptides and multisubunit protein complexes. Preliminary crystals are 
available for several projects, while crystallization conditions need to be 
determined or optimized for others.

Our efforts are enhanced by techniques to reconstitute multicomponent complexes 
in vitro and in vivo (Prot. Expr. Purif., 40:385, 2005; MCB, 25:5535, 2005; 
Methods, 41:271, 2007) and crystallization design strategies developed during 
successful structural determination of the RCC1-nucleosome complex (Nature, 
467:562, 2010; Anal. Biochem, 442:138, 2013) and the Polycomb PRC1-nucleosome 
complex (Nature, in press).

Our laboratory is located in The Center for Gene Regulation at Penn State, a 
dynamic and highly collaborative environment which includes the groups of Drs. 
Lu Bai, David Gilmour, Shaun Mahony, Frank Pugh, Joe Reese, Yanming Wang and 
Song Tan, each with research programs targeted at understanding the molecular 
basis for gene regulation on chromatin templates.  Additional Information about 
our laboratory can be found at http://www.personal.psu.edu/sxt30 .

Crystallographers, molecular biologists and biochemists are encouraged to 
apply. Prior experience with macromolecular crystallography and/or protein 
expression/purification is preferred. Please send curriculum vitae and the 
names and contact information of three references to Song Tan .

---

Dr. Song Tan
Professor of Biochemistry & Molecular Biology
Center for Eukaryotic Gene Regulation
Dept of Biochemistry & Molecular Biology
108 Althouse Laboratory   (office in 468A North Frear Lab)
Penn State University
University Park, PA   16802
email:  sx...@psu.edu
phone:  814-865-3355 fax: 814-863-7024
web:  http://www.personal.psu.edu/sxt30

[ccp4bb] Postdoc positions

[jie liu]

Dear all

NIH-funded post-doctoral associate positions in the Public Health Research 
Institute at Rutgers New Jersey Medical School are available to study the 
mechanisms of HIV-1 membrane fusion and assembly as well as their inhibition. 
The associate will report to Dr. Min Lu and work in his structural biology 
research group. Applicants with a PhD and published expertise in protein 
biochemistry and crystallography will be given close consideration. Please send 
a cover letter discussing your interests in the laboratory as well as your CV 
and list of 3 individuals as references to jl1...@njms.rutgers.edu.

Jie Liu 

[ccp4bb] Postdoc positions (SGC): fragments into crystals

[Frank von Delft]

Hello, first BB spam of 2014:

There are still 2 open postdoc positions in my group at the SGC, to work 
on technologies around fragment screening in crystals.


Details of the project are on my website 
; we 
need smart people to:


 * test-drive with start-to-end soaking campaigns
   

 * develop crystal engineering to get soakable systems (molecular
   biology, biochemistry)
   


The application deadline is _*10th January*_.  Not restricted to EU 
citizens.


phx.

[ccp4bb] Postdoc positions (SGC, Diamond): fragments into crystals

[Frank von Delft]

Hello,

I have 3 open postdoc positions, to work on technologies around fragment 
screening in crystals, which is what my (joint) research team at Diamond 
(beamline I04-1) and SGC (PX group) is trying to make simple and accessible.


Details of the project are on my website 
;  we 
need smart people to:


 * (at SGC) test-drive with start-to-end soaking campaigns
   

 * (at SGC) develop crystal engineering to get soakable systems
   (molecular biology, biochemistry)
   

 * (at Diamond) explore soaking techniques
   

The application deadlines for the SGC posts are a function of the UK's 
charming political climate;  if you're interested but from outside the 
EU, alert me with a direct email plus CV.


phx.

P.S. if you know smart undergrads who'd be interested in a DPhil in that 
sort of thing --  applied engineering, technology -- send them to that 
website too.  (DPhils are what you get in Oxford - that makes it 
special.  Or "special".)

[ccp4bb] Postdoc positions in X-ray crystallography or electron microscopy at Imperial College London

[P Freemont]

Research Associates: London, United Kingdom
Imperial College London

Salary: £32,100 - £40,720 per annum

Two Research Associate posts are available in the the research group of 
Professor Paul Freemont (www.msf.bio.ac.uk) in the in the Centre for Structural 
Biology, at the South Kensington Campus of Imperial College London. Funded by 
Cancer Research UK and Medical Research Council  you will join a group of 
multi-disciplinary colleagues and collaborators on two unrelated projects. 
Project one (NS 2012 168 IL) in collaboration with  Professor Xiaodong Zhang is 
aimed at understanding the  molecular mechanism and functions of the mammalian 
AAA ATPase p97 whilst Project two (NS 2012 176 IL) in collaboration with 
Professor Alain Filloux, will investigate the structure and function of the 
Type VI secretion system in Pseudomonas aeruginosa.

