Hi Catherine;

Antioxidants can't change the progress of a genetic anomaly, true, but 
they can sure change anything to do with oxidative stress that is 
increased due to that anomaly. The oxidative stress forms a large 
component of the progress and permanent damage of most lung disorders 
including this one.

Did you take the time to peruse some of the Medline data along those 
lines? Here's an excerpt from another one...

""Evidence is accumulating that secondary genetic factors separate from 
the CFTR locus significantly influence the severity of CF lung disease. 
The general classes of these potential modifier genes include 
inflammatory and antiinflammatory mediators, antioxidants, mediators of 
airway reactivity, molecules involved in CFTR trafficking, and 
alternative ion channels. The best-studied CF candidate modifiers include 
mannose-binding lectin, glutathione-S-transferase, transforming growth 
factor-beta1, tumor necrosis factor-alpha, beta2-adrenegic receptor, and 
HLA class II antigens. ""

I think that without overlooking the other factors listed, it would be 
wise to at least apply the antioxidant program for the oxidative stress 
alone, although suppressing infection with antioxidants is also of great 
benefit.

Duncan

>   Certainly, your recommendation of better nutrition and a good
>   antioxidant
> from program would help in reducing the infections two which people are
> prone when they have CF.  It's a great suggestion. But all the Immunocal
> and antioxidants in the world will not change the genetic mutation that
> causes CF.
> 
> Regards,
> Catherine


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