You must hold a PhD in a structural biology or biochemistry discipline or a 
related discipline, or an equivalent level of professional qualifications and 
experience. Research experience in a structural biological laboratory 
environment (covering  X-ray crystallography, and/or electron microscopy single 
particle analysis), and knowledge of protein biochemistry are essential. 

For informal enquires please contact Professor Paul Freemont 
(p.freem...@imperial.ac.uk).

Our preferred method of application is online via our website 
http://www3.imperial.ac.uk/employment (please select “Job Search” then enter 
the job title or vacancy reference – number ( in bold above) including spaces 
into “Keywords”).  Please complete and upload an application form as directed.


Closing date for NS 2012 168 IL : 7 September 2012 (Midnight BST)

Closing date for NS 2012 176 IL : 17 September 2012 (Midnight BST)

***
Professor Paul Freemont
Head of Division of Molecular Biosciences
Faculty of Natural Sciences
Imperial College London
South Kensington Campus
London SW7 2AZ, UK
www.imperial.ac.uk/molecularbiosciences
Group: www.msf.bio.ic.ac.uk
Co-director of EPSRC Centre for Synthetic Biology and Innovation at Imperial
www.imperial.ac.uk/syntheticbiology
***

[ccp4bb] Postdoc positions in X-ray crystallography or electron microscopy at Imperial College London

[Zhang, Xiaodong]

Research Associate: London, United Kingdom
Imperial College London

Salary: £32,100 - £40,720 per annum
We are seeking two Research Associates to work in the research group of 
Professor Xiaodong Zhang (www.msf.bio.ac.uk) in the 
Centre for Structural Biology, at the South Kensington Campus of Imperial 
College London. Funded by a Wellcome Trust Senior Investigator Award to 
Xiaodong Zhang, you will join a group of multi-disciplinary colleagues and 
collaborators to investigate the structures and mechanisms of DNA damage 
response.
These fixed-term posts are available for up to five years.
You must hold a PhD in a structural biology or biochemistry discipline or a 
related discipline, or an equivalent level of professional qualifications and 
experience. Research experience in a structural biological laboratory 
environment (covering either X-ray crystallography, or electron microscopy 
single particle analysis), and knowledge of protein biochemistry are essential.
For informal enquiries please contact Professor Xiaodong Zhang 
xiaodong.zh...@imperial.ac.uk.
Our preferred method of application is online via our website 
http://www3.imperial.ac.uk/employment (please select “Job Search” then enter 
the job title or vacancy reference – NS 2012 163 IL - number including spaces 
into “Keywords”).  Please complete and upload an application form as directed.
Closing Date: 4 September 2012 (Midnight BST)



Professor Xiaodong Zhang
Imperial College London
Division of Molecular Biosciences
504, Wolfson laboratories
South Kensington, London, SW7 2AZ
(0) 207 594 3151
xiaodong.zh...@imperial.ac.uk
http://www.imperial.ac.uk/people/xiaodong.zhang

[ccp4bb] Postdoc positions at Imperial College London

[Zhang, Xiaodong]

We wish to recruit two Research Associates to work in the research teams of 
Professor Xiaodong Zhang and Professor Paul Freemont 
(www.msf.bio.ac.uk), in the Division of Molecular 
Biosciences, Centre for Structural Biology, at the South Kensington Campus of 
Imperial College London. Our research groups comprise research fellows, 
research associates and PhD students from a diverse range of background from 
molecular biology, biochemistry, X-ray crystallography, electron microscopy, to 
chemistry, physics and engineering. We employ a multi-disciplinary approach to 
study the structures and mechanisms of large macromolecular complexes.

Post 1: Structural and mechanistic studies of p97 and cofactors – NS2011 242 KT
The multifunctional AAA ATPase p97 is involved in a myriad of cellular 
processes including cell cycle regulation, membrane traffic, protein quality 
control, DNA metabolism, signalling and apoptosis. Consequently mutations in 
p97 cause cell deaths or various disease.  Furthermore, p97 has been shown to 
be a potential target for cancer treatment. We are currently conducting an 
exciting and comprehensive study on the structure and mechanism of the p97 and 
cofactor proteins using a combination of protein biochemistry, X-ray 
crystallography and electron microscopy techniques. The successful candidates 
will be responsible for carrying out structural and functional studies of the 
p97 and its cofactors, using X-ray crystallography, NMR and electron microscopy.

Post 2: Structural studies of Chromatin Remodelling Complexes – NS2011 187 KT
Eukaryotic genomic DNA is organized into nucleosomes and chromatin for genome 
stability and integrity. However, this creates barriers for processes that 
require access to the DNA, such as transcription and DNA repair.  Chromatin 
remodeling complexes remodel nucleosomes and chromatin to provide access.  The 
INO80 complex is a multi-subunit, large macromolecular machine that remodels 
nucleosomes upon DNA damage in order for the repair machinery to access the 
damaged DNA. We are currently conducting an exciting and comprehensive study on 
the structure and mechanism of the INO80 complex using a combination of protein 
biochemistry, X-ray crystallography and electron microscopy techniques. The 
successful candidate will be responsible for carrying out structural studies of 
the INO80 complex, primarily using electron microscopy techniques. The 
successful candidate will work closely with Prof. Wigley’s laboratory at the 
Institute of Cancer Research, Chester Beatty Laboratories where the majority of 
the protein biochemistry will be carried out.
Successful candidates must hold a PhD in a structural biology or biochemistry 
discipline and have demonstrated an ability to carry out high quality original 
research using electron microscopy or X-ray crystallography techniques.

Closing date – Feb 29th, 2012

Our preferred method of application is online via our website 
http://www3.imperial.ac.uk/employment (please select “Job Search” then enter 
the job title or vacancy reference number including spaces into “Keywords”).  
Please complete and upload an application form as directed, attaching a 
curriculum vitae, a cover letter and the name and contact details of two 
referees.  For informal enquiries please contact Professor Xiaodong Zhang 
xiaodong.zh...@imperial.ac.uk


Alternatively, if you are unable to apply online, please contact Kasia Pearce 
k.pea...@imperial.ac.uk by email to request an 
application form.



Committed to equality and valuing diversity.  We are also an Athena Silver SWAN 
Award winner, a Stonewall Diversity Champion and a Stonewall Top 100 Employer 
2011.

Prof Xiaodong Zhang
Division of Molecular Bioscience
Imperial College London
London, SW7 2AZ
Tel: +44 (0) 207 594 3151
www.imperial.ac.uk/people/xiaodong.zhang

[ccp4bb] Postdoc Positions at EMBL Grenoble

[Matthias Haffke]

The Schaffitzel laboratory at the European Molecular Biology Laboratory (EMBL) 
Grenoble, France seeks to recruit outstanding postdoctoral scientists in 
structural biology. We study the structure and function of large macromolecular 
complexes in gene expression. The project involves structure determination by 
single-particle cryo-electron microscopy of large multicomponent complexes 
produced in insect cells (MultiBac technology, collaboration with Imre Berger), 
their purification and biophysical and biochemical characterization. 
http://www.embl.fr/research/unit/schaffitzel/index.html

The positions require a Ph.D. in biochemistry, structural biology or a related 
field. Outstanding applicants have experience in guiding structure 
determination projects from start to finish, experience in electron microscopy 
would be advantageous. Candidates are highly motivated individuals who enjoy 
working as part of a young, dynamic, collaborative and multidisciplinary team.  

The laboratory is well-situated in a structural biology environment at the 
Polygone Scientifique in Grenoble. We are equipped with a state-of-the-art 
electron microscope (Polara, FEI). Access to modern biophysical instrumentation 
(analytical ultracentrifugation, surface plasmon resonance, dynamic light 
scattering, isothermal calorimetry, CD and fluorescence spectrometers) is 
provided.

The positions are available from January 2012 and funded for 3 years. Contracts 
may be extended depending on performance.

Please send your CV, a statement of research interests, and names (including 
email address) of at least two referees by email to Dr. Christiane Schaffitzel 
(schaffit...@embl.fr). Applications will be accepted until the positions are 
filled. 
  

[ccp4bb] Postdoc positions, Florida, USA

[Fraydoon Rastinejad]

Postdoc Positions Available: Protein Biophysics, Protein Crystallography and 
NMR Spectroscopy

We are recruiting Postdoctoral Fellows in the area of epigenetics (chromatin 
modifications and transcription regulation) to investigate projects related to 
diabetes, obesity or cardiovascular health. The position is within Prof. 
Sepideh Khorasanizadeh’s laboratory at the Sanford-Burnham Medical Research 
Institute, located at the Medical City of Lake Nona in Orlando, Florida. 
Applicants are expected to have experience in sub-cloning, protein expression 
and isolation, and analytical and biophysical characterization of proteins. 
Applicants must have at least one first author publication and additional 
publications in peer-reviewed journals. Please also list name of 3 persons 
knowledgeable with your prior experience in science. Send your C.V. and cover 
letter to Ms. Stephanie Dickstein e-mail address:
sdickst...@sanfordburnham.org

[ccp4bb] Postdoc Positions in Structural Biology at Astex Therapeutics

[Marc O'Reilly]

Career Opportunities at Astex - September 2009 

Astex Therapeutics Ltd, based in Cambridge, UK, was founded 10 years ago
and is a world-leading biotechnology company that has pioneered
fragment-based drug discovery (FBDD) platform to discover and develop
medicines in areas of unmet medical need. Astex has successfully
progressed its first three oncology drug candidates into clinical trials
and has recently extended its technology to anti-viral targets.
Astex has established an internationally leading scientific reputation
in FBDD, the most important new area of drug discovery chemistry in the
last 20 years. We remain committed to the highest possible scientific
standards and have established a strong track record in high calibre
scientific publications, presentations and peer citations.
As a result of this continued success in our drug discovery programmes,
we are now seeking highly talented scientists with a passion for
innovative drug discovery.
The closing date for applications is 25th September 2009.

Postdoctoral Structural Biologists (SB-09) 

These roles are 2 year Post-Doc positions for lab-based scientists to
join our structural biology department, which represent a tremendous
learning experience at the start of a career in drug discovery,
including interaction with scientists in other disciplines in the
company's well equipped structural biology laboratories.
Candidates will have broad skills in molecular biology, protein science
and protein structure determination. Familiarity with insect cell
expression systems and with protein purification - characterisation is
desirable. Ideally you will have recently completed a PhD or have
several years of relevant postgraduate experience.

Salaries and benefits package are highly competitive to ensure we
attract, motivate and retain the best candidates.  Please send your
application to: 
Human Resources
Astex Therapeutics Ltd
436 Cambridge Science Park
Milton Road
Cambridge
CB4 0QA
UK
Or apply by e-mail to: h...@astex-therapeutics.com



Disclaimer
This communication is confidential and may contain privileged information 
intended solely for the named addressee(s). It may not be used or disclosed 
except for the purpose for which it has been sent. If you are not the intended 
recipient you must not review, use, disclose, copy, distribute or take any 
action in reliance upon it. If you have received this communication in error, 
please notify Astex Therapeutics Ltd by emailing 
m.orei...@astex-therapeutics.com and destroy all copies of the message and any 
attached documents. 
Astex Therapeutics Ltd monitors, controls and protects all its messaging 
traffic in compliance with its corporate email policy. The Company accepts no 
liability or responsibility for any onward transmission or use of emails and 
attachments having left the Astex Therapeutics domain.  Unless expressly 
stated, opinions in this message are those of the individual sender and not of 
Astex Therapeutics Ltd. The recipient should check this email and any 
attachments for the presence of computer viruses. Astex Therapeutics Ltd 
accepts no liability for damage caused by any virus transmitted by this email. 
E-mail is susceptible to data corruption, interception, unauthorized amendment, 
and tampering, Astex Therapeutics Ltd only send and receive e-mails on the 
basis that the Company is not liable for any such alteration or any 
consequences thereof.
Astex Therapeutics Ltd., Registered in England at 436 Cambridge Science Park, 
Cambridge CB4 0QA under number 3751674

[ccp4bb] Postdoc positions available NIH Jan 2010

[Dr. Mark Mayer]

Postdoctoral positions are available to study the structure and 
function of neurotransmitter receptors in a group at the NIH main 
campus, Bethesda, MD 20892


We are looking for highly motivated young scientists who would like 
to join a group which combines crystallographic studies with 
biochemical and electrophysiological experiments to understand the 
function of glutamate receptor ion channels, the major mediators of 
excitatory synaptic transmission in the brain. A major component of 
the work involves protein expression and crystallization trials. 
Preference will be given to candidates with strong skills in cell 
biology, or protein purification and large scale expression using 
mammalian and insect cell culture. Experience in macromolecular 
crystallography highly desirable but not essential. Must have 
excellent communication skills in English and a superb ability to 
work as part of a team.


Recent papers describing work from the lab include:

Proc Natl Acad Sci U S A. 2009 PMID: 19617541
Nat Struct Mol Biol. 2009 PMID: 19465914
EMBO J. 2009 PMID: 19339989
Biophys J. 2009 PMID: 19254535
Neuron. 2008 PMID: 18549784
EMBO J. 2008 PMID: 18636091
Neuron. 2007 PMID: 17359918

Candidates must have been awarded PhD degree no earlier that 5 years 
prior to start of fellowship.
NIH is an Affirmative action employer. J1 visa sponsorship for non US 
nationals (H1 visa NOT available for this position). Please submit: 
CV, names for 3 references, 1 page summary of research experience  to


Mark Mayer Ph.D.
LCMN NICHD NIH DHHS
Bldg 35, Room 3B 1002 MSC 3712
35 Lincoln Drive
Bethesda MD 20892 3712

Lab web site: http://snb.nichd.nih.gov/index.htm


--

[ccp4bb] postdoc positions in TIME-RESOLVED macromolecular crystallography

[Marius Schmidt]

Dear Colleagues,
two post-doc positions are immediately available at the
University of Wisconsin-Milwaukee in the departments of
physics and chemistry/biochemistry. Please forward this
text to interested candidates.

With best regards
Marius Schmidt


Position 1

A postdoctoral position is immediately open at the University of 
Wisconsin-Milwaukee (UWM)/USA in the field of time-resolved macromolecular 
crystallography, initially for a period of one year, with the option to extend 
for a second year.  The candidate will work with Marius Schmidt, department of 
physics, and Andy Pacheco, department of chemistry and biochemistry.

The main duties will include crystallization of non-heme and heme iron 
proteins, collection of monochromatic and polychromatic X-ray data (in house 
and at the nearby Advanced Photon Source of Argonne National Laboratory), and 
helping to train graduate students in protein crystallographic techniques.  
Experience with protein handling is required; skills in computer programming 
are definitely a plus.  Training in time-resolved crystallographic techniques 
will be provided.

This is a great opportunity to work in an interdisciplinary environment, at the 
interface of biology, chemistry and physics. Candidates with a background in 
the relevant areas are invited to send an application to either Andy Pacheco 
(apach...@uwm.edu) or Marius Schmidt (m-schm...@uwm.edu) from whom further 
information can also be obtained. Please include in the application a CV, a 
summary of research experience and interests, and contact details for three 
referees.

Position 2

A postdoctoral position is immediately open at the University of 
Wisconsin-Milwaukee (UWM)/USA for a synthetic organic or inorganic chemist with 
experience in photochemistry, initially for a period of one year, with the 
option to extend for a second year.  The candidate will work with Marius 
Schmidt, department of physics, and Andy Pacheco, department of chemistry and 
biochemistry. 

The focus of the project will be to synthesize and characterize novel 
photoactive compounds for use in time-resolved macromolecular crystallography.  
Experience with laser photochemistry is desirable but not required.  This is a 
great opportunity to work in an interdisciplinary environment, at the interface 
of biology, chemistry and physics.  Candidates with a background in the 
relevant areas are invited to send an application to either Andy Pacheco 
(apach...@uwm.edu) or Marius Schmidt (m-schm...@uwm.edu) from whom further 
information can also be obtained. Please include in the application a CV, a 
summary of research experience and interests, and contact details for three 
referees.




Dr.habil. Marius Schmidt
Asst. Professor
University of Wisconsin-Milwaukee
Department of Physics Room 454
1900 E. Kenwood Blvd.
Milwaukee, WI 53211, U.S.A.

phone: +1-414-229-4338
email: m-schm...@uwm.edu
http://users.physik.tu-muenchen.de/marius/

[ccp4bb] postdoc positions availabel

[Guan, Lan]

Postdoctoral positions available immediately in a membrane transport and 
structural biology laboratory.  Our new laboratory in the Department of Cell 
Physiology and Molecular Biophysics at Texas Tech University Health Science 
Center at Lubbock is well equipped with the state-of –the-art equipment for 
robotic high throughput membrane protein crystallization. Our current focus is 
on crystallization and structural determination of bacterial and human sugar 
transporters.  Highly motivated candidates with a strong background either in 
protein X-ray crystallography, or in biochemistry and biophysics are encouraged 
to apply.  More information is available at 
http://www.ttuhsc.edu/SOM/physiology/faculty/Guan/guan.aspx.  Salary is 
competitive based on experience. Please submit a CV and contact information for 
three references to Dr. Lan Guan through TTUHSC’s website 
(http://jobs.texastech.edu), requisition #77090 or #77091.

Lan Guan
Assistant Professor
Department of Cell Physiology & Molecular Biophysics
Texas Tech University Health Sciences Center
3601 4th Street, STOP 6551
Lubbock, Texas 79430

Email: [EMAIL PROTECTED]
http://www.ttuhsc.edu/SOM/physiology/faculty/Guan/guan.aspx. 

[ccp4bb] Postdoc positions at Purdue University

[Chen, Jue]

Postdoctoral positions in Structural Biology are available immediately
in the Chen laboratory at Purdue University.  As part of the Markey
Center for Structural Biology, the Chen lab integrates X-ray
crystallography and biochemical methods to study the mechanism of active
transport (See Nature, 450: 515-521; PNAS,102:17969-17974; and Mol.Cell,
12:651-661). In addition, we also study how pathogenic bacteria and
viruses interact with their host cells. The lab is well-funded with
access to the latest equipments for protein crystallization,
cryoelectron microscopy, and other biophysical measurements.  For more
information please visit our website at http://chen.bio.purdue.edu.  

Successful candidates should have (or expect) a recent doctoral degree
with demonstrated experience in macromolecular crystallography and
protein biochemistry. Experience with membrane proteins will definitely
be a plus.  Applicants should send a CV and names of three referees to
[EMAIL PROTECTED], or:

Jue Chen
Associate Professor
Department of Biological Sciences
Purdue University
West Lafayette, IN 47907
USA

[ccp4bb] Postdoc positions at Purdue University

[Michael Oldham]

Postdoctoral positions in Structural Biology are available immediately
in the Chen laboratory at Purdue University.  As part of the Markey
Center for Structural Biology, the Chen lab integrates X-ray
crystallography and biochemical methods to study the mechanism of active
transport (See Nature, 450: 515-521; PNAS,102:17969-17974; and Mol.
Cell, 12:651-661). For more information please visit our website at
http://chen.bio.purdue.edu.  

Successful candidates should have (or expect) a recent doctoral degree
with demonstrated experience in macromolecular crystallography and
protein biochemistry. Applicants should send a CV and names of three
referees to [EMAIL PROTECTED], or:

Jue Chen
915 W. State Street
Purdue University
West Lafayette, IN 47907

[ccp4bb] Postdoc positions in Yokohama

[Jeremy Tame]

Post-doctoral positions are available in the Protein Design group
at Yokohama City University.  Projects include beta helical bacterial
virulence factors and protein-based nanocomponents for semiconductor
manufacture (in collaboration with Panasonic). See J. Biol. Chem. 280,
17339-17345 (2005) and Structure 14, 925-933 (2006) for more details.

The group is well equipped with three R-Axis detectors, AUC, ample
wet lab facilities including crystallisation robotics and ready access 
to ITC,

CD, SAXS and NMR, and is conveniently located between SPring8 and the
Photon Factory.

Please visit our web site for more information:
www.tsurumi.yokohama-cu.ac.jp/pdl/index.html

Yokohama is a lively city with great food and excellent travel 
connections

to the rest of Japan and Asia.

Interested candidates with a molecular biological or crystallographic
background are welcome to send a CV to:

Jeremy Tame
Protein Design Laboratory, Yokohama City University
Suehiro 1-7-29, Tsurumi-ku, Yokohama 230-0045, Japan

Tel +81 (0)45 508 7228Fax +81 (0)45 508 7